An Official Website of the United States Government
Search
Narrow Search Filters:
State:Hawaii
Company: HAWAII BIOTECH, INC. Agency/Program/Year/Phase: DOD / SBIR / 1994 / 1
Abstract: Several fundamental parameters need to be addressed with regard to the development of biosensors. Protein stability is a major criteria for sensors devoted to long-term monitoring. The enzyme label is typically the most unstable componenet in biosensors. Additional problems encountered with… more
Company: HAWAII BIOTECH, INC. Agency/Program/Year/Phase: DOD / SBIR / 1994 / 1
Abstract: The filamentous fungi, owing to their ability to secrete high levels of proteins, are attractive organisms for the expression and secretion of heterologous proteins of commercial and medical value. Secretion is a key element in their attraction, for secretion enables proper folding and processing of… more
Company: Synthetic Technology Agency/Program/Year/Phase: HHS / SBIR / 1994 / 1
Abstract: Natural testosterone and numerous synthetic analogs are known to stimulate biosynthesis ofproteins and are used as therapeutic agents. Most of them are DEA controlled substances. Improper usemay cause health risks. Steroid abuse is a widespread problem. There is a practical need to screen forabused… more
Company: TECHNICAL RESEARCH ASSOC., INC. Agency/Program/Year/Phase: DOD / SBIR / 1994 / 2
Abstract: High rate-of-fire weapons are subject to significant barrel erosion as projectile velocity and burst lengths are increased. Bore temperatures exceeding the melting point of steel can be easily reached because of the low thermal conductivity of the steel barrel. Barrels comprised of copper/graphite… more
Company: TECHNICAL RESEARCH ASSOC., INC. Agency/Program/Year/Phase: DOD / SBIR / 1994 / 2
Abstract: High-power ammonia arcjet thrusters are being investigated as primary propulsion systems for carrying satellites into high altitude orbits. As a method to enhance the power levels and efficiency of the engine, the thermal emissivity of the outer anode surface must be substantially enhanced. Ideally,… more
Company: TECHNICAL RESEARCH ASSOC., INC. Agency/Program/Year/Phase: DOD / SBIR / 1994 / 2
Abstract: In the next generation of air-breathing high-performance engines, significant engine performance improvements are envisioned by combusting hydrogen with air in a regeneratively cooled carbon/carbon composite combustion chamber. Surfaces subjected to aerodynamic heating will also be cooled by… more
Company: TECHNICAL RESEARCH ASSOC., INC. Agency/Program/Year/Phase: DOD / SBIR / 1994 / 1
Abstract: N/A
Company: HAWAII BIOTECH, INC. Agency/Program/Year/Phase: HHS / SBIR / 1993 / 2
Abstract: THIS PHASE I PROJECT IS DESIGNED TO TEST THE FEASIBILITY OF PURIFYING TAXOL BY IMMUNOAFFINITY CHROMATOGRAPHY. THE USE OF THIS TECHNIQUE FOR PURIFICATION OF A LOW MOLECULAR WEIGHT COMPOUND WITH LOW AQUEOUS SOLUBILITY HAS NOT BEEN REPORTED TO DATE. TAXOL-SPECIFIC MONOCLONAL ANTIBODIES WILL BE SELECTED… more
Company: HAWAII BIOTECH, INC. Agency/Program/Year/Phase: HHS / SBIR / 1993 / 1
Abstract: A Taxol prodrug derivative will be prepared. This compound will be tested for its differential cytotoxicity compared to Taxol and for its ability to be enzymatically activated. The cytotoxicity of the prodrug in combination with a monoclonal-antibody enzyme conjugate in the presence of targeted and… more
Company: HAWAII BIOTECH, INC. Agency/Program/Year/Phase: NSF / SBIR / 1993 / 1
Abstract: THE DEVELOPMENT OF MICROBIAL SYSTEMS FOR EXPRESSION OF HETEROLOGOUS PROTEINS HAS ENABLED THE ISOLATION OF GREATER AMOUNTS OF SOURCE PROTEINS, OFTEN IN GREATER PURITY THAN IS POSIBLE FROM THE ORIGINAL SOURCE. PROTEINS SO EXPRESSED HAVE APPLICATIONS RANGING FROM INDUSTRIAL USE, THROUGH PROTEIN… more
Company: HAWAII BIOTECH, INC. Agency/Program/Year/Phase: HHS / SBIR / 1993 / 1
Abstract: Regulation of gene expression is critical for cellular and organismal development, and it often plays an important role in expression of heterologous recombinant proteins. Toward development of regulated expression vectors for filamentous fungi that will minimize materials cost and manipulation of… more
Company: HAWAII BIOTECH, INC. Agency/Program/Year/Phase: HHS / SBIR / 1993 / 1
Abstract: The filamentous fungi, owing to their ability to secrete high levels of proteins, are attractive organisms for the expression and secretion of heterologous proteins of commercial and medical value. Secretion is a key element in their attraction; secretion provides the opportunity for complex… more
Company: Hawaii Fish Company Agency/Program/Year/Phase: USDA / SBIR / 1993 / 1
Abstract: THE STRIPED SNAKEHEAD CHANNA STRIATUS IS A HIGHLY ESTEEMED FOODFISH IN SOUTHEAST AND SOUTH ASIA. MILLIONS OF FISH ARE CONSUMED ANNUALLY IN COUNTRIES OF THIS REGION. SEVERAL THOUSAND METRIC TONS OF FROZEN WHOLE SNAKEHEAD ARE ALSO IMPORTED ANNUALLY INTO NORTH AMERICA FOR SALE IN DOMESTIC ASIAN SEAFOOD… more
Company: Kona Cinder & Soil Agency/Program/Year/Phase: USDA / SBIR / 1993 / 1
Abstract: KONA CINDER & SPOILS, INC. IS A SMALL-BUSINESS INVOLVED IN THE AGRICULTURAL/LANDSCAPE SOIL BUSINESS IN KONA, WEST HAWAII (ON THE ISLAND OF HAWAII, 30 MINUTES BY AIR FROM HONOLULU). THE ISLAND OF HAWAII SUPPORTS AN AGRICULTURAL-BASED ECONOMY, RANKING FIRST IN MACADAMIA NUT AND COFFEE PRODUCTION IN… more
Company: Royal Hawaiian Sea Farms Inc. Agency/Program/Year/Phase: USDA / SBIR / 1993 / 2
Abstract: THIS PROJECT IS TO DETERMINE IF CREATIVE AQUACULTURE TECHNIQUES CAN BE APPLIED TO CULTIVATE SEA CUCUMBERS ON A COMMERCIAL SCALE. THREE MAJOR EXPERIMENTS WILL TEST THE NEWTECHNIQUES DESIGNED FOR COMMERCIAL APPLICATION. THE OBJECTIVES ARE: 1) TO INCREASE REPRODUCTIVE EFFICIENCY AND DEVELOP ASSOCIATED… more
Company: Royal Hawaiian Sea Farms Inc. Agency/Program/Year/Phase: USDA / SBIR / 1993 / 1
Abstract: N/A
Company: TECHNICAL RESEARCH ASSOC., INC. Agency/Program/Year/Phase: DOD / SBIR / 1993 / 2
Abstract: THE OVERALL OBJECTIVE OF THIS PROJECT IS TO INTEGRATE TERFENOL-D INTO NEW ACTUATOR DESIGNS APPLICABLE TO DEXTEROUS EXOSKELETAL FEEDBACK SYSTEMS FOR TELEROBOTIC APPLICATIONS. THE DEVELOPMENT OF NEW EFFICIENT, RESPONSIVE, SMALL, LIGHTWEIGHT ACTUATORS IS CRITICAL TO THE ACHIEVEMENT OF SENSORY FEEDBACK… more
Company: TECHNICAL RESEARCH ASSOC., INC. Agency/Program/Year/Phase: DOD / SBIR / 1993 / 2
Abstract: THERMOSET RESIN IMPREGNATED YARNS, FABRICS AND TAPES (PREPREGS) COMPRISE A SIGNIFICANT FRACTION OF THE MATERIALS USED IN THE FABRICATION OF CURRENT AND DEVELOPING AIR FORCE AIRCRAFT SYSTEMS. TWO PROBLEMS EXIST, HOWEVER, WITH THE PREPREG MATERIALS. THESE MATERIALS HAVE ONLY A SIX-MONTH SHELF LIFE AND… more
HELP FOR NARROW YOUR SEARCH
Search Options
Search for Either Criteria
Narrowing the Search Results
Search Options
There are several categories such as “By Agency”, “By Year”, “By State” etc. Select a checkbox within a category to refine your search results.
Each of your selections is listed in the “Narrow Search Filters” bar. You can uncheck these selections to remove them.
Search for Either Criteria
When you select multiple values within a category, the results will include values that match either of the selections. For example, selecting “2005” and “2007” in the “By Year” category will display results that include either 2005 OR 2007 in the results.
Narrowing the Search Results
You can refine your search results across categories. To narrow down your results, select multiple values across different categories. The results will only include values that match the selections across the categories. For example, selecting “2005” in the “By Year” category and “NASA” in the “By Agency” category will only display the results that contain both “2005” AND “NASA” in the results.