Abstract:DESCRIPTION (provided by applicant): This feasibility project investigates whether people with complex communication needs can control the prosody of a text-to-speech synthesizer within a unique speech-aware word prediction program. The research team will
design a second-generation speech… more
Abstract:DESCRIPTION (provided by applicant): There is an urgent need for speech generating devices that meet the needs of young children with complex communication needs. The proposed project responds to this need by developing innovative software that will: (a)
appeal to young children by integrating… more
Abstract:DESCRIPTION (provided by applicant): The access options for people with disabilities who rely on their hands to control an assistive device have not improved in many years. The proposed project creates a new input method for assistive devices in which the
size, shape, and function of the access… more
Abstract:DESCRIPTION (provided by applicant): Semiconductor nanocrystals (quantum dots), specifically CdS, CdSe and CdTe, etc, have been extensively studied in the past two decades, leading to their integration in light emitting diodes (LEDs), solar cell, and bio-i
maging/labeling. Although efficient… more
Abstract:DESCRIPTION (provided by applicant): The proposed Phase I SBIR project is to show the feasibility of developing an affordable commercial instrument that provides laminar-flow fluidic interfaces to cell cultures at multiple coordinates in real time. The ins
trument will satisfy a growing, unmet need… more
Abstract:This Small Business Technology Research (SBIR) Phase I project will demonstrate a spectral down-converter based on metal ion-doped nanocrystalline quantum dots to increase the efficiency of polycrystalline silicon solar cells. Attempts to add a luminescent spectral down-conversion layer to… more
Abstract:DESCRIPTION (provided by applicant): This SBIR Phase II program aims to develop a novel class of commercial products of near infrared (NIR) nanolabels based on colloidal non-cadmium quantum dots, InAs/InP/ZnSe core/shell/shell dots coated with dendron liga
nds. NIR emitters are outstanding… more
Abstract:DESCRIPTION (provided by applicant): Nanomaterials and Nanofabrication Laboratories Program Announcement No. PA-08-050 (NN-Labs, LLC) Title: Near Infrared Semiconductor Nanocrystal for Imaging Guided Surgery Principal Investigator: Tiecheng Qiao Summary Th
e incidence of brain metastasis in patients… more
Abstract:To facilitate combat operations and maintain adequate force protection, there is an immediate need for all-around body armor systems for US military forces. This need has driven advancement in developing, evaluating, modifying, and incorporating new and commercial protective materials and… more
Abstract:Problem: This project will demonstrate the applicability of using rice bran and rice bran extract as a commercial scale growth medium for yeast. Currently, the production of yeast is carried out on a high sugar starting medium composed of beet or cane molasses, both of which are in short supply and… more
Abstract:DESCRIPTION (provided by applicant): NIH Phase I Quantum dots and Magnetic nano-particles for Ante-mortem Diagnostics of m Prion Infection Ocean Nano Tech proposes to develop a portable, rapid, sensitive, high throughput, inexpensive, and easy to use syste
m for the ante-mortem diagnosis of prion… more
Abstract:DESCRIPTION (provided by applicant): The presence of Her-2, estrogen receptor (ER) or progesterone receptor (P) on breast cancer cells is a very important biomarker which facilitates physicians in making decisions on treatment schemes and in proposing prog
nosis of the disease. Current methods for… more
Abstract:DESCRIPTION (provided by applicant): This NIH SBIR project intends to develop a new generation of iron oxide nanoparticles as target specific MRI contrast agents for early detection of breast cancer. Recent advances in iron oxide synthesis in organic solve
nts at elevated reaction temperature allow… more
Abstract:DESCRIPTION (provided by applicant): The goal of this SBIR project is to develop a multiplexing method to simultaneously quantify the expression levels of biomarkers in heterogeneous tumor tissue. The current method for diagnostic and prognostic classifica
tions of biomarkers is based on… more
Abstract:This Small Business Innovation Research (SBIR) Phase II research project focuses on the development of a product line of miniature pumping systems for the controlled delivery of fluids in ultra-low flow rate range (nanoliters to microliters per minute). This line of micropump systems will provide… more
Abstract:This Phase I SBIR proposal seeks funding to develop a radiation-hardened circuit architecture to achieve SEU and SEL immunity by using delay-insensitive asynchronous logic, and to demonstrate its feasibility, effectiveness, and efficiency. Further, early studies reveal that an operational… more
Abstract:DESCRIPTION (provided by applicant): The main goal of this Phase I SBIR project is to optimize the fabrication process and demonstrate the feasibility of using a novel carbon-based nanopipette (CNP electroprobe) for penetration of cell membrane in single c
ells with minimal cell intrusion and allow… more
Abstract:DESCRIPTION (provided by applicant): Vegrandis proposes to develop a rapid, sensitive, high throughput, inexpensive, and easy to use system for the ante-mortem diagnosis of prion infection. The proposed system offers a fully automated equipment with a disp
osable microelectrochemical cartridge for… more
Abstract:DESCRIPTION (provided by applicant): The ultimate goal of this STTR proposal is to develop a rapid, sensitive, and specific diagnostic test that can identify acetaminophen (APAP) protein adducts in human sera. APAP toxicity is the most common cause of acut
e liver failure (ALF) in the United States… more
Abstract:DESCRIPTION (provided by applicant): It is proposed to develop a target for production of iodine-124 for commercial distribution and to develop a radiolabeling business for I-124 radiotracers. I-124 is an increasingly useful nuclide for positron emission t
omography, especially to label molecules,… more
Abstract:The objective of this proposal is to develop multi-echelon logistics management tools based on Agile principles and integrate them into the Manufacturing Repair Overhaul (MRO) environment. The Oklahoma City Air Logistics Center (OC-ALC) current processes are sub-optimized and focus on each… more
Abstract:The objective of this proposal is to develop inventory flow tools based on Just In Time (JIT) principles and integrate them into the Manufacturing Repair Overhaul (MRO) environment. The Oklahoma City Air Logistics Center (OC-ALC) current processes vary greatly based on the specific needs of an… more
Abstract:APEI, Inc. is proposing to develop a low profile, non-intrusive, high temperature (300 degrees C) bearing data transmitter system that will allow the in-situ monitoring and diagnostic of bearing health. The proposed high-temperature data transmitter system will be built on high temperature… more
Abstract:Advances in radar systems are pushing the limits of present radar power supply technology. To enable new concepts, such as active array radar systems, significant improvements (i.e., power densities >200 W/in3, efficiency > 90%, transient response < 10 s, etc.) in radar power supply technology is… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project seeks to develop an advanced flexible self-powered robust high power density solid-state circuit breaker (SSCB) through the incorporation of emerging silicon carbide (SiC) device technology and the implementation of advanced thermal… more
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