Abstract:ABSTRACT: Unmanned Aerial Vehicles (UAV) have been the most dynamic growth sector of the aerospace industry this decade and it is projected to double over the next decade. The most significant catalyst has been the enormous growth of interest in UAVs by the US military, tied to operations in Iraq… more
Abstract:DESCRIPTION (provided by applicant): Alcohol-related problems in older Americans are a growing public health concern. About half of all older adults drink alcohol, and many drink above recommended limits. In the elderly, changes in the body's ability to metabolize alcohol mean that even… more
Abstract:DESCRIPTION (provided by applicant): Tumor necrosis factor (TNF)-alpha plays a pro-inflammatory role in aging-related neurodegenerative diseases, such as Alzheimer's disease or Parkinson's disease. The biologic TNF inhibitors (TNFI), such as the TNF decoyreceptor, cannot be developed for… more
Abstract:DESCRIPTION (provided by applicant): Metachromatic Leukodystrophy or MLD, is a genetic disease that affects the lysosomal enzyme, arylsulfatase A (ASA). People born with MLD develop extensive lysosomal storage product accumulation in tissues, including thebrain. Children with MLD develop multiple… more
Abstract:ABSTRACT: Liquid rocket engine (LRE) turbopumps operate in complex flow regimes that range from cavitating liquid flows in pumps to shock-containing compressible flows in turbine components. The unsteady flow phenomena seen by structural components establish design limitations associated with mean… more
Abstract:ATA Engineering, Inc., (ATA) proposes a Phase II SBIR program to demonstrate an innovative engine air-brake (EAB) technology that uses a deployable swirl vane mechanism to switch the operation of a turbofan engine nozzle from a conventional mode to a "drag management" mode. Equivalent drag… more
Abstract:Large, lightweight, deployable solar array structures have been identified as a key enabling technology for NASA with analysis and design of these structures being the top challenge in meeting the overall goals of the NASA Space Technology Roadmap. The use of analysis to drive design from an early… more
Abstract:ABSTRACT: This SBIR program seeks to more accurately evaluate the unsteady aerodynamics on the weapons bay door due to the weapons bay, transient surface motions, and fluid-structure interaction. The goal of the program is to develop a methodology that will allow the unsteady aerodynamic loads on… more
Abstract:ATA Engineering, Inc. proposes to advance the current state-of-the-art composite analysis techniques to predict laminate properties from limited ply-level material property data with an innovative approach to composite failure analysis. The SBIR will develop a stochastic approach to address… more
Abstract:ABSTRACT: The proposed research will develop a method of compensating atmospheric disturbances in the transmitting subapertures of a phased array transceiver operating in the infrared. The aero-optical boundary layer and atmospheric turbulence create phase variations within each subaperture. To… more
Abstract:DESCRIPTION (provided by applicant): The broad long-term of this project is to develop methods for evaluation of adherence to intravaginal microbicide therapy for the prevention of HIV transmission. Correct determination of adherence to preventative therapies in clinical trials is essential to… more
Abstract:DESCRIPTION (provided by applicant): The long term goal of this project is to prevent HIV transmission. Using the drug delivery platform we developed for the ganciclovir intraocular implant, Vitrasert(R), we propose to develop an intravaginal ring microbicide formulation releasing the antiretroviral… more
Abstract:DESCRIPTION (provided by applicant): The broad long-term goal of this research is to reduce morbidity due to arthritis by developing long-lasting injectable intra-articular drug delivery systems. Intra-articular steroids have been a mainstay of treatment for arthritis for more than 50 years. However… more
Abstract:ABSTRACT: The proposed Phase II effort is a two year program focused on demonstrating both the feasibility of an integrated semiconductor optical thresholder and its ability to enable a high frequency Optical Analog to Digital Converter (OADC). Such OADCs would dramatically enhance capability in… more
Abstract:DESCRIPTION (provided by applicant): The development of addiction involves the dopaminergic reward pathway and downstream negative changes that lead to craving and repeat self-administration. While it is clear this process involves changes in neuronal plasticity t the synapse junction, the exact… more
Abstract:DESCRIPTION (provided by applicant): Monoclonal antibodies targeting tumor associated antigens (TAA's) have since 1997, provided safe and efficacious human cancer therapeutics. More recently, bispecific antibodies or bispecific antibody fragments that promote immunologic synapses between cells… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project seeks to address the significant technical barriers associated with an untethered overground cooperative gait rehabilitation exoskeleton. Current gait rehabilitation techniques available to patients with gait abnormalities include… more
Abstract:With this Phase I SBIR project we intend to develop technical solutions to the primary issues limiting the feasibility of a stand-alone real-time balance feedback device. We intend to develop a technique that uses multiple sensors to estimate the orientation of the user"s body segments in the… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will build a real-time detection instrument for conformational change. Conformational change is a change in the structure of a biomolecule such as a protein. For a given protein, different structural changes produce different… more
Abstract:Thermal injury is common in military conflicts due to primarily to the widespread use of explosive devices. Burns can produce scars that are excessive, physically debilitating and functionally damaging. There is a critical need for an effective product that can control bacterial contamination and… more
Abstract:DESCRIPTION (provided by applicant): Thick hyperviscous mucus and delayed mucociliary clearance are important elements underlying cystic fibrosis (CF) pathogenesis, but currently available therapeutics exhibit limited efficacy to combat mucus stasis. In addition, biofilms that populate the CF lung… more
Abstract:This Small Business Innovation Research Phase II project addresses the need for new widespread datasets to help reduce uncertainties in current predictions of climate change and to improve our understanding of the health impacts of air pollutants. The development of a new, compact instrumentation… more
Abstract:Wideband Code Division Multiple Access (WCDMA) is the most recent generation of cellular phone technology that is being adopted for commercial, government, and military mission critical systems. One of the key enablers towards adoption of cellular technology in tactical environments is Mobile User… more
Abstract:Military networks are composed of mobile nodes with different, often highly specialized mission functions and capabilities. But node mobility in a noisy, often-obstructed, adversarial communications environment causes nodes to lose contact with the network frequently and unpredictably. This SBIR… more
Abstract:ABSTRACT: Space-based space situational awareness (SSA) for the surveillance and reconnaissance of deep space (DS) resident space objects (RSOs) requires advanced compression algorithms. Due to downlink availability and bandwidth limitations, gross loss compression is performed prior to… more
There are several categories such as “By Agency”, “By Year”, “By State” etc.
Select a checkbox within a category to refine your search results.
Each of your selections is listed in the “Narrow Search Filters” bar. You can uncheck these selections to remove them.
Search for Either Criteria
When you select multiple values within a category, the results will include values that match either of the selections.
For example, selecting “2005” and “2007” in the “By Year” category will display results that include either 2005 OR 2007 in the results.
Narrowing the Search Results
You can refine your search results across categories. To narrow down your results, select multiple values across different categories. The results will only include values that match the selections across the categories.
For example, selecting “2005” in the “By Year” category and “NASA” in the “By Agency” category will only display the results that contain both “2005” AND “NASA” in the results.