Abstract:DESCRIPTION (provided by applicant): This NIH SBIR project intends to develop three product lines of near infrared (NIR) bio-medical labeling reagents based on semiconductor nanocrystals (NIR NanoLabels), including conventional core/shell nanocrystals, type-II core/shell nanocrystals, and quantum… more
Abstract:This Phase II proposes to develop an innovative nanostructured coating, with a unique integration of hard phases and lubrication phases, for dry machining of austenite steels for the automotive and aerospace industries. This novel coating will be synthesized using a combination of electrostatic… more
Abstract:DESCRIPTION (provided by applicant): It is proposed to develop a nanoparticle coating of hydroxyapatite (HAp) on titanium dental implants. Osseointegration is of critical importance in dental implant surgical operation because it is affected by the proper selection of construction materials, design,… more
Abstract:We have developed an innovative lensless optical power limiting system for green region exploiting photoanisotropy of azobenzene films for low power continuous wave and high power nanosecond pulsed lasers (also with picosecond in solutions). It is a promising technique for next generation laser eye… more
Abstract:This NASA SBIR project will develop modular spray-cooled assemblies that satisfy NASA power and mass budgets and can be scaled to cool multiple heat sources subjected to high heat fluxes and microgravity conditions. Much of the work on spray cooling has been experimental in nature and technological… more
Abstract:SFC Fluidics in coordination with the University of Arkansas proposes to develop an immunoassay based lab-on-a-chip using the advantages of self-contained microelectrochemical detection and redox magnetohydrodynamic (MHD) microfluidics for the rapid detection of biomarkers of traumatic brain injury… more
Abstract:Space Photonics proposes a miniature, low power, high speed, optical communications turret utilizing a unique system design requiring no gimballing. This technology and design enables optical communications turrets specifically for unmanned aerial vehicle (UAV) and other airborne vehicle… more
Abstract:The Managed FPGA is a system component that contains a Field Programmable Gate Array (FPGA), System-on-a-Chip (SoC), and security features, packaged within a Multichip Module (MCM), that make this enhanced FPGA a sustainable, upgradeable component for use in DoD applications. Innovations include… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project aims to develop an automated instrument for rapid and specific detection of waterborne pathogens in municipal water supplies using methods combining immunoassay with electrochemistry. Although the disposable cartridges for this… more
Abstract:Cryptosporidium parvum, a protozoan parasite that invades the gastrointestial system, is a serious threat to the nation's water supply. Assays for pathogen using self-contained microelectrochemical detection are desirable because precise detection can be performed with simple instrumentation on… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will use a novel self-contained micro-electrochemical detection technology to measure the human protein response to specific biological agents. The end result will be an embedded computer controlled, automated, hand held device that… more
Abstract:DESCRIPTION (provided by applicant): Pig-to-human xenotransplantation may alleviate the critical shortage of organs available for transplantation. However, hyperacute rejection (HAR), acute vascular rejection (AVR), and cell-mediated rejection pose significant immunological hurdles to making… more
Abstract:Although biocontrol technology, including mycoherbicides, has been investigated for a long period of time, few products have actually made it into the commercial loop. The reasons for this are varied and include unfavorable environmental conditions, small markets and poor shelf-life. The test… more
Abstract:This Small Business Innovation Research (SBIR) Phase II research project will develop highly miniaturized power converters by developing a functional, scaled-down hardware prototype of a high-temperature multichip power module (MCPM). To achieve this goal, the company has taken advantages of the key… more
Abstract:This Phase II SBIR proposal seeks to develop high-temperature electronics by integrating motor drive control and SiC power electronics into a single, compact, highly efficient, reliable, high power density multichip power module (MCPM). Phase II will build upon the Phase I "proof of concept"… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will develop a portable, rapid and specific capillary channel based immuno-sensing system for food pathogens. The tests will be able to detect concentrations of
Abstract:This Small Business Innovation Research (SBIlR) Phase I project will develop a portable device for oxygenating streams and other surface water bodies using a combination of aeration and Dissolved Air Flotation (DAF), a process often used in settling tanks.
The commercial application of this… more
Abstract:75874-Fossil fuel combustion provides most of the world¿s energy needs, as well as most of the CO2 that is accumulating in the upper atmosphere with implications for serious global warming. With increasing energy demands, methods to sequester this by-product CO2 must be developed. This project… more
Abstract:This Small Business Innovation Research (SBIR)Phase I project project proposes to determine the feasibility of a software-modeling tool for the food industry to ensure safety of ready-to-eat (RTE) foods. Contamination of RTE foods has caused severe illnesses and major product recalls in recent years… more
Abstract:DESCRIPTION (provided by applicant):
The goal of this combination Phase I / Phase II STTR project is to test the hypothesis that anti-drug monoclonal antibodies are a safe and effective therapy for the medical problems associated with phencyclidine (PCP) abuse. There are currently no specific… more
Abstract:DESCRIPTION (provided by applicant): Commercial speech recognition software offers many people with physical limitations an important computer access method. While this access method is reasonably reliable for people with typical speech, people with motor speech disorders (dysarthria) are presently… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project addresses fabrication of micro- and nano-machined silicon gas diffusion electrodes (GDEs) for miniaturized Proton Exchange Membrane (PEM) fuel cells. Novel micro- and nano-machining techniques will enable application of… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will advance the performance of light emitting diodes based on semiconductor nanocrystals (NanoLEDs) to the same level of that of organic/polymer light emitting diodes (OLEDs). The key parameters of NanoLEDs targeted for this… more
Abstract:This Phase II proposal aims to develop nanocrystal-based technologies for the fabrication of nano-engineered solar cells with high specific power efficiency. The multiple-step fabrication will be completely based on solution-based procedures because of use of nanocrystal precursors. This warrants… more
Abstract:DESCRIPTION (provided by applicant):
This SBIR proposal intends to prepare luminescent anti-PSA (prostate specific antigen) single chain antibody fragment (scFv) -- Quantum Dot (QD) conjugates that can be used for PSA immunoassays. This project will be built on our recent success in preparing… more
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