Abstract:This proposal presents a technique for the precise determination of distance between nodes of a planar array of nanosatellites for synthetic aperture and sensor array applications. The proposed effort will result in a navigational technique that can precisely determine the positions of nanosatellite… more
Abstract:The ability to manufacture on the International Space Station will enable on-demand repair and production capability, as well as essential research for manufacturing on long-term missions.Having an Additive Manufacturing Facility (AMF) on the ISS will allow for immediate repair of essential… more
Abstract:Synchrotron-based science has had a great scientific impact and will continue to have great impact going forward. In spite of the large investment in the 3rd generation light sources, most beam lines do not preserve the sources phase profile or brightness all the way to the sample. For these high… more
Abstract:This Small Business Innovative Research SBIR Phase I project will use statistical analysis of historical medical records to create families of language models for each section of the traditional medical note and switch lexicons in and out of the automatic speech recognition (ASR) in real time based… more
Abstract:Herein, we propose a novel approach to achieving a broadband, phased-array transmitter operating at frequencies from 100-300 GHz. Our approach is based on the concept of optically distributing a pair of locked optical tones to an array of antenna coupled photomixers. Lightweight optical fibers… more
Abstract:An emerging class of passive millimeter-wave (pmmW) sensors currently provides an unmitigated threat to the US Navy. While considerable effort has been expended reducing RADAR signatures of the next generation of Naval vessels, these ship designs often present significant signatures to pmmW sensors.… more
Abstract:In this SBIR project, AlphaSense, Inc. and the Carnegie Mellon University propose to develop a RF receiver front end based on CMOS-MEMS components for miniaturized digital EVA radio applications. In Phase I, we have proven the feasibility of implementing a compact, low power and high performance S… more
Abstract:In this proposal, AlphaSense, Inc. and the University of Washington detail the development of a novel, high performance Ka band power amplifier for EVA radio applications. Key innovations of our approach include: a) The application of a class-E power amplifier to ensure high power efficiency, b)… more
Abstract:In this proposal, AlphaSense, Inc. (AI) and the University of Michigan (UM) detail the development of a novel automated and controlled dual laser ablation system for selective chrome removal. The key innovations of this proposal include the following: a) The combination of ns- and fs- laser ablation… more
Abstract:In this proposal, AlphaSense, Inc. details the development of a novel sensor for pitting corrosion monitoring and load distribution measurements. The key innovations of this proposal include the following: a) corrosion and load distribution measurements based on the electrical impedance measurements… more
Abstract:In the current SBIR program, AlphaSense aimed at developing a novel, handheld, non-destructive sensor to evaluate the integrity of Naval Advanced Amorphous Coatings (NAAC) in real time. In phase I, we have proven the feasibility of using the cavity perturbation technique to detect different types of… more
Abstract:DESCRIPTION (provided by applicant): Raman spectroscopy is a potentially important clinical tool for real-time diagnosis of diseases and in situ evaluation of living tissues. However, the application of Raman spectroscopy for tissue evaluation has been limited by the strong tissue fluorescence that… more
Abstract:DESCRIPTION (provided by applicant): Transition metal catalysts are widely used in the pharmaceutical industry for the production of active ingredients, precursors and new drug candidates. These products must be very pure, often requiring labor and energyintensive separation processes, to achieve… more
Abstract:DESCRIPTION (provided by applicant): The overall focus of this application is to develop nanofiltration membranes to recover the spent solvents generated from drug manufacturing processes allowing the solvents to be reused resulting in elimination of waste. This is also responsive to NIH RFP… more
Abstract:DESCRIPTION (provided by applicant): Novel Nanofiltration Membranes for Isolation of Pharmaceutical Compounds Project Summary: In the chemical manufacturing of pharmaceutical compounds, organic syntheses are often carried out in organic solvents and involve intermediates and final products with high… more
Abstract:DESCRIPTION (provided by applicant): The commercial syntheses of many pharmaceutical active ingredients and intermediates require acid catalysts and the removal of water to drive reactions to completion. Typical reactions include esterifications of carboxylic acids with alcohols, Friedel-Crafts… more
Abstract:DESCRIPTION (provided by applicant): Compact Membrane Systems (CMS) proposes to develop a perfluoro membrane reactor technology that will provide a generally applicable tool for removing water and oxygen from pharmaceutical synthesis processes. This innovation aims to improve product quality and… more
Abstract:Fossil fuels currently supply more than 85% of the worlds energy needs with the ensuing generation of 80% of all anthropogenic emissions of carbon dioxide. Carbon dioxide as a greenhouse gas is considered to be a major contributor to global warming. There is a concerted effort towards capturing… more
Abstract:Industrial hydrogen production relies primarily on natural gas and hydrocarbon feedstocks to drive the various reaction chemistries that lead to hydrogen generation. Carbon dioxide, the ultimate co-product when such feedstocks and processes are employed, necessarily becomes a major contaminant of… more
Abstract:Ethylene and propylene are major chemical industry raw materials and consume a great deal of energy related to their production. It is estimated that 230 trillion BTU/yr are consumed in olefin/paraffin separations. Significant energy consumption is employed when cryogenically separating ethane from… more
Abstract:Solvent extraction by hexane is the most common choice for extraction of oil/lipids from algae. However, hexane is not the best choice of solvent for algae oil extraction because of the need to market byproducts for human and animal consumption. Oil and hexane from the solvent extraction process are… more
Abstract:Vapors produced during the process of refueling cars are a significant source of Volatile Organic Compounds (VOCs) emissions. Uncontrolled emissions cause economic losses and pollute the environment. This problem is exacerbated when the gasoline contains bioethanol because its presence increases the… more
Abstract:Soybean is the major source for production of edible oils worldwide and in United States. Pressing of the soybean into flakes followed by the solvent extraction with hexane (solvent) is most widely practiced for extraction of oil. Separation of solvent from oil-solvent mixture for solvent recovery… more
Abstract:At the heart of scientific computing and numerical analysis are linear algebra solvers. In scientific computing, the focus is on the partial differential equations (PDEs) that arise from computational fluid dynamics (CFD), climate modeling, astrophysics, and structural and heat analysis that cannot… more
Abstract:In an attempt to build more computationally powerful systems and improve the FLOPS/dollar and FLOPS/Watt of high-performance computers (HPCs), we have recently seen the proliferation of GPU-based clusters. Many major vendors are now supporting this technology and such systems are becoming… more
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