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Note: The Award Database is continually updated throughout the year. As a result, data for a given year is generally not complete until April of the following year.

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Displaying 2376 – 2400 of 2722 Awards
Company: Secretech, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1993 / 1
Abstract: The long term objective is to develop a commercial trivalent glycoprotein subunit vaccine for parainfluenza viruses. Because of the high cost of preparing these glycoproteins, a means for achieving an enhanced immune response is an important objective, and it is the immediate focus. The… more
Company: Secretech, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1993 / 1
Abstract: The long term objective is to develop a commercial subunit vaccine for human respiratory syncytial virus (RSV). Because of the high cost of preparing these glycoproteins, a means for achieving an enhanced immune response is an important objective, and it is the focus. Biocompatible and biodegradable… more
Company: Secretech, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1993 / 1
Abstract: The long term objective is to induce a protective mucosal immune response to prevent HIV-1 infection. We will immunize orally with recombinant defective SIV-like particles entrapped in microcapsules of lactige-glyco- lide copolymer in order to stimulate a mucosal immune response in mice. The… more
Company: Secretech, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1993 / 1
Abstract: The long term objective is to develop a commercial vaccine for the prophylactic treatment of sexually transmitted Chlamydia trachomatis. Parenteral or oral delivery of free antigen does not protect against genital infection and, therefore, development of an antigen delivery method that induces a… more
Company: Secretech, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1993 / 1
Abstract: The long term objective is to develop a commercial subunit vaccine against MV infection. Because of the high cost of preparing the surface antigens, a means for achieving an enhanced immune response is an important objective and is the focus. Biocompatible and biodegradable microspheres consisting… more
Company: Tensor Technology Inc. Agency/Program/Year/Phase: DOT / SBIR / 1993 / 1
Abstract: THIS PROPOSAL IS TO DETERMINE THE SPATIAL RESOLUTION OF A NEW TYPE OF MULTI-DIMENSIONAL X-Y DETECTOR WHICH PROVIDES THE POSITION IN AN X-Y PLANE OF NEUTRAL PARTICLE INTERACTIONS FOR USE IN AIRPORT SECURITY SYSTEMS FOR INSPECTION OF SEALED LUGGAGE.
Company: Tomorrowtools Agency/Program/Year/Phase: NASA / SBIR / 1993 / 1
Abstract: N/A
Company: Applied Research, Inc. Agency/Program/Year/Phase: NASA / SBIR / 1993 / 1
Abstract: N/A
Company: Advanced Optical Systems, Inc Agency/Program/Year/Phase: DOD / SBIR / 1992 / 1
Abstract: N/A
Company: Advanced Welding Concepts, Agency/Program/Year/Phase: NASA / SBIR / 1992 / 2
Abstract: CONSTRUCTION AND ASSEMBLY OF LARGE STRUCTURES WILL REQUIRE USE OF VARIOUS METAL-JOINING PROCESSES. WELDING IS ONE OF SEVERAL METHODS UNDER CONSIDERATION FOR THIS PURPOSE. GAS METAL ARC (GMA) WELDING HAS ADVANTAGES OVER OTHER WELDING PROCESSES (I.E., LASER, ELECTION-BEAM, AND PLASMA ARC WELDING)… more
Company: Advanced Welding Concepts, Agency/Program/Year/Phase: NASA / SBIR / 1992 / 1
Abstract: N/A
Company: AEgis Technologies Group, Inc. Agency/Program/Year/Phase: DOD / SBIR / 1992 / 1
Abstract: THIS PROPOSAL ADDRESSES THE DEVELOPMENT OF A SET OF TECHNICAL SPECIFICATIONS FOR THE ESTABLISHMENT OF A LASER RADAR SEEKER HARDWARE-IN-THE-LOOP (HWIL) TESTING AND EVALUATION FACILITY. AEGIS RESEARCH WILL DETERMINE THE CAPABILITIES OF SEEKER UNITS ANTICIPATED TO BE TESTED BY SUCH A FACILITY,… more
Company: Alabama Cryogenic Engineering, Inc. Agency/Program/Year/Phase: DOD / SBIR / 1992 / 1
Abstract: A CONCEPT FOR PASSIVE REMOVAL OF WATER FROM COMPRESSED AIR SUPPLY LINES IS PROPOSED. RELYING ON SURFACE TENSION EFFECTS TO REMOVE THE WATER, THIS CONCEPT IS FEASIBLE FROM A PRACTICAL STANDPOINT BECAUSE OF AN INVENTIVE MANUFACTURING APPROACH DEVELOPED BY ALABAMA CRYOGENIC ENGINEERING. THE PHASE I… more
Company: Biocryst Ltd Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: N/A
Company: BIOCRYST PHARMACEUTICALS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: THE LONG-TERM OBJECTIVE IS TO DESIGN AND DEVELOP POTENT AND HIGHLY SPECIFIC INHIBITORS OF THE ENZYME ALDOSE REDUCTASE. ALDOSE REDUCTASE CATALYZES THE REDUCTION OF GLUCOSE TO SORBITOL. IT HAS BEEN IMPLICATED IN THE PATHOGENESIS OF THE CHRONIC COMPLICATI0NS OF DIABETES MELLITUS. CURRENT INHIBITORS OF… more
Company: BIOELASTICS RESEARCH, LTD. Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: THE LONG-TERM OBJECTIVE IS TO DEVELOP A SYNTHETIC PERICARDIUM FOR USE FOLLOWING OPEN HEART SURGICAL PROCEDURES, PARTICULARLY INVOLVING CARDIOPULMONARY BYPASS AND THE USE OF A TOTAL ARTIFICIAL HEART AS A BRIDGE TO TRANSPLANTATION. THE APPROACH UTILIZES A NEW CLASS OF BIOMATERIALS, ELASTOMERIC… more
Company: BIOELASTICS RESEARCH, LTD. Agency/Program/Year/Phase: DOD / SBIR / 1992 / 1
Abstract: N/A
Company: Brookwood Biomedical Agency/Program/Year/Phase: HHS / SBIR / 1992 / 1
Abstract: THE ABILITY TO EXPAND HEMATOPOIETIC STEM CELL POPULATIONS IN VITRO WOULD BE OF OBVIOUS ADVANTAGE IN BOTH AUTOLOGOUS AND ALLOGENEIC BONE MARROW TRANSPLANTATION. STEM CELL PROPAGATION REQUIRES INTERACTION WITH ADHERENT STROMAL SUPPORT CELLS AND CAN BE PERFORMED IN CONVENTIONAL TISSUE CULTURE AND ON… more
Company: Centrair Corp Agency/Program/Year/Phase: DOD / SBIR / 1992 / 1
Abstract: N/A
Company: CFD Research Corporation Agency/Program/Year/Phase: DOD / SBIR / 1992 / 2
Abstract: RECENT STUDIES OF TURBORAMJET PROPULSION SYSTEMS HAVE IDENTIFIED THE NEED OF ADVANCED, INSTREAM FUEL INJECTION/FLAMEHOLDER SCHEMES FOR RAMBURNERS. THIS PROJECT PROPOSES TO DEVELOP A NEW, CLOSE-COUPLED FUEL INJECTOR/FLAMEHOLDER CONCEPT WHOSE DISTINGUISHING CHARACTERISTIC IS A CORRUGATED FLAMEHOLDER… more
Company: CFD Research Corporation Agency/Program/Year/Phase: DOD / SBIR / 1992 / 2
Abstract: THE QUANTITIVE PREDICTION OF THE DYNAMICS OF SEPARATING UNSTEADY FLOWS, SUCH AS DYNAMIC STALL, IS OF CRUCIAL IMPORTANCE. THIS STUDY PROPOSES SEVERAL NEW METHODOLOGIES OF SOLVING 3-D NAVIER-STOKES EQUATIONS WITH PRESSURE-BASED ALGORITHM IN BOTH STATIONARY AND MOVING (BODY-FIXED) COORDINATES. THE… more
Company: CFD Research Corporation Agency/Program/Year/Phase: DOD / SBIR / 1992 / 2
Abstract: AN ADVANCED FUEL INJECTOR WITH IMPROVED ATOMIZATION AND MIXING CHARACTERISTICS IS NEEDED FOR CURRENT AND ADVANCED SMALL GAS TURBINE ENGINES. IN ADDITION, DUE TO HIGHER COMBUSTOR TEMPERATURE RISE AND HEAT SINK DEMANDS, THE ADVANCED INJECTOR MUST BE CAPABLE OF OPERATING AT HIGHER FUEL TEMPERATURES… more
Company: CFD Research Corporation Agency/Program/Year/Phase: DOD / SBIR / 1992 / 2
Abstract: THE RECENT ADVANCES IN MATHEMATICAL MODELING OF COMPLEX PHENOMENA IN CONTINUUM MECHANICS HAS LED TO LARGE SCALE CALCULATIONS INVOLVING EXTREMELY VOLUMINOUS DATA SETS (GIGABYTE REGIME). TO EFFECTIVELY ANALYZE THESE DATA SETS, DEVELOPMENT OF 3-D GRAPHICS SOFTWARE WHICH EMPLOYS STATE-OF-THE-ART VOLUME… more
Company: CFD Research Corporation Agency/Program/Year/Phase: NASA / SBIR / 1992 / 2
Abstract: MODELING METHODS DEVELOPED FOR NON-REACTING TURBULENT FLOWS ARE NOT ABLE TO CAPTURE IMPORTANT INTERACTIONS OF TURBULENCE AND COMBUSTION. AN ALTERNATIVE APPROACH SOLVES AN EQUATION FOR THE JOINT PROBABILITY DENSITY FUNCTION (PDF)OF THE LOCAL VELOCITY AND COMPOSITION, INSTEAD OF SOLVING A SET OF… more
Company: CFD Research Corporation Agency/Program/Year/Phase: NASA / SBIR / 1992 / 2
Abstract: THIS PROJECT WILL INTEGRATE COMBUSTOR AERODYNAMICS AND FUEL SPRAY PATTERNS TO ATTAIN HIGH TURNDOWN RATIOS WITHOUT SIGNIFICANTLY MODIFYING CONVENTIONAL COMBUSTOR GEOMETRY. THIS WILL BE ACCOMPLISHED BY: THE CREATION OF TWO DISTINCT ZONES WITHIN THE COMBUSTOR PRIMARY ZONE THAT ARE INDEPENDENTLY FUELED;… more
Displaying 2376 – 2400 of 2722 Awards
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