Abstract:DESCRIPTION (provided by applicant): Transition metal catalysts are widely used in the pharmaceutical industry for the production of active ingredients, precursors and new drug candidates. These products must be very pure, often requiring labor and energyintensive separation processes, to achieve… more
Abstract:DESCRIPTION (provided by applicant): The overall focus of this application is to develop nanofiltration membranes to recover the spent solvents generated from drug manufacturing processes allowing the solvents to be reused resulting in elimination of waste. This is also responsive to NIH RFP… more
Abstract:DESCRIPTION (provided by applicant): Novel Nanofiltration Membranes for Isolation of Pharmaceutical Compounds Project Summary: In the chemical manufacturing of pharmaceutical compounds, organic syntheses are often carried out in organic solvents and involve intermediates and final products with high… more
Abstract:DESCRIPTION (provided by applicant): The commercial syntheses of many pharmaceutical active ingredients and intermediates require acid catalysts and the removal of water to drive reactions to completion. Typical reactions include esterifications of carboxylic acids with alcohols, Friedel-Crafts… more
Abstract:DESCRIPTION (provided by applicant): Compact Membrane Systems (CMS) proposes to develop a perfluoro membrane reactor technology that will provide a generally applicable tool for removing water and oxygen from pharmaceutical synthesis processes. This innovation aims to improve product quality and… more
Abstract:Fossil fuels currently supply more than 85% of the worlds energy needs with the ensuing generation of 80% of all anthropogenic emissions of carbon dioxide. Carbon dioxide as a greenhouse gas is considered to be a major contributor to global warming. There is a concerted effort towards capturing… more
Abstract:Industrial hydrogen production relies primarily on natural gas and hydrocarbon feedstocks to drive the various reaction chemistries that lead to hydrogen generation. Carbon dioxide, the ultimate co-product when such feedstocks and processes are employed, necessarily becomes a major contaminant of… more
Abstract:Ethylene and propylene are major chemical industry raw materials and consume a great deal of energy related to their production. It is estimated that 230 trillion BTU/yr are consumed in olefin/paraffin separations. Significant energy consumption is employed when cryogenically separating ethane from… more
Abstract:Solvent extraction by hexane is the most common choice for extraction of oil/lipids from algae. However, hexane is not the best choice of solvent for algae oil extraction because of the need to market byproducts for human and animal consumption. Oil and hexane from the solvent extraction process are… more
Abstract:Vapors produced during the process of refueling cars are a significant source of Volatile Organic Compounds (VOCs) emissions. Uncontrolled emissions cause economic losses and pollute the environment. This problem is exacerbated when the gasoline contains bioethanol because its presence increases the… more
Abstract:Soybean is the major source for production of edible oils worldwide and in United States. Pressing of the soybean into flakes followed by the solvent extraction with hexane (solvent) is most widely practiced for extraction of oil. Separation of solvent from oil-solvent mixture for solvent recovery… more
Abstract:A novel high performance, lightweight vehicle armor system for the Expeditionary Fighting Vehicle (EFV) is proposed. Following past work with perforated metals for weight efficient armor, the present work examines ceramic-based armor systems where the ceramic component has a novel design (e.g.,… more
Abstract:The Army is in need of an improved material for use in bridge structures. Key requirements are reduced weight relative to current metallic structures (steel and aluminum), high strength, resistance to catastrophic failure, attractive cost, and resistance to environmental factors (weather, corrosion… more
Abstract:To meet the ever-increasing challenges imposed by next generation weapon systems and continued reduced manning efforts, Quantum Leap Innovations, Inc. will collaborate with the Institute for Simulation and Training (IST) at the University of Central Florida (UCF) to develop adaptive, embeddable, and… more
Abstract:Existing Anti-Submarine Warfare (ASW) mission planners can specify patrol regions for available sensor platforms and provide detailed, coordinated search tracks for each platform. However, most of the planners have not considered any real-time sensor information feedback during optimization and… more
Abstract:The proposed SBIR Phase I program is to establish a ferromagnetic resonance (FMR) measurement setup that is capable of characterizing the FMR spectrum with high sensitivity and over a broad frequency, as well as nonlinear behaviors at high microwave power. The proposed effort also includes modeling… more
Abstract:DESCRIPTION (provided by applicant): Analysis of glycoprotein polypeptide sites of carbohydrate attachment and the structures of the glycans present on these proteins requires the combination of high resolution chromatographic separations and sophisticatedmass spectrometry. Hydrophilic interaction… more
Abstract:DESCRIPTION (provided by applicant): Life sciences research and other critical bioanalytical applications would strongly benefit from faster and higher resolution liquid chromatographic (HPLC) separations for both small molecules and larger molecules suchas proteins, peptides, glycopeptides, and… more
Abstract:Single chirality of single-walled carbon nanotubes (SWCNTs) is critical for their superb mechanical, thermal, optical and electronic properties. All known methods for producing nanotubes give mixtures of tubes with different chiralities. Physical separation of SWCNT by chirality is thus an enabling… more
Abstract:Hyperspectral imaging systems acquire the spatial and spectral information of the image scene simultaneously, and thus find important applications in remote sensing, military surveillance, and target identification. Most contemporary hyperspectral imaging systems operate at UV/VIS/NIR (ultra… more
Abstract:The global war on terror has dramatically changed the environment in which today's warfighter operates. Many of the locations in theater require moving troops and equipment into areas with unimproved landing zones. Loss of situational awareness in degraded visual environments is one of the largest… more
Abstract:We propose to use the open source rendering program Blender in combination with MATLAB to create a millimeter wave scene simulation program that will be specifically aimed at simulating ships in a nautical environment. We already possess relevant data from experiments performed at both Dahlgren and… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will research and develop a software system to model the complex and varied rights structures used in private company finance. This system will show the behavior (such as the economic payouts to each stakeholder) of capital structures… more
Abstract:Sponsored by NAVAIR, Accudyne Systems completed a Phase 1 SBIR program, developing an equipment and process concept for cost-effective fabrication of composite rotary wing main rotor blade spars. The CH-53K spar was the study focus. The recommended work cell concept combines automated tape placement… more
Abstract:In this proposal, AlphaSense, Inc. (AI) and the Carnegie Mellon University (CMU) detail the development of RF front end based on MEMS components for miniaturized digital EVA radio. Key innovations of our approach include: a) the use of a novel parallel receiver front end architecture based on MEMS… more
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