Abstract:The submarine community"s critical need for advanced payload and expanded flight-envelop capable small Unmanned Aircraft Systems (UAS) is stalled by current tube launched UAS which have low endurance with low performance Intelligence, Surveillance, and Reconnaissance (ISR) packages.… more
Abstract:DESCRIPTION (provided by applicant): miRNA biomarkers related to Alzheimer's disease (AD) that may be useful as a diagnostic tool or in elucidating the mechanisms of disease and discovery of novel therapeutics will be identified using a novel whole transcriptome qBead X-MAP-based assay (not… more
Abstract:ABSTRACT: The current designs of telescopes for space borne applications use monolithic glass, beryllium, or silicon-carbide optics. With that existing optical technology, it is increasingly difficult or impossible to meet the new goals and requirements of AF, ORS, and other modern DoD missions. … more
Abstract:The motivation of the proposed SBIR is to develop, demonstrate and commercialize a compact, low-mass, high output power (1-10 milliwatt), tunable source of CW THz radiation operating at room temperature. The source will be useful both as a narrow band frequency stable sources for driving heterodyne… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project aims to demonstrate a high-performance spin torque magnetoresistive random access memory (ST-MRAM). ST-MRAM technology promises a powerful combination of non-volatility, high density, high speed, and low power. The major impediment to… more
Abstract:We will develop new computational techniques to extend the reach of large ground-based optical systems, enabling high resolution imaging of satellites under daylight conditions. Current state-of-the-art systems, such as the 3.6 m AEOS telescope, dramatically underperform in such conditions because… more
Abstract:DESCRIPTION (provided by applicant): Poly(ADP-ribosyl)ation is a post-translational modification that plays a central role in the regulation of cell death and DNA repair. PAR serves as a surrogate marker for poly(ADP-ribose) polymerase (PARP) and poly(ADP-ribose) glycohydrolase (PARG), which are… more
Abstract:DESCRIPTION (provided by applicant): Approximately 518 kinases are encoded by the human genome and serve as critical mediators of signal transduction brought about by a phosphorylation event. Many kinases are known to be involved in diabetes, inflammation,cardiovascular diseases, tumor cell… more
Abstract:Tactical Generators are profuse consumers of fuel. As the generators wear, fuel consumption increases. Increases in fuel consumption mean more logistics demand and delivery of fuel through potentially hostile areas to forward tactical bases represents an operational challenge. Sustainment of Army… more
Abstract:ABSTRACT: We are experiencing grand challenges to ensure that cyberspace resources and services can effectively tolerate epidemic-style cybperattacks, and manage automatically its resources and services. Currently, there are no effective commercial technologies to secure and protect cyberspace… more
Abstract:Advances in Internet services and mobile wireless services will lead to the development of cyberspace services that are pervasive and ubiquitous and touch all aspects of our life. However, along with these advances, we are experiencing grand challenges to secure and protect our cyberspace resources… more
Abstract:This proposal sets forth a precise and rapid methodology for identifying the interaction sites between monoclonal antibodies and proteins. The basis of the system is a high-throughput mass spectrometry-based analysis of epitope determinants to identify theinteracting protein sequences using… more
Abstract:This proposal describes an approach to establishing a Navy mission planning application marketplace and associated governance so the Navy may benefit from easily accessible open-market competition for mission planning applications. Ideally suited as an service application baseline, Kutta's UGCS… more
Abstract:UAVs are well suited for the resupply mission, reducing risk to human air crews and allowing more sorties (number of pilots and physical human requirements are currently limiters). Current users of a UAV systems must be trained and maintain domain specific knowledge regarding UAV operations (flight… more
Abstract:Given the constraints associated with current airborne host platforms, a technological solution is needed for efficiently obtaining meteorological data at targeted locations and altitudes. A combination of using manned and unmanned aircraft with guided dropsondes is a promising and achievable path… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will help develop the first effective therapy for late stage hormone refractory Prostate Cancer (PCa). These late stage tumors rely on the Androgen Receptor (AR) pathway, but do not require androgen. Genetic changes allow tumors to use… more
Abstract:ABSTRACT: The key objective of the proposal is to develop sophisticated, graphical user interface driven software tools built on fully microscopic physics to design, guide and provide feedback on growth, fabrication and evaluation of semiconductor structures that provide optical gain in the… more
Abstract:This proposal is for the development of an innovative, high power, and extremely reliable 1.26-micron Ho-doped fluoride fiber amplifier. The proposed fiber amplifier consists of a Ho-doped fluoride fiber pre-amplifier and power amplifier. Laser at 1187 nm will be used as a resonant pump laser… more
Abstract:We propose an all-fiber based 2.05-micron single frequency, narrow linewidth seeder laser with 10 nm tuning range and 5GHz frequency modulation for next generation LIDAR system. Highly Tm-doped fiber laser is used as a resonant pump source in order to reduce the phase noise and laser linewidth. An… more
Abstract:For NASA's various types of coherent LIDAR applications, NP Photonics propose to develop a 50 mJ monolithic 2 micron pulsed fiber laser transmitter in 200 ns regime with transform-limited linewidth, leveraging on NP's proprietary germanate active fibers. NP's patented large core SM PM… more
Abstract:NP Photonics proposes to develop an ultra-stable, compact, and highly reliable deep ultraviolet (UV) laser source for Raman spectroscopy. For this, we will draw on NP Photonics"long experience with the commercialization of single-frequency fiber lasers and amplifiers. In cooperation with the… more
Abstract:ABSTRACT: We propose to develop a light weight, compact, vibration-less and micro-scale cooler for space-mission conditions based on optical refrigeration using an all-fiber approach. Specifically, we will use a Tm+3-doped fiber laser to pump Tm+3-doped glass fibers, which provide the cooling… more
Abstract:We propose to develop numerical methodologies that can be used as alternatives to standard finite-difference time-domain algorithms, and that will offer substantial reductions in numerical complexity (notably CPU-time requirements) without the need to trade-off flexibility for overall robustness. In… more
Abstract:This Phase II Proposal is for the development of an all-fiber based approach to optical cooling for RF systems: a high power, high efficiency Tm+3-doped fiber laser (Lambda from 1.9 microns to ~ 2 microns) is used to pump Tm+3-doped glass fibers, which provide the cooling action on the affixed heat… more
Abstract:ABSTRACT: NP Photonics has developed high power single frequency narrow linewidth 1550nm and 1064nm fiber laser products for LIDAR, sensing, and telecommunications. The fiber laser incorporates proprietary fiber technology developed at NP Photonics. Current state-of-art technologies have been… more
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