Abstract:For long-term exploratory space travel, there will be a critical need for in-situ diagnosis and assessment of biological specimens from symptomatic astronauts, especially, disease pathogens (virus, bacterium, or fungus) and microbial contaminants. Hence, a real-time, non-culture-based microbial… more
Abstract:An accurate predictive capability of coupled fluid-structure interaction in propulsion system is crucial in the development of NASA's new Space Launch System (SLS). This STTR effort will develop a multi-disciplinary tool to improve CFD prediction capability in modeling coupled fluid structure… more
Abstract:ABSTRACT: The goal of this project is to develop theoretical models for electrode erosion in high-pressure arcs and incorporate them into computational tools for simulations of arc heaters. The complexity of the electrode material removal process is associated with the multi-phase nature of the… more
Abstract:ABSTRACT: The overall goal of the proposed effort is to develop and demonstrate a general-purpose, fast, and reliable management and learning software tool for analyzing massive data sets generated by dynamic multi-disciplinary simulations. The salient elements of the software tool are: (1) an… more
Abstract:Our objective is to develop a novel method for structurally orienting enzymes onto an electrode surface. The technology will significantly increase the electron transfer efficiency of the electrode and thereby enable a state-of-the-art energy source for low power military and commercial systems. … more
Abstract:Development of next generation energetic materials has been slow primarily due to a lack of fundamental understanding of the physics and chemistry of these materials. The strategy for development historically has been a trial-and-error experimental approach which possesses considerable risk of… more
Abstract:High speed projectile launch decisions always tend toward"clear sky"days because no capability has existed to assess high speed flight risk due to weather in either design or operations. Since clear sky conditions occur about 50% of the time, the risk of mission failure is unknown half of… more
Abstract:Higher efficiency solar cells are needed to reduce mass, volume, and cost of DoD space missions. However, to achieve higher efficiency and radiation hardness of the best to date multi-junction photovoltaic (MJ PV) devices, several challenges must be addressed. This project aims to develop: 1)… more
Abstract:The MDA is developing the Precision Tracking Space System and other satellite based systems that could benefit from ongoing developments in advanced materials for lithium ion batteries. Unfortunately, the applications driving much of that battery research have less abusive operational cycles than… more
Abstract:ABSTRACT: Our objective is to develop advanced mediator architectures for efficient electron transfer in enzymatic fuel cells (EFCs) for low power systems. The proposed EFC will leverage ongoing research at both CFDRC and Michigan State University to provide a fully-integrated lightweight, low-cost… more
Abstract:The overall goal of the proposed effort is to develop and demonstrate rigorous model order reduction (MOR) technologies to automatically generate fully coupled, nonlinear, parameterized aeroservoelastic reduced-order models (ROMs) for smart material-based active structural control. The Phase I… more
Abstract:Scramjet engines promise to become a next-generation revolutionary technology for aerospace applications. Some of the significant challenges in rapid development of scramjets include complex flow physics; combustion; flow-combustion interactions; propulsion air-frame integration; coupled with… more
Abstract:The goal of this SBIR project is to advance the state-of-the-art in computations of hypersonic plasmas by adding high-fidelity kinetic models for electrons. Electron kinetics affects plasma-chemical reactions and nonequilibrium radiation, which are important for designing hypersonic vehicles. We… more
Abstract:DESCRIPTION (provided by applicant): We propose to develop and demonstrate a novel microfluidic device and assay for selection and optimization of delivery vehicles, specifically non-viral vectors for drug delivery to tumors. Tumor drug delivery is a complex phenomenon affected by several elements… more
Abstract:DESCRIPTION (provided by applicant): The overall objective of this study is to develop a novel in vitro microfluidic platform to test a drug or delivery vehicle's ability to permeate the Blood-Brain Barrier (BBB). In contrast to current in-vitro models, our proposed device, SIM-BBB,… more
Abstract:Rapid and accurate characterization and/or identification of the differentiation state of the stem cells is critical to the development of regenerative medicine technologies as well as tissue engineering solutions. Current methods and devices are time-consuming, labor-intensive, costly, invasive,… more
Abstract:ABSTRACT: Operating in a Service-Oriented Architecture (SOA) environment is risky because there is limited ability to gauge information"s trust level. Existing solutions track information pedigree, but do not consider other prerequisites to trust. This project proposes to build METSI (Metadata… more
Abstract:ABSTRACT: Our objective is to develop an enzyme catalyzed fuel cell to enable electrochemical power generation from several fuel types (i.e. sugars and alcohols), thereby delivering a state-of-the-art energy source for low power military and commercial systems. The proposed enzymatic fuel cell… more
Abstract:ABSTRACT: Military and industrial personnel are often exposed to RF electromagnetic energy which can cause thermal and electrokinetic biological effects. To understand these effects, AFRL is using computational tools to predict RF energy deposition and thermal effects in humans. Unfortunately, high… more
Abstract:The overall objective of this work is to develop whole-body anthropometric models (containing both skin and interior anatomy) to cover individual body shape variations in the design of protective equipment as well as to identify critical fit and form issues and their associated impacts. Starting… more
Abstract:The present thermal battery technologies cannot currently meet future requirements that call for higher power and capacity with a smaller footprint. The principal avenue for increasing thermal battery specific energy is to identify and develop new electrode materials that provide higher specific… more
Abstract:Future supersonic cruise missiles (SSCMs), such as the Next Generation Tomahawk, will require larger, more powerful engines to operate. Scaling current inlet technology to match will reduce missile body volume available for fuel, and hence curtail range. Highly compact inlet systems that allow… more
Abstract:ABSTRACT: CFDRC proposes to develop a high-fidelity simulation capability and probabilistic description for the unguided dispensing of submunition projectiles from weapons systems. The proposed technology will be based on the Loci/CHEM software framework. In the Phase I effort, a rigid body… more
Abstract:ABSTRACT: Nanotechnology (NT) offers immense innovation potential across many disciplines in military and civilian applications. It will also bring potential hazards, by negligence, accident or adversary or terrorist action. In spite of exponential growth on NT R & D our understanding of… more
Abstract:We propose to develop new acoustic metamaterials (AMMs) using locally resonant regimented structures, suitable for application in Hearing Protector Devices (HPDs), that will act as frequency selective acoustic filter for hearing protection. Our computational simulations conducted in phase I project… more
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