Abstract:DESCRIPTION (provided by applicant): Treatment for head and neck squamous cell carcinoma (HNSCC) often confers considerable functional impairment. As a result, HNSCC patients experience significant decrements in quality of life, high levels of emotional distress, deteriorations in interpersonal… more
Abstract:DESCRIPTION (provided by applicant): healthEworks' mission is to improve discharge health education for the 100 million patients discharged from U.S. emergency departments (EDs) annually. healthEworks aims to accomplish this goal by creating and distributing Video Prescriptions - concise videos… more
Abstract:DESCRIPTION (provided by applicant): The overall goal of this application is to develop a quantitative in-vivo small animal imaging system for fluorescent reporter probes that fuses fluorescence light emitting computed tomography (FLECT) with X- ray comput
ed tomography (CT). The proposed… more
Abstract:DESCRIPTION (provided by applicant): The overall goal of this application is to develop a scalable production system for the manufacture of an adeno- associated virus (AAV) serotype 8-based gene therapy vector bearing a human low density lipoprotein recept
or (hLDLR) transgene for the treatment of… more
Abstract:This Phase I Technical Approach will provide the Government with an approach to identify, assess, and monitor the manner in which terrorist websites influence target audiences. Our approach is unique in that it applies psychological and sociological approaches to understanding the information and… more
Abstract:The objective of this research is to demonstrate the feasibility of developing a software toolkit to describe, define and create visual data models that can be dynamically linked into a spatial framework to facilitate more rapid understanding of complex data sets for leadership decision making. The… more
Abstract:Defense Group Inc. (DGI) proposes a unique approach to Cross Layer Modeling of JTRS MANETs. Our approach integrates admission control with congestion management schema. We propose a schema of "Intelligently" dropping packets with three possibilities for improved JTRS network throughput: 1) Using a… more
Abstract:DESCRIPTION (provided by applicant): The goal of the proposed research is to determine the feasibility of, and create prototype software for, a library of reusable synthetic biology components using Semantic Web technologies OWL, RDF, SPARQL and SWRL. Thislibrary will dramatically increase the… more
Abstract:DESCRIPTION (provided by applicant): Almost all human diseases have at least some environmental component. Even well- established genetic disorders do not often become manifest until adulthood, indicating at least some external influence on the pathologica
l phenotype. To increase awareness of… more
Abstract:While current Air Force logistics processes have served us well, and provided unparalleled support since the end of the Cold War, the need to significantly reduce costs while improving weapons system availability is essential. Senior Air Force officials have stated in numerous documents that the… more
Abstract:The objective of this project is to promote and realize improvements in readiness, sustainability and availability for US Air Force weapons systems and platforms. The centerpiece of Phase II is the primary set of process workflows which provide for the accomplishment of Supply Chain Management (SCM)… more
Abstract:The High Volatility Fuel Storage Module (HVF Module) prototype technology demonstrator will incorporate MDD"s Phase I preliminary design efforts with a Phase II, detailed engineering approach, to develop a unit that will support the Littoral Combat Ship (LCS) as a mission module. The HFV Module… more
Abstract:The objective of our proposed effort is to demonstrate the feasibility of an extremely rapid analysis of whole blood samples in non-laboratory environments using MEMS-based fabrication techniques combined with new developments in highly specific antibodies. We believe this technology will enable… more
Abstract:The overall goal of this project is to develop a flexible acuity sensor (FAS), including both hardware and software, and demonstrate its ability to acquire and track moving targets in the environment, including when the sensor itself is moving. These sensors will utilize a proprietary Centeye vision… more
Abstract:We propose to develop a commercially adequate, robust and perfomant OWL-based Integrity Constraint (IC) validation system with several innovations, including novel debugging and explanation support for data integrity errors; incremental and optimized validation of data integrity; and a unified… more
Abstract:DESCRIPTION (provided by applicant): Inhalants, which include aerosols, volatile liquids, gases, and nitrites, have found increasing use as mind-altering drugs especially among middle school- and high school-aged children. Inhalants have devastating effect
s on the nervous system, as well as the… more
Abstract:While current Air Force logistics processes have served us well, and provided unparalleled support since the end of the Cold War, the need to significantly reduce costs while improving weapons system availability is essential. Senior Air Force officials have stated in numerous documents that the Air… more
Abstract:The Littoral Reverse Osmosis Module (L-ROM) prototype technology demonstrator is a reverse osmosis water purification module for use in littoral and other waters having a high colloidal (inorganic and natural organic) matter. The principal challenge of this project is to design a system that will… more
Abstract:Jet engine titanium compressor airfoils are susceptible to erosion damage ranging from a few percent loss in blade chord length in fighter engines to more significant erosion exhibited by helicopter engines operating in desert environments. The application of titanium nitride coatings on individual… more
Abstract:We will develop "flexible sensing" techniques that will enable a single sensor to perform the functions of both a "seeker" and a "target detection device". One set of approaches will comprise resolution enhancement and other techniques to extract target identification and tracking information, as… more
Abstract:We propose to evaluate tree dominant semantics for description logic integrity constraints, as well as multiple proposals for adding syntax for integrity constraint axioms, to the Web Ontology Language standard, OWL. Further, we propose to implement a semantics, in the form of a syntax compiler and… more
Abstract:DESCRIPTION (provided by applicant): Human consumption of alcohol is ubiquitous. While it is reported that ninety percent of the population consumes various amounts of alcohol, only a small but sizable minority of the population abuse alcohol consumption.
It is estimated that 10-20% of males and… more
Abstract:DESCRIPTION (provided by applicant): Although most adverse outcomes due to asthma can be prevented through appropriate medical care and disease management, adolescents continue to be at high risk for negative consequences of uncontrolled asthma. Two contri
buting factors are 1) Failure of… more
Abstract:DESCRIPTION (provided by applicant): Drug abuse-associated behavior continues to be a significant factor in the spread of HIV/AIDS in the United States - both directly and indirectly. The use of injection and non-injection illicit drugs, as well as alcoho
l, can increase HIV transmission risk… more
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