Abstract:The accurate identification of seafood species and origin has become an extremely important topic in the food industry. Mislabeling a lower valued seafood product to represent a species of higher value constitute economic fraud. In addition, this mislabeling compromises proper geographic origin… more
Abstract:Sturgeons have very high potential to become an important and profitable aquaculture species in the US, as males are grown for meat and brood stock and female sturgeon are primarily raised for their eggs (caviar). In fact, sturgeon caviar is the highest-valued aquaculture product worldwide, selling… more
Abstract:The broader impacts/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is that it will enable a dramatic leap in the technology of electrooptic modulators. Electrooptic modulators have widespread applications in fiber-optic telecommunications. The modulators are… more
Abstract:DESCRIPTION (provided by applicant): Acute pesticide poisoning remains a vast health problem in the developed and developing world. Domestically, a 2004 study estimates that 18 of every 100,000 US agricultural workers suffer from acute pesticide poisoning.On top of that, long time effects have also… more
Abstract:MTI-101 is a cyclic beta-hairpin peptide that binds CD44 with high affinity and kills multiple myeloma cell lines in vitro and blocks the growth of myeloma tumors in 2 different murine models. This interaction of MTI-101 with the surface of MM cells causesprogrammed cell necrosis, whereas all… more
Abstract:This Small Business Technology Transfer Research (STTR) Phase I project initiates development of a conceptually new ?seamless? micro air vehicle (MAV) design based on distributed array of synthetic-jet micro-actuators (SJMAs) operating in a closed-loop flight control system to achieve unprecedented… more
Abstract:DESCRIPTION (provided by applicant): Smoking remains the number one avoidable cause of death in the United States. Current therapies including nicotine replacement, inhibition of the dopamine system with bupropion, and partial activation of the 4 2 neuronal nicotinic acetylcholine receptor (nAChR)… more
Abstract:DESCRIPTION (provided by applicant): According to the American Cancer Society, half of all men and one-third of all women in the United States will develop cancer in their lifetime. While chemotherapy has dramatically improved the survival rate of cancer patients, it comes at the cost of severe… more
Abstract:This project aims to optimize the lead formulation of epothilone D encapsulated in a stable nanoparticle for the treatment of solid malignancies, and assist in providing for the GMP manufacturing and GLP toxicology studies required for IND submission and translation into human clinical trials. The… more
Abstract:The government has identified the need for scientific measurements of the stimuli produced on a human surrogate for human effects testing of different non-lethal weapon technologies including blunt trauma, monochromatic and broadband light, blast over-pressure thermal energy, electrical current,… more
Abstract:The objective of this Phase I proposal is to demonstrate the feasibility of using a combination of chemical and nanoparticle additives to produce high-performance, temperature-insensitive composite solid propellants with plateau burning rates greater than 1 in/s at 2000 psi for use in Navy aircraft… more
Abstract:During the course of the proposed work Helicon will develop and demonstrate Solid Fuel Ramjet (SFRJ) high performance fuels based on proprietary in-situ grown aluminum nanoparticles. Currently available solid fuel grains do not yet meet the Navy"s mission requirements for ramjet application.… more
Abstract:The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to help researchers to identify novel scientific hypotheses and make discoveries by harnessing the power of big data being generated in biological and biomedical fields. It is well known that… more
Abstract:We propose to develop a terrain database generation and editing tool for the Navy. This tool will have a simple interface designed for use by persons with no prior terrain tool experience. The tool will ingest standard and non-standard source data (elevation, imagery, and terrain features) and… more
Abstract:e-Tect has created a medication adherence monitoring system called ID-Cap consisting of a tag smaller than the size of a postage stamp that can be wrapped around a capsule or attached to a pill. When the tagged medication is ingested, it activates and sends a signal to a reader worn on the arm. The… more
Abstract:DESCRIPTION (provided by applicant): Poor medication adherence has a significant negative impact on patients, clinical study outcomes, and the healthcare system in general. As much as 25% of all healthcare costs could be avoided if patients reliably took their prescribed medications. Medication… more
Abstract:Decisions made at concept design have profound impacts on total life cycle cost. The industry trend is to apply automated software tools during concept design so larger numbers of alternatives can be evaluated and optimal, feasible solutions identified. Current ship concept design software tools… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project aims to further enhance the efficiency and lifetime of quantum dot light emitting diodes (QD-LEDs) used for displays. An active matrix QD-LED prototype display will be demonstrated using solution processing. The lifetime of QD-LED will… more
Abstract:DESCRIPTION (provided by applicant): In the U.S., prostate cancer is the second leading cause of cancer death in men, and one in six men will eventually develop prostate cancer during his lifetime. Currently, the prostate specific antigen test and digitalrectal examination are the most predominant… more
Abstract:GameSim is proposing to rapidly design and develop an extensible correlation assessment framework by reusing underlying technologies in Conform, an existing commercial off-the-shelf source data visualization and analysis tool developed by GameSim. GameSim will undertake a detailed research effort to… more
Abstract:Unmanned Aerial System (UAS) operation represents a stressful, cognitively challenging domain where operators are routinely subjected to both occupational and combat stressors and performance failures can have catastrophic effects. Effective performance in such conditions has many dimensions,… more
Abstract:The broader impact/commercial potential of this project is in enabling a novel and powerful diagnostic technique that could open the door to emergence of a new class of micro-scale ultrasonic characterization devices. The immediate impact of the project is in the field of biomedical sensors and aims… more
Abstract:This Small Business Innovation Research Phase I project will explore the feasibility of fabricating and optimizing a thermoelectric (TE) device suitable for integration into a photovoltaic (PV) cell to increase the performance and lifetime of the PV cell. The TE device can be used to cool and heat… more
Abstract:The development & commercialization of an innovative, simple-to-use, durable & cost-effective system capable of delivering fluoride to small & med-size potable water systems is essential to increase the availability of fluoridated water to 80 percent of the nation's population by 2020 (CDC's Health… more
Abstract:This project is is applying the semantic web to the data produced by chemical-physics simulations. The semantic web allows data to be placed on a web site in a way that computers can understand it. This will allow a computer to browse a giant global graph of data, as an agent for scientists, and… more
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