Abstract:DESCRIPTION (provided by applicant): O-glycosylation of nuclear and cytoplasmic proteins by a single ?-N-acetyl-D-glucosamine moiety (O-GlcNAc) is a common post-translational modification that is highly dynamic and fluctuates in response to cellular stimuli. This type of glycosylation has been… more
Abstract:In Phase II, we will partner with CCI to deploy our fMRI protocol in 50 of their dogs entering advanced training, and determine neural biomarkers that predict successful completion of the course and placement with a human. Because MRI is expensive and lab
Abstract:This Small Business Innovation Research Phase I project seeks to develop a force sensitive touch surface technology that will overcome the technical shortcomings of currently available technologies. The design leverages the thin form factor, optical transmissivity, and cost advantages of organic… more
Abstract:This Small Business Innovation Research Phase II project seeks to commercialize a force sensitive solution for touch applications that will overcome the technical shortcomings of currently available technologies. The design utilizes the sensitivity, size, and cost advantages of… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project uses enhanced MIMO (multiple-input, multiple-output) technology to boost capacity, coverage, and enhance link robustness in wireless communications without using additional spectrum. This is accomplished by transmitting independent data… more
Abstract:There is unmet need for rapid, cost effective in vitro methods to identify chemicals that pose a hazard to the human brain. A number of in vitro assays utilizing primary cells have been tested in an effort to devise effective models to prioritize chemicals for further in depth toxicity studies.… more
Abstract:ABSTRACT: Corrdesa is validating a finite element analysis method of predicting galvanic corrosion locations and relative severity between dissimilar metals using commercially available GalvanicMaster software. This project will demonstrate that this same approach can be modified and extended to… more
Abstract:IK9, LLC, and Auburn University shall collaborate in the development of prototype procedures for conducting cognitive neuroscience studies employing fMRI imaging of the brains of unrestrained dogs while they are in an awake and responsive state. IK9 is an international leader in innovative working… more
Abstract:DESCRIPTION (provided by applicant): This Fast-Track SBIR application submitted by SimpleC of Atlanta, Georgia, requests funds to test our current behavior management technology for persons with dementia (PWD), the SimpleC Companion, and to develop and test a new mobile tablet, the SimpleC Wellness… more
Abstract:The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is a novel high strength, surface porous layer that can improve integration of non-metal orthopedic implants, resulting in better clinical outcomes. This improvement to orthopedic implants is… more
Abstract:DESCRIPTION (provided by applicant): Improving Articulatory Precision in Neurologically Compromised Adults Using Audiovisual Biofeedback. One of the most frustrating impairments of neurological damage is the inability to communicate properly via the speechmodality due to weakness in the oral motor… more
Abstract:This SBIR Phase II project will result in a system that can scan building interiors and exteriors and construct corresponding detailed, photo-realistic 3D models. Having such models is useful in a number of applications. However, the existing approaches for the construction of such models are labor… more
Abstract:DESCRIPTION (provided by applicant): Sinoora Inc. proposes to develop an on-chip spectral domain-optical coherence tomography (SD-OCT) system for ophthalmic applications. Phase I will concentrate on demonstrating the passive optical components of the OCT system on a single chip. The passive… more
Abstract:Hadoop style systems have done an excellent job of providing scalable long term disk bound data storage and enjoy wide acceptance in both Government and the private sector. However, Hadoop implementations suffer from performance limitations with respect
Abstract:Clostridium difficile infection (CDI) is a common nosocomial pathogen that plagues patients because of it relatively high rate of recurrence. Although diagnosis for primary CDI is very sensitive, there are not tests to predict recurrence. Recent human clinical trials show monocolonal antibodies to… more
Abstract:DESCRIPTION (provided by applicant): Prostate cancer (PCa) is the most diagnosed cancer among men in developed countries including the United States with significant medical cost burdens. Tremendous advances have been made in PCa screening technologies, which allow early detection and treatment.… more
Abstract:DESCRIPTION (provided by applicant): The mission of Novab is to utilize the unique properties of lamprey generated Variable Lymphocyte Receptors (VLRs) to develop effective, complementary and/or superior therapeutics to those currently derived from mammalian monoclonal antibodies (mMAbs). In the… more
Abstract:DESCRIPTION (provided by applicant): KDH Research and Communication (KDHRC) proposes to develop and evaluate Dientes Fuertes, Vida Sana (DFVS), a culturally-competent program to prevent primary tooth decay in low-income Latino children ages zero to six. Toeffectively reach low-income Latino children… more
Abstract:? DESCRIPTION (provided by applicant): A policy statement by the World Health Organization notes that, the male latex condom is the single, most efficient, available technology to reduce the transmission of HIV and other sexually transmitted infections. Unfortunately, despite decades of condom… more
Abstract:The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project includes improving the transportation planning process through better and more frequent data. An integral part of transportation planning at the federal, state, regional, and local levels of… more
Abstract:DESCRIPTION (provided by applicant): Pharmaceutical proteins comprise a large and rapidly growing segment of the pharmaceutical market. To be safe and effective, pharmaceutical proteins must possess not only the correct covalent structure, but also the correct non-covalent three-dimensional folded… more
Abstract:This SBIR Phase II project will complete the research and development required to produce a Skills- and Assessments-based Learning Environment for high school biology classes. This project will create a modular software system that is underpinned by a unique data analysis platform. Using 3D… more
Abstract:ABSTRACT: Generation Orbit is proposing to develop a system architecture rooted in the success of the HIFiRE program, but capable of longer duration testing at high dynamic pressure, high Mach number flight conditions, flexible enough to maximize accessibility to customer defined test windows,… more
Abstract:The Holomorphic Embedding Load Flow Method (HELM) is a breakthrough that brings significant advances to the field of power systems. It provides a non-iterative procedure to compute, with mathematically proven guarantees even near voltage collapse, the correct operative power flow solution, to the… more
Abstract:Terminal Velocity Aerospace, LLC (TVA) proposes to improve utilization of the International Space Station (ISS) by providing a system for on-demand return of experiment samples to Earth. TVA is presently developing a small reentry device (RED) capable of returning small payloads from space, with… more
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