Abstract:DESCRIPTION: New therapeutic agents are urgently needed for the treatment of sickle cell disease (SCD), the world's most common genetic disease. Our long-term goal is to develop a drug for use in children that prevents the inexorable progression of SCD. SCD affects approximately 100,000 people… more
Abstract:DESCRIPTION (provided by applicant): New therapeutic agents are urgently needed for the treatment of sickle cell disease (SCD), the world's most common genetic disease. Our long-term goal is to develop a botanical drug for use in children that prevents theinexorable progression of SCD. SCD… more
Abstract:The feasibility of fusion as a practical energy source needs to be improved significantly by removing some of the restrictions that low-temperature superconductors put on the fusion magnet systems. One method to simplify the magnet system is by using high-temperature superconductors (HTS) that … more
Abstract:Accelerator magnets that are currently being used in high-energy physics experiments are limited to a maximum magnetic field of about 20 T because superconductivity in the low-temperature superconductors (LTS) from which the magnets are constructed breaks down at higher fields. The only way to build… more
Abstract:The feasibility for fusion as a practical energy source needs to be enhanced significantly by removing some of the restrictions that low-temperature superconductors put on the fusion magnet systems. This can be done by using high-temperature superconductors, allowing for much larger temperature… more
Abstract:The objective of this proposal is to demonstrate a set of methods for automatically extracting metadata from diverse data sets to serve as a common vocabulary by which data can easily be queried, retrieved and combined for visualization in a geobrowser. We propose extracting keyword tags from both… more
Abstract:Simulation tools that physically model daylight and electric lighting systems show promise in planning energy efficient lighting systems. There are still many barriers for these tools to reach the market. This research examines using bring high performance computing and user-centered design to the… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project aims to develop a micro-electro-mechanical system (MEMS)-based moisture (dew point) measurement instrument. Trace moisture measurements are needed in a variety of industrial sectors including natural gas production and distribution,… more
Abstract:In this SBIR Phase II contract, the contractor shall develop and test Smokescreen for research, specifically, manufacturing the custom genotyping array and software based on specifications gathered in Phase I, and testing and optimizing Smokescreen in diverse smoking-related research applications.… more
Abstract:The Elicitor tool developed under this SBIR will significantly reduce the time and manpower necessary to effectively elicit, characterize and analyze stakeholder needs. It will enable effective requirements generation and allocation to appropriate baselines, and it will reduce redundant efforts… more
Abstract:ABSTRACT: Legacy satellite command and control Front-End Processors (FEPs) are constructed using largely monolithic architectures, making deployed baseline changes difficult. This rigidity creates restrictions and limits current TT & C mission capability and prevents increases in data… more
Abstract:ABSTRACT: Air and space gimbaled Infrared, multi-spectral, and hyperspectral sensor systems require cryogenic cooling to operate. Current cryogenic systems are inefficient, costly, subject to vibrations, are typically the high-maintenance portion of a sensor system, and take up a considerable… more
Abstract:Miniaturized smart munitions are seeing increasing use across all branches of the Department of Defense (DoD) in order to meet the ever evolving mission needs for the U.S. warfighter. These smart micromuntions have been enabled by advances in capabilities and miniaturization of critical… more
Abstract:ABSTRACT: Adversarial installations, such as those housing the means for nuclear weapons production, are increasingly being constructed in heavily fortified locations and often using ultra high performance concrete (UHPC) as the construction material. As such, the U.S. Air Force has considerable… more
Abstract:ABSTRACT: In response to the U.S. Air Force"s need for fiber cooling and pointing in high power fiber amplifiers of 1kW and up, i2C Solutions propose the development of a conformal thermal ground plane (TGP) technology to interface with heat sinks integrated into the active precision pointing… more
Abstract:The innovation of sketch-based interaction for agile manufacturing substantially lowers the barrier to entry for novice engineers and designers. Low-cost rapid prototyping hardware -- 3-D printers and laser cutters -- offers tremendous educational potential, enabling students to personally design,… more
Abstract:DESCRIPTION (provided by applicant): While the number of diagnostic technologies available for adult applications continues to grow, there remains a paucity of technologies suitable for fetal evaluation. In particular, noninvasive assessment of fetal cardiac electrophysiology has not been routinely… more
Abstract:This Small Business Innovation Research Phase I project will investigate the commercial potential of flash-sintering to enhance the manufacturability and performance of Solid Oxide Fuel Cells (SOFCs). The co-sintering of heterogeneous multilayer ceramics remains a technical barrier to the… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project proposes to develop a cell-free optical enzymatic biosensor for monitoring trichloroethene (TCE) concentrations in water. The biosensing concept will be implemented in an optical fiber format, in which optical biosensor tips are linked… more
Abstract:ABSTRACT: Feature extraction and target recognition suffer from a lack of a reliable model for both exploitable target features and the electromagnetic signature they possess. Signature data are often hard to interpret and invert to recover the target robustly. Bayesian learning approaches to… more
Abstract:The Department of Energy has identified a need for low-cost, wireless, three-phase, true power sensors for commercial and industrial applications at a target cost of $20 per meter. The proposed work addresses the three largest cost drivers of existing power measurement solutions: (1) hardware cost… more
Abstract:ABSTRACT: The Braxton Ace Premier Intelligent Distributed Scheduler (AceIDS) prototype will demonstrate the feasibility of a distributed scheduling system capable of automatically optimizing ground communication resource allocation to space assets fusing electronically-generated routine and… more
Abstract:The overall technical goal of this SBIR is the development of a commercially viable, small Unmanned Aircraft System (sUAS) with a passive microwave sensor to enable high resolution mapping of soil moisture content. Current remote-sensing methods for sampling soil moisture often fail to provide… more
Abstract:The innovation is a compact, reliable, light weight, electrically driven pump capable of pumping cryogenic liquids, based on scroll pump technology. This pump will fulfill several needs stated in SBIR Research Topic, H2.01: Cryogenic Fluid Management Technologies. Zero gravity cryogenic control… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will further develop an all solid state lithium battery comprised of a sulfur-based solid-state electrolyte, a high capacity nanostructured cathode and a metal lithium alloy anode. The proposed program is based on research performed at… more
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