Abstract:There are several techniques which can improve the performance of ASTROS. Among these are three that MAST will evaluate and commence implementation of: Improved optimization techniques using both gradient and nongradient based techniques suchas genetic algorithms, simulated annealing and the… more
Abstract:HAWAII HAS SEVERAL SPECIES OF EDIBLE MARINE LIMPETS CALLED OPIHI. THEY ARE ENDEMIC TO THE HAWAIIAN ISLANDS AND ARE HIGHLY PRIZED DELICACY SERVED AT SPECIAL OCCASIONS. THE NATURAL POPULATIONS HAVE BEEN DRASTICALLY REDUCED BY OVERFISHING, AND A ONCE THRIVING COMMERCIAL FISHERY HAS ALL BUT VANISHED.… more
Abstract:This proposal is to develop an innovative link between remote sensing, expert systems, and geographic information system technologies to environmental models. The Visual Environment Modeling and Analysis Tool (VEMAT) integrates 1) an image analysis expert system, 2) a geographic information system,… more
Abstract:Using ATR/C on a UAV is a general innovation which addresses the problems of data volume, complexity and timeliness. The opportunity is to use UAVs and provide onboard ATR/C algorithms which could be implemented in the hardware as an integral part of the sensor system and be programmable to focus on… more
Abstract:Benzodiazepines are in clinical use as antianxiety agents and are controlled substances. Prolonged use may be habit forming. Benzodiazepine abuse is a widespread problem. There is a practical need to screen for the presence of benzodiazepines and their metabolites. Oxazepam glucuronide is the final… more
Abstract:There is increasing awareness about the problems associated with blood transfusions. One concern isbacterial contaimination of blood bags. If contaminated blood is transfused, the person receiving thbecoming sick and dying. Current standards require that blood be visually inspected before leaving… more
Abstract:This project continues the investigation of Ultrasonic forces coupled with Field-Flow Fractionationseparate macromolecules and cells. A prototype Ultrasonic Field-Flow Fractionation apparatus has beefabricated and tested. The device is configurable in three modes. Retention has been demonstrated… more
Abstract:THE BLACK-LIP PEARL OYSTER, PINCTADA MARGARITIFERA, IS THE SOURCE OF RARE, VALUABLE BLACK PEARLS. CULTURE OF THIS SPECIES HAS PROVEN HIGHLY LUCRATIVE IN FRENCH POLYNESIA, WITH STRENGTHENING WORLDWIDE DEMAND. THE HAWAIIAN SUB-SPECIES, P. MARGARITIFERA GALTSOFFI, IS ON THE HAWAII STATE ENDANGERED… more
Abstract:NATIVE HAWAIIANS "FORM AN UNDERPRIVILEGED MINORITY BOTH IN HAWAII AND ON THE MAINLAND UNITED STATES, WITH CHARACTERISTICS SIMILAR TO NATIVE AMERICANS, BLACKS, AND HISPANICS" (ATU LIKE, 1989). THE NATIVE HAWAIIAN COMMUNITY HAS A HISTORY OF UNDERREPRESENTATION IN THE BUSINESS SECTOR. THE ULTIMATE… more
Abstract:MULTIPLE ACCESS PROTOCOLS ARE USED TO PERMIT LARGE NUMBERS OF INDEPENDENT TRANSMITTERS TO SHARE A SINGLE COMMUNICATION CHANNEL. THERE ARE THREE DIFFERENT TYPES OF MULTIPLE ACCESS PROTOCOLS WHICH ARE USED IN MOST WIRELESS DATA NETWORKS TODAY-TDMA, CDMA AND ALOHA. CDMA PROTOCOLS CAN BE EFFICIENT BUT… more
Abstract:Multiple access protocols are used to permit large numbers of independent transmitters to share a common communication channel. CDMA was developed as a multiple access network protocol for military applications during the last forty years. Recently considerable interest in using CDMA in the civilian… more
Abstract:THE OVERALL GOALS OF THIS PROJECT ARE TO DEVELOP IMMUNOASSAYS FOR THE DETECTION OF BRYOSTATIN 1 AND ITS ANALOGUES IN A VARIETY OF BIOLOGICAL MATRICES. THE BRYOSTATINS HAVE EXHIBITED STRONG ANTINEOPLASTIC ACTIVITY IN PRECLINICAL STUDIES AND ARE SCHEDULED TO ENTER PHASE I CLINICAL TRIALS LATER THIS… more
Abstract:Murine monoclonal antibodies which neutralize maitotoxin will be selected using a functionalassay that exploits the hemolytic action of maitotoxin. The resulting antibodies should be useful forseveral purposes. They will provide a means to measure the toxin content in crude extracts of fishtissues… more
Abstract:Dengue viruses are a leading cause of morbidity and mortality throughout the tropics andsubtropics. It is estimated that more than 100 million people in the tropics are infected annually by thisvirus. This threat has now reached the southern United States with the arrival of the Aedes… more
Abstract:Several fundamental parameters need to be addressed with regard to the development of biosensors. Protein stability is a major criteria for sensors devoted to long-term monitoring. The enzyme label is typically the most unstable componenet in biosensors. Additional problems encountered with… more
Abstract:The filamentous fungi, owing to their ability to secrete high levels of proteins, are attractive organisms for the expression and secretion of heterologous proteins of commercial and medical value. Secretion is a key element in their attraction, for secretion enables proper folding and processing of… more
Abstract:Natural testosterone and numerous synthetic analogs are known to stimulate biosynthesis ofproteins and are used as therapeutic agents. Most of them are DEA controlled substances. Improper usemay cause health risks. Steroid abuse is a widespread problem. There is a practical need to screen forabused… more
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