Abstract:DESCRIPTION (provided by applicant): Medicinal and computational chemistry methods will be used to optimize validated hit compounds found to inhibit botulinum neurotoxin. These inhibitors, discovered through in silico docking and confirmed with an in vitro fluorescence resonance energy transfer… more
Abstract:NovaSol proposes to develop an advanced hyperspectral imaging system for earth science missions named BRASS (Broadband Advanced Spectral System). BRASS combines state-of-the-art, existing NASA detector technology and proven electronics with a novel spectrometer design to provide a compact instrument… more
Abstract:NOVASOL is pleased to propose development of an algorithm for enhancing hyperspectral target detection performance in reconnaissance imagery using spectral detection combined with spatial processing of auxiliary panchromatic high-resolution imagery. The exploitation of both spectral and spatial… more
Abstract:Papaya is a major commodity in Hawaii. The Big Island accounted for about 35.7 million of harvested papaya for fresh utilization and 1.8 million pounds for processed utilization. Additional processed utilization of papaya would be valuable to the industry because culls average 30 percent of total… more
Abstract:In Hawaii, commonly used, expensively imported organic orchid growth media -- bark and coir -- quickly break down, inviting pathogens, pests and other problems for commercial orchid growers, who are striving to stay competitive amid global expansion in the orchid industry. Also, as an island state… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project aims to develop and validate a novel chloroplast transformation vector for protein expression in chloroplasts. The research project will broaden scientific understanding of the parameters of chloroplast transformation by addressing… more
Abstract:Plant chloroplasts are capable of producing significant quantities of high quality bioengineered proteins with biomedical applications. Improving the commercial supply of diagnostic antigens and vaccines through use of our pliable expression platform will provide an important technological advance… more
Abstract:Cold or tempurate weather limits the location and timing of shrimp farming. If Kona Bay Marine Resources can develop a cold-tolerant, disease-resistant shrimp, U.S. farmers will be able to significantly increase production by growing larger shrimp and reducing crop loss from disease. Ultimately,… more
Abstract:Maintain high market prices for farmed fish as production increasese with industry growth. Find means of preserving product from times of excess harvest without diminishing the brand value. Finally, to foster wider recognition for the product differentiation between open ocean farmed U.S. grown… more
Abstract:The target area has rural communities strongly desiring to maintain the agricultural base of the region through diversified agriculture. Green tea enjoys great popularity resulting from its association with positive health benefits. A Hawaiian branded product has been shown to have positive… more
Abstract:The Navatek, Ltd. Team will successfully demonstrate the feasibility of using Fiber Reinforced Composites (FRC) materials to significantly reduce the weight of the (hull) structure of the Littoral Combat Ship (LCS) Unmanned Surface Vehicle (USV). We will use as a baseline for comparison our… more
Abstract:Navatek Ltd. will successfully integrate their Integrated Propulsion Pod (IPP) technology to provide dynamic motion compensation to manned and unmanned surface vehicles to facilitate safe and effective launch, tow and recovery of tow bodies for up to and including a sea state 4 condition at various… more
Abstract:The objective of this proposal is to demonstrate the feasibility of producing a lighter, smaller and more efficient solid-state power amplifier for the JTIDS system that is flight qualified for the E2-D Advanced Hawkeye aircraft. Because space and weight is extremely critical aboard the E2-D Hawkeye… more
Abstract:The Small Business Innovation Research (SBIR) Phase II project will develop a novel high-resolution instrument capable of penetrating and imaging live cells down to the 50 nm resolution level. This can provide further insights into the molecular makeup of cells and may open new avenues toward the… more
Abstract:This Phase II proposal presents the design and development approach for a distributed Doppler-radar network system for sense-through-the-wall intelligence collection. Phase I research successfully demonstrated the proof of concept and yielded a viable path of development that will culminate in the… more
Abstract:In response to Army topic A052-080-1968, Oceanit Laboratories has proposed the Hostile Fire Detection System (HFDS), which will detect attacks from close range weapons and locate enemy combatants. HFDS is based on Oceanit's patented MOST focal plane. It utilizes a time-intensity identification… more
Abstract:The current project will develop and demonstrate a prototype compact, power-efficient all-fiber lidar unit for wind profiling on board UAV's and other aircraft. The system leverages Oceanit's current fiber-laser based lidar development efforts. A unique design provides a rugged system with no… more
Abstract:Open-Ocean Aquaculture businesses are proving commercially successful. There are several technical refinements the industry must undergo in order to maximize productivity and future expansion. We address a problem common to all off-shore open-ocean aquaculture cage systems, marine biofouling of… more
Abstract:A new approach is needed for effectively addressing the fundamental security requirement of authentication within a multi-national environment. The Cross Enclave Authentication Service (CEAS) will be secure, based upon the principle of `least privilege', with enforcement through discretionary and… more
Abstract:Technical Research Associates, Inc. proposes to develop Visualization Software for Multi- and Hyperspectral Imagery Exploitation. This Hyperspectral Visualization Environment (HVE) software will provide insight into hyperspectral and multi-spectral sensor data with maximum efficiency, by… more
Abstract:Current hyperspectral analysis, used to extract information related to nuclear fuel cycle signatures, relies on principal component and matched filter processing, which may not fully exploit all of the information in the data. This project will develop an innovative method for: (1) using… more
Abstract:Building upon the Edelman's Neural Darwinism and Damasio's brain model, we propose a framework for creating evolutionary and neurobiologically inspired computational platforms for autonomous vehicle control as well as for applications in the arena of ambient intelligence. Additionally, we propose… more
Abstract:An increasingly common military medical need is the need for in-the-field acquisition of symptomatology, differential diagnosis of diseases potentially previously unseen by the medical professional, and identification of symptoms to the population at large. This need suggests a combination of… more
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