Abstract:An ideal transistor from a circuit designers standpoint consists of an ultra-low on-resistance, majority carrier switching, low gate current drive, and normally-off design. These features are inherent in the silicon carbide (SiC) power MOSFET, with the small footnote that the device, although having… more
Abstract:APEI, Inc. is proposing in this Phase I effort to design and build a scalable, high-efficiency, high-power density, gallium nitride (GaN)-based DC-DC converter for grid-tied energy storage applications. The project approach will utilize a soft switching dual active bridge DC-DC converter with… more
Abstract:In this Phase II proposal, APEI, Inc. will continue development of its patented high temperature gate driver technology, enabling the next generation of high-efficiency, high power density converters. At the conclusion of Phase II, APEI, Inc. will have designed, fabricated, and tested a high… more
Abstract:DESCRIPTION (provided by applicant): This Small Business Innovation Research Phase I project will investigate the technical feasibility of an in vitro excystation-based automated cartridge assay for rapid detection of viable Cryptosporidium oocysts in water. Briefly, viable oocysts will be subjected… more
Abstract:DESCRIPTION (provided by applicant): There are approximately 4 million Americans with severe speech and physical impairments (SSPIs) who must rely on augmentative and alternative communication (AAC) systems to express themselves. People with SSPI are at asignificant disadvantage when communicating.… more
Abstract:DESCRIPTION (provided by applicant): Physical activity may improve the health and quality of life of people with spinal cord injury and disease (SCI/D) by slowing or reversing physiological decline, lowering risk factors for cardiovascular disease and diabetes, improving mental health status and… more
Abstract:DESCRIPTION (provided by applicant): There are over 700,000 Americans with severe physical impairments (SPIs) who have few options for independently accessing telecommunication services such as voice calls, text messaging, and video calling. The inabilityto independently and reliably access these… more
Abstract:Liver Cancer is the sixth most common cancer and the third leading cause of cancer death worldwide. Early diagnosis of liver cancer will have a significant impact on survival by implementation of effective tratment strategies. The development of novel biomarkers in serum for liver cancer… more
Abstract:This Small Business Technology Transfer (STTR) Phase I project aims to develop an efficient, rapid, and eco-friendly approach for mass production of highly conductive solution phase graphene with controlled structures. Most of the commercial available solution phase conductive graphene sheets are… more
Abstract:DESCRIPTION (provided by applicant): Tumor microenvironment (TME) makes an essential contribution to tumor progression, recurrence, and metastasis. Currently, there is no standardized method to quantify major components of TME simultaneously, such as lymphovascular invasion, and to predict… more
Abstract:DESCRIPTION (provided by applicant): Chest pain in patients presenting to the emergency department (ED) present a clinical dilemma: transfer for emergent coronary revascularization, admit overnight for cardiac telemetry and stress testing, or discharge home with medical follow-up. In this proposal,… more
Abstract:Portable Brain Injury Biomarker Detection System with Integrated Microdialysis Probe Project Summary: SFC Fluidics is developing a portable, fully-integrated and automated medical device for clinical monitoring of patients with severe brain injury. The instrument will allow for automated detection… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project addresses the need for affordable compostable plastics to replace petroleum-based plastics. Plastic bags are an environmental eyesore that pollute waterways and kill wildlife. Local governments are now passing laws to ban the use of… more
Abstract:DESCRIPTION (provided by applicant): The long-term goal of this project is to develop an effective protein replacement therapeutic (PRT) for patients affected with rare forms of Osteogenesis imperfecta, OI-VIII (deficiency in prolyl 3-hydroxylase 1; P3H1)and OI-VII (deficiency in cartilage… more
Abstract:DESCRIPTION (provided by applicant): The goal of this proposal is to develop an effective enzyme replacement therapy (ERT) for patients suffering from GM1 Gangliosidosis by integrating a novel protein fusion ERT cell delivery strategy under development atBioStrategies LC and by exploiting safety,… more
Abstract:The long-term goal of this project is to develop an improved enzyme replacement therapeutic (ERT) for MPS I that integrates safety and cost advantages of plant-based bioproduction with innovations that enhance ERT delivery and disease correction. MPS I (encompassing Hurler, Hurler/Scheie, Scheie… more
Abstract:DESCRIPTION (provided by applicant): There are currently mutations in over 200 genes that have been described to cause kidney disease. Current strategies for diagnosis of genetic kidney disease are extremely costly and time consuming. We aim to develop a comprehensive next generation sequencing… more
Abstract:ABSTRACT: Silicon-based lasers/detectors have long been desired for owing to the possibility of monolithic integration of photonics with high-speed Si electronics and the aspiration of broadening the reach of Si technology by expanding its functionalities well beyond electronics. The goal of this… more
Abstract:Arkansas produces 80 percent of all the baitfish in the US and annually exports more than 6 billion baitfish nationwide. However, baitfish farmers have suffered from a productivity reduction due to serious fish losses resulting from interminable predation and extensive inventory control in… more
Abstract:This proposal will serve as a pilot project for poor, rural, Southern counties with rich forestry resources. Arkansas and surrounding states have some of the highest poverty rates in the nation. Arkansas 19 million acres of forests represent more than half of the total land mass of this state. This… more
Abstract:DESCRIPTION (provided by applicant): The goal of this proposal is to develop an effective enzyme replacement therapy (ERT) for Sanfilippo A patients by exploiting safety, supply, and cost advantages of plant-based enzyme bioproduction while integrating novel ERT delivery strategies being development… more
Abstract:SiC power semiconductors have the capability of greatly outperforming Si-based power devices. Smaller switching and on-state losses coupled with higher voltage blocking capability, and especially its high operating temperature make SiC the ideal semiconductor for high performance, high power density… more
Abstract:This SBIR Phase I project seeks to develop an advanced, flexible, robust, high-power density, high-voltage (600 V), solid-state circuit protection device (SSCPD) through the incorporation of silicon carbide (SiC) device technology, the implementation of advanced power packaging, and novel fault… more
Abstract:Arkansas Power Electronics International, Inc. (APEI, Inc.), and Moog, Inc. have allied to form a team devoted to the development of an intelligent, multi-channel, highly-miniaturized, high-temperature, Silicon Carbide (SiC) based Solid-State Energy Distribution Unit (SSEDU) to support emerging More… more
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