Abstract:DESCRIPTION: Glycans have several distinct properties that make them excellent targets for disease biomarkers. Firstly, the location of the glycans on the cell surface makes them the first point of contact of cellular interactions and thus crucial in thecontrol of normal metabolic processes. Cell… more
Abstract:DESCRIPTION (provided by applicant): Inhibikase Therapeutics is a clinical stage, biopharmaceutical company that has developed a host- targeted mechanism of action to treat AIDS-related and drug-induced progressive multifocal leukoencephalopathy (PML). PMLis a demyelinating disease of the central… more
Abstract:This Small Business Technology Transfer (STTR) Phase I project will prove the technical and commercial feasibility of a single-use polymer microarray for electromechanical transfection of biological cells. Alternative gene transfer solutions are needed to access the potential held in… more
Abstract:Many military and commercial applications have turned to power electronics to run a variety of systems efficiently, quietly, cheaply, and precisely. Therefore, there is an urgent need for efficient energy storage systems with both high energy and power densities. Supercapacitors have gained… more
Abstract:DESCRIPTION (provided by applicant): This Phase II SBIR proposal aims at the continued development and commercialization of a new class of high-performance X-ray imaging screens based on the recently developed core/shell nanorod (NR) and nano-tetrapods (NTs) structures. These multi-dimensional… more
Abstract:ABSTRACT: A Propellant Health Monitoring (PHM) Sensor for Solid Rocket Motors (SRMs) utilizes actual propellant components in a tiny new sensor called AgeAlert. These sensors provide real-time data corresponding to mechanical property degradation resulting from environmental aging of propellants. … more
Abstract:Polymer Aging Concepts, Inc. proposes to develop a"Smart Shelf Life"(SSL) tag which provides a low cost health monitoring system for ordnance based on a new condition monitoring sensor technology called AgeAlert. The AgeAlert sensor in SSL labels comprises a conductive composite element… more
Abstract:In Phase II, Propagation Research Associates, Inc., (PRA) proposes to complete the development of a real-time nowcast of ionospheric scintillation impacts on GPS users. Continuing its partnership with NASA’s Jet Propulsion Laboratory, PRA will implement real-time production of a map of ionospheric… more
Abstract:ABSTRACT: Propagation Research Associates, Inc., (PRA), teamed with the Jet Propulsion Laboratory (JPL), proposes to design and evaluate an algorithm to produce useful measurements of the state of the ionosphere from Global Positioning System (GPS) equipment used on mobile platforms. We will… more
Abstract:PRA is proposing an innovative Orthogonal Space Projection (OSP) processing technology and a parallel processing architecture to adaptively cancel discrete clutter in real-time. The OSP technique utilizes adaptive waveform diversity with a suite of waveforms with low correlation time-sidelobes. In… more
Abstract:The increase in unmanned systems, also known as UxVs, on the battlefield creates the need for coordinated activity among multiple UxVs that work effectively in collaboration with the Warfighters who must be able to rapidly and easily command their operations, insure their compliance with intent in a… more
Abstract:Traditional selection and training practices are essential initial selection tools that show some general levels of predictive validity overall. However, current Navy selection tools are not good predictors of performance for Navy air system AVOs. In our targeted solution, we utilize proprietary… more
Abstract:Navy command and control (C2) personnel must make decisions about events and activity they are not able to directly perceive. They must interpret information represented on an interface or over a communication device into a mental picture of the relevant environment - a mental model of the current… more
Abstract:This Small Business Innovation Research Program Phase II project proposes to develop a simple, single-shot, inexpensive, and complete laser-pulse measurement device for ~100-picosecond to ~10-nanosecond pulses. Long (>10 nanosecond) pulses are easily measured, and recently developed techniques… more
Abstract:DESCRIPTION (provided by applicant): The proposed project, titled Reduce the Risk: An Affect Management Program for HIV Prevention, will examine the use of immersive virtual reality technology as an intervention tool for HIV Prevention with adolescents. Adolescents are at risk for contracting HIV.… more
Abstract:DESCRIPTION (provided by applicant): Pediatric Food Allergy (FA) is recognized as a serious public health concern that affects approximately 4-8% of children, with symptoms affecting multiple organ systems, including skin, the respiratory tract, and the GItract. Food-induced anaphylaxis, which is a… more
Abstract:DESCRIPTION (provided by applicant): Insufficient sleep in children is recognized by Congress and the Department of Health and Human Services as a high priority target for clinical scientific investigation given its consist link with enduring physical, emotional and behavioral problems, including… more
Abstract:DESCRIPTION (provided by applicant): Adolescents in mental health treatment are at greater risk for HIV and other STIs than their peers due to an earlier age of onset of sex, less protected sex, more sexual partners, and more frequent substance use. This greater risk is due to multiple factors… more
Abstract:Phased arrays are a key component in modern naval warfare. Its applications range from radars to electronic warfare (EW), surveillance & communications, etc. Its important applications to other military and commercial systems and platforms are obvious. For decades, wideband wide-scan planar… more
Abstract:Compared to Lithium-Ion (Li-ion) batteries, which have earned the largest share of the battery storage market, flywheel energy storage systems (FESS) offer significant advantages in cycle life, power density and turnaround efficiency for short charge/discharge times, but normally at a higher cost.… more
Abstract:Conventional Li ion batteries have a number of limitations that prevents them from becoming the energy storage media for electric (EV) and hybrid electric vehicles (HEV). Many of these limitations could be ultimately traced to properties and limitations of the liquid organic electrolytes used in the… more
Abstract:This Small Business Innovation Research Phase I project aims to create a unique maskless lithography technology called "Exposure Controlled Projection Lithography" (ECPL), to enable manufacturing of gradient index (GRIN) optical components with controlled physical aspheric shapes. ECPL is… more
Abstract:The innovation in this project comes from the novel call audio analysis techniques that can be used to create a fingerprint of the source of a telephone call. Such fingerprints can reveal valuable information about the call source, including the type of the calling device (landline, Voice-over IP or… more
Abstract:DESCRIPTION (provided by applicant): This project will develop a suite of innovative learning experiences that will engage high school students in neuroscience and thereby increase their interest in possible careers in this area. This will be achieved by creating highly interactive and immersive… more
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