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Displaying 101 – 125 of 2514 Awards
Company: CIENCIA, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Polymicrobial infections are of great concern to the research community because they have a dramatic impact on the productivity research groups, on the reliability of experimental results, and on the progress that can be made in unraveling fundamental biological… more
Company: Connecticut Analytical Corporation Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: Dried blood spot (DBS) analysis has gained recognition in recent years in basic science and clinical diagnostics. This impetus relies upon its numerous advantages over the collection, transport and storage of blood samples obtained by conventional venipuncture. Although there is wide-spread interest… more
Company: BIORASIS, INC. Agency/Program/Year/Phase: NSF / SBIR / 2012 / 2
Abstract: This Small Business Innovation Research (SBIR) Phase II project aims to develop a wireless, needle implantable miniaturized (0.5 x 0.5 x 5 mm) sensor for continuous glucose monitoring, with provisions for internal self-calibration that ultimately eliminates the need for frequent, external… more
Company: Global Engineering and Materials, Inc. Agency/Program/Year/Phase: DOD / STTR / 2012 / 1
Abstract: A combined discrete cohesive interface fracture and continuum damage mechanics initiation and propagation toolkit for Abaqus will be developed for the residual strength prediction of adhesively bonded composite structures subjected to multi-axial loading. This tool will allow us, for the first time,… more
Company: Global Engineering and Materials, Inc. Agency/Program/Year/Phase: DOD / STTR / 2012 / 1
Abstract: Global Engineering and Materials, Inc. (GEM) along with its team members Northwestern University, Lockheed Martin, and Boeing Company, propose to develop an automatic software tool for 2D/3D fatigue crack growth prognosis of complicated structures under multi-axial loading. The XFAT toolkit will be… more
Company: Global Engineering and Materials, Inc. Agency/Program/Year/Phase: NASA / SBIR / 2012 / 2
Abstract: A Probabilistic Fatigue Damage Assessment Network (PFDAN) toolkit for Abaqus will be developed for probabilistic life management of a laminated composite structure with both microcracking induced stiffness degradation and cyclic loading induced delamination crack growth without remeshing. It is… more
Company: Global Engineering and Materials, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: A hybrid damage initiation and propagation toolkit for Abaqus will be developed for residual strength and life prediction of adhesively bonded composite structures. This tool will for the first time be able to simulate concurrently both the continuum and discrete damage based progressive failure… more
Company: Global Engineering and Materials, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 2
Abstract: ABSTRACT: A Hybrid Structure Evaluation and Fatigue Damage Assessment (HYSEFDA) toolkit for Abaqus will be developed for advanced hybrid structures under multi-axial and variable amplitude cyclic loading. The tool will be able to characterize arbitrary geometric configurations of fiber metal… more
Company: Global Engineering and Materials, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 2
Abstract: A fully coupled fire-structure interaction module will be developed and implemented within GEM"s Abaqus Fire Interface Simulator Toolkit (AFIST) for fire response prediction in aluminum ship structures. This enhanced AFIST will be able to characterize a 3D complex geometry where its topology is… more
Company: L2 DIAGNOSTICS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: DESCRIPTION (provided by applicant): The long-term product goal of this project is a small molecule therapeutic to treat rheumatoid arthritis (RA), which acts by reducing the inflammatory response triggered by the pro-inflammatory cytokine macrophage migration inhibitory factor (MIF). Since MIF is… more
Company: L2 DIAGNOSTICS, LLC Agency/Program/Year/Phase: HHS / STTR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): All forms of diabetes are characterized by the death of insulin producing cells. In Type 1 diabetes (T1D), this leads to the reliance on exogenous insulin for survival. In addition, there is cell loss in T2D and inindividuals who lose islet or pancreas… more
Company: L2 DIAGNOSTICS, LLC Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: Flaviviruses enter mammalian cells by a mechanism involving a structural rearrangement of the stem region of their envelope protein. The stem region establishes specific molecular contacts with amino acid residues of domain II of the rest of the envelope protein. Our hypothesis is that tetrapeptides… more
Company: L2 DIAGNOSTICS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Lyme disease, due to infection with the Ixodes tick-transmitted spirochete Borrelia burgdorferi, is the most common vector-borne disease in the United States, with over 38,000 confirmed and probable cases reported to the CDC in 2009. Spirochetes first establish… more
Company: L2 DIAGNOSTICS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): This is a proposal to test the feasibility of using triplex molecules for use as a therapeutic to correct Hurler Syndrome (HS). Lysosomal storage diseases (LSDs), such as HS, represent a diverse collection of monogenicdisorders that have devastating clinical… more
Company: LIFEPHARMS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Fungal infections continue to be a major cause of morbidity and mortality among HIV-infected patients. Many of the emerging fungal pathogens that are resistant to the three classes of antifungal agents for AID-s-relatedinfections are becoming more common and are… more
Company: MATERIALS TECHNOLOGIES CORPORATION Agency/Program/Year/Phase: NASA / SBIR / 2012 / 1
Abstract: The Exercise Load Measurement Insole (ELMI) is a system that is designed to measure normal and shear foot forces during exercise. The ELMI system is lightweight, portable, unobtrusive, and its versatility allows it to be used for many purposes outside of exercise load measurement and study. At the… more
Company: MATERIALS TECHNOLOGIES CORPORATION Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: Considerable research and development effort has been devoted to improving seating in helicopters since the early 1960s when the need for improved ergonomics and crashworthiness was first established. Yet currently a typical rotorcraft crew/pilot seat uses only passive shock absorbers for mediocre… more
Company: MATERIALS TECHNOLOGIES CORPORATION Agency/Program/Year/Phase: DOD / SBIR / 2012 / 2
Abstract: The overall goal of this Army SBIR program is to develop innovative solutions for mitigation of high-frequency rotor induced whole body vibration of seated occupants in helicopters while providing failsafe adaptive crash safety that surpasses the limited protection provided by the current… more
Company: Molecular Neuroimaging, L.l.c. Agency/Program/Year/Phase: HHS / STTR / 2012 / 2
Abstract: DESCRIPTION (provided by applicant): We propose to develop a software package to automatically evaluate a subject's beta amyloid PET scan (using either C11-PIB, F18-florbetaben, or F18-florbetapir, F18-flutemetamol) by normalizing the subject's scan, masking away non-gray matter tissue… more
Company: ODIS Agency/Program/Year/Phase: NASA / SBIR / 2012 / 2
Abstract: Optoelectronic integrated circuits offer radiation-hard solutions for satellite systems with much improved SWPB (size, weight, power and bandwidth). The phased array for sensing and data transfer is one system that optoelectronics can impact in the near term. It is known that optical delay could… more
Company: Omega-p, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2012 / 1
Abstract: The quest for deepened understanding of the origin of the universe requires continued search for elementary particles, for which high-energy accelerators are necessary tools. Reducing the size, complexity, and cost for future accelerators is essential if they are ever to be built. New technologies… more
Company: Omega-p, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2012 / 1
Abstract: The quest for deepened understanding of the origin of the universe requires continued search for elementary particles, for which high-energy accelerators are necessary tools. Reducing the size, complexity, and cost for future accelerators is essential if they are ever to be built. New technologies… more
Company: Real-Time Analyzers Agency/Program/Year/Phase: NSF / SBIR / 2012 / 1
Abstract: This Small Business Innovation Research Phase I project will demonstrate feasibility by developing a novel sampling system to detect 103-4 cfu/g Salmonella typhimurium in spinach within 2 hours. Foodborne diseases resulting from Campylobacter, Escherichia, Listeria, Salmonella, Shigella and Vibrio… more
Company: Real-Time Analyzers Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): The overall aim of this SBIR program is to develop a surface-enhanced Raman spectroscopy (SERS) based device for on-site analysis of drugs in saliva. This device will allow immediate assessment of both medicinal and illicit drug use by patients with… more
Company: Precision Combustion, Inc. Agency/Program/Year/Phase: NASA / STTR / 2012 / 1
Abstract: Current approaches planned for space suit atmosphere revitalization (AR) are neither compatible with each other nor regenerable in space, and have a high life cycle operating cost associated with them. The proposed PCI innovation in collaboration with University of Hartford involves synthesizing… more
Displaying 101 – 125 of 2514 Awards
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