Abstract:ABSTRACT: ABSTRACT F3 Solutions (F3) is a woman owned small business with key personnel, with over a combined 50 years of experience specific to Air Force Environmental Engineering, and has experience providing research and development support to satisfy the overall objectives for blast booth… more
Abstract:DESCRIPTION (provided by applicant): Haplotype is fundamental genetic information; it provides essential information for deciphering the functional and etiological roles of genetic variants. Current sequencing and genotyping technologies deliver only halfof the genetic information of each individual… more
Abstract:Recent advances in mammalian artificial chromosome design and engineering offer an alternative to existing methodologies for cellular bioengineering and address unmet needs to bioengineer more complex functionalities into human cells for subsequent commer
Abstract:DESCRIPTION (provided by applicant): The major barriers limiting the application of MRI to detect small liver lesions and metastasis at the early stage and patient selection for targeted therapy based on molecular imaging of disease biomarkers, are due tothe lack of desired MRI contrast agents… more
Abstract:This proposal addresses the challenge of providing weather and climate information to support the operation, management and planning for wind-energy systems. There is a growing need for extended range forecast information as wind power increases its penetration into the grid. Future scenarios on… more
Abstract:Technology focusing on collection, processing, and analysis of real-time data is playing a major role in military and civilian applications. With the advent of GPU and accelerator computing, the collection, processing, and analysis of real-time data streams is technically possible at an… more
Abstract:DESCRIPTION (provided by applicant): Obesity is considered the number one health problem in the US and Europe, affecting 10% to 30% of adult populations. Obese individuals are more likely to acquire a variety of secondary diseases including diabetes, heartproblems, immune deficiencies, some types of… more
Abstract:To meet the challenge of aiding the Army aviator with flying a complex aircraft in a dangerous region of airspace, Applied System Intelligence, Inc. (ASI), with participation from Sikorsky Aircraft Company (SAC), plans to add decision-aiding behaviors to the UH-60M Black Hawk helicopter in a system… more
Abstract:The objective for this SBIR is to develop a PMESII-PT workbench i.e., a tool that will enable Civil Affairs staff to gather, organize, and maintain knowledge relevant to stability operations. Two factors limit the military"s ability to manage stability operations. First, there simply are… more
Abstract:ASI proposes to develop and evaluate a Phase I Demonstration System for the Improved Fusion Algorithm System (IFAS) based on its artificial intelligence technology for building Associate Systems. This Demonstration System will be based on requirements analysis with a written requirements document… more
Abstract:The objective for this effort is to design and develop a common software foundation for the Army to use in a variety of deployment environments including mobile / handheld devices, mounted units and command posts. The work to be done involves both the development of a software architecture and the… more
Abstract:DESCRIPTION (provided by applicant): In response to the program announcement for Phase IIb proposals for complex, in-vitro brain and behavior tools (PA-11-135), this proposed study automates all aspects of in-vitro Microelectrode Array (MEA) technology todeliver the first ever high throughput… more
Abstract:DESCRIPTION (provided by applicant): The manufacturing of recombinant coagulation factor VIII is a complex, labor and capital intensive endeavor. Of the recombinant proteins currently marketed, coagulation factor VIII is manufactured with the lowest efficiency and is by far the most expensive on a… more
Abstract:ABSTRACT: The Area-I team propose to leverage their expertise to develop an extended-endurance Air-Launched, Tube-Integrated Unmanned System (ALTIUS). ALTIUS, meaning"higher"in Latin, will provide a paradigm shift in the performance of small, tube-launched remotely piloted aircraft (RPA).… more
Abstract:The Area-I team has developed and flight tested the unmanned Prototype-Technology Evaluation and Research Aircraft or PTERA ("ptera" being Greek for wing, or wing-like). The PTERA flew successfully during Phase I of this program, and stands to enhance the already capable NASA Aeronautics… more
Abstract:The main goal of this work is to design, implement, and demonstrate a guidance and mission planning toolbox for air-launched, unmanned systems, such as guided dropsondes, sonobuoys, or surveillance aircraft, with the primary goal of enabling users to more effectively achieve mission goals by… more
Abstract:Area-I, Incorporated personnel have led the design, fabrication, and flight testing of twelve unmanned aircraft and one manned aircraft. Partnered with NASA and Boeing, Area-I has developed the unmanned Prototype-Technology Evaluator and Research Aircraft or PTERA ("ptera" being Greek for… more
Abstract:ABSTRACT: Area-I proposes to develop an Integrated Multi-mode Propulsion system for UAS Leveraging Speed and Endurance (IMPULSE) to provide a paradigm shift in the performance of small unmanned aircraft systems (SUAS). The development of IMPULSE will lead to a state-of-the-art, high-energy-density… more
Abstract:The next generation of technology for laser weapons, i.e. diode pumped or fiber, requires significant electrical power for driving the laser and supporting systems. There is a need for compact and lightweight power generation, storage, and conditioning for transitioning the laser technology to an… more
Abstract:Global Technology Connection, Inc. in conjunction with its partner, Vanderbilt University, is proposing to build a Fusion-enhanced Vehicle Diagnostics System (FVDS) framework to combine various information to help make go/no-go decisions from a safety point of view. Specifically single vehicle will… more
Abstract:Global Technology Connection, Inc. (GTC) seeks to develop generic time and frequency domain analysis modeling and analysis tools to analyze and determine mitigation strategies to maintain power quality with high dynamic aircraft power systems operating with electrical accumulator units (EAU). Phase… more
Abstract:DESCRIPTION: Glycans have several distinct properties that make them excellent targets for disease biomarkers. Firstly, the location of the glycans on the cell surface makes them the first point of contact of cellular interactions and thus crucial in thecontrol of normal metabolic processes. Cell… more
Abstract:DESCRIPTION (provided by applicant): Inhibikase Therapeutics is a clinical stage, biopharmaceutical company that has developed a host- targeted mechanism of action to treat AIDS-related and drug-induced progressive multifocal leukoencephalopathy (PML). PMLis a demyelinating disease of the central… more
Abstract:Many military and commercial applications have turned to power electronics to run a variety of systems efficiently, quietly, cheaply, and precisely. Therefore, there is an urgent need for efficient energy storage systems with both high energy and power densities. Supercapacitors have gained… more
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