Abstract:DESCRIPTION (provided by applicant): In this Phase I SBIR project, we shall show the feasibility of a unique, patent pending method to differentiate benign lesions such as moles (benign and dysplastic nevi) or liver spots (lentigenes solaris), from maligna
nt ones, such as lentigenes maligna and… more
Abstract:DESCRIPTION (provided by applicant): The proposed research may offer people who rely on assistive technology an exceptionally efficient method for entering words into computers and other assistive devices. We accomplish this by designing an on-screen keybo
ard that uses gesture- enhanced word… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will develop highly bright and stable doped nanocrystal/polymer nanocomposite thin film as light up-converting medium for infrared light visualization applications. Upconversion of higher energy light from lower energy radiation are… more
Abstract:There is immediate need for a new generation of scintillation materials for nuclear physics research, high-energy radiation (x- and gamma-rays) screening/imaging, and passive detection of nuclear materials with improved quality and low production cost. Inorganic scintillators have high output… more
Abstract:There is growing concern about how to limit the release of mercury into the environment. One significant source of mercury is found in fluorescent lamps. Recently, however, compact fluorescent lamps have been heavily promoted in order to conserve electrical energy. While it is true that switching to… more
Abstract:DESCRIPTION (provided by applicant): This SBIR Phase I project intends to develop a novel nanotechnology for low-cost commercial production of deoxyribonucleoside triphosphates by conjugating all three enzymes with superparamagnetic nanocrystals (Nano-Enzy
mes). Deoxiribonucleoside triphosphates,… more
Abstract:High-loading carbon nanotubes (CNTs)-based composites have found considerable application potentials in military. A key area of interest to Navy is unmanned vehicles that include air, ground, and sea platforms. However, the challenges in dispersing CNTs hind the development of such a composite in… more
Abstract:This Small Business Technology Transfer Phase I research demonstrates the feasibility to use the new generation of oxide magnetic nanoparticles for rapid and high efficient separation of foodborne pathogens. Rapid detection of foodborne pathogens is urgently needed to ensure food safety and security… more
Abstract:DESCRIPTION (provided by applicant): Since semiconductor nanocrystals [quantum dots (QDs)] have been adopted as a new class of fluorescent labels, many studies have indicated a broad range of potential applications using QDs as new probes in vivo and in vi
tro imaging. Because of QDs long lifetimes… more
Abstract:This NSF Small Business Innovation Research Phase II project is to synthesize cadmium-free, water-soluble, and multicolor quantum dots (QDs) by chemical doping. The project will focus on the synthesis of high quality doped ZnSe QDs using a newly developed phosphine-free approach. From these cadmium… more
Abstract:DESCRIPTION (provided by applicant): Enriched abnormal cells will enable genomic, proteomic, and epigenomic analyses to detect cancer-specific alterations in expressed genes, protein/peptide profiles, and epigenetic markers. The ability to carry out such e
nrichment in high efficiency in a routine… more
Abstract:DESCRIPTION (provided by applicant): Enriched abnormal exfoliated cells and biomolecules will enable genomic, proteomic, and epigenomic analyses to detect cancer-specific alterations in expressed genes, protein/peptide profiles, and epigenetic markers. The
ability to carry out such enrichment and… more
Abstract:Iron oxide magnetic nanoparticles with high magnetization value and well controlled size and surface chemistry are currently under intense study due to their broad applications in biomedical research. Recent advances in iron oxide synthesis in organic solv ents at elevated reaction temperature… more
Abstract:This STTR Phase II research project develops a circular chemical separation system on a small (~1 inch x 1 inch) chip. This chip and the associated instrument will separate complex mixtures for biological, chemical, medical, and industrial applications. Based on magnetohydrodynamic (MHD)-driven… more
Abstract:This Small Business Innovation Research Phase I research proposal targets technical innovations that will advance the implementation of micro-scale bioassays, lab-on-a-chip applications, and electrospray mass spectrometry approaches to proteomics. It is proposed to design and fabricate miniature,… more
Abstract:This Phase II SBIR Proposal develops a suite of labs-on-a-chip that can be used to establish the metabolic health of an individual in real-time from a finger-prick sample of blood. Each disposable chip will contain all reagents necessary to run the assay and all waste will be stored on the chip.… more
Abstract:In order to realize the geolocation and attitude determination benefits of formation flying multi-spacecraft clusters or constellations with onboard Acquisition, Tracking and Pointing (ATP) lasercom systems, four key elements must be present: 1. Broadband inter-spacecraft communications to enable… more
Abstract:This Small Business Technology Transfer Phase I project applies newly developed technology to construct a smart Self-Assembled Monolayer (SAM) for the rapid detection of Paralytic Shellfish Toxins, (PSTs), which are neurotoxic seafood poisons produced by algae then accumulated in filter-feeding… more
Abstract:Power electronic converters are essential in every MDA vehicle, with use in critical systems ranging from electric power management applications, to power distribution, to on-board servo motor/actuator drivers. Advancing state-of-the-art power electronics technologies through the use of SiC… more
Abstract:The objective of this Small Business Innovation Research Phase I project is to develop an isolated bi-directional ac-dc PCM-4 using a novel multi-level modular design approach compatible with silicon carbide (SiC) power switches. The multi-level PCM Module will allow for the design of power-dense,… more
Abstract:In this Small Business Innovation Research project, APEI, Inc. and TRS Technologies are partnering to develop rad-hard high density DC/DC power converters functional to temperatures in excess of 300 degreesC. Expert utilization of the now emerging silicon carbide (SiC) power devices will allow for… more
Abstract:In Phase I, the research team formed by APEI, Inc. and University of Arkansas proved the feasibility of developing ultra-wide temperature (-230 oC to +130 oC) motor drives utilizing silicon-germanium (SiGe) asynchronous logic digital control electronics by the successful design… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will develop and commercialize silicon carbide (SiC) based radio frequency (RF) transmitters for high-temperature environments. The team will prove the feasibility of the concept and design through the successful demonstration of a SiC… more
Abstract:Profit margins in commercial catfish production continue to shrink due to increased production costs, economic inflation, and increased foreign competition. In order to compete, catfish producers must become more efficient. Research has shown that progeny resulting from the hybridization of channel… more
Abstract:This Small Business Technology Transfer (STTR) Phase I project demonstrates the feasibility for the development of an innovative biosensor system for rapid and sensitive detection of viable foodborne pathogens. The core technology of the proposed system is to introduce a genetically engineered… more
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