Abstract:DESCRIPTION (provided by applicant): Ebola and Marburg viruses, the only members of the family Filoviridae, cause hemorrhagic fevers which are lethal in up to 90% of human cases. No vaccine or antiviral therapy currently exists to prevent or treat Filoviru
s infection. Due to their exceptional… more
Abstract:Satellites and other spacecraft are a key asset and critical vulnerability in our communications, surveillance and defense infrastructure. Space Situational Awareness (SSA) and Defensive Counterspace (DCS) efforts are aimed at leveraging the massive amounts of data gathered from ground, air and… more
Abstract:In the field of aircraft health management, the integration and availability of historical data from multiple data sources is necessary for diagnostic and prognostic algorithms to realize their full potential. Especially important is the integration of historical in-flight operational data with… more
Abstract:Red teaming is a technique that has been used successfully for some time in the military community to uncover system vulnerabilities or to find exploitable gaps in operational concepts, such as new weapon systems or tactics. Red teaming is currently a human intensive technique that typically brings… more
Abstract:Hyperspectral sensor systems are currently under consideration for applications related to monitoring the nuclear fuel cycle and other signatures of interest to the nonproliferation community. These applications include the detection of camouflaged and concealed targets, gas plume detection and… more
Abstract:To support its use of MEMS sensors for vehicle health monitoring, the Air Force seeks to couple the harvesting of ambient energy sources with a micro energy storage device. Microbatteries have demonstrated their viability as a high density power source, but their short operating life limits their… more
Abstract:Cacao trees grow and produce well in Hawaii. How can we develope cacao growing and chocolate production to best utilize this asset? This project research will help define the potential for cocoa production in Hawaii and whether sufficient high end gourmet cocoa products can be produced in a… more
Abstract:DESCRIPTION (provided by applicant): The strain of West Nile virus now endemic in the continental United States is more virulent than the virus originally isolated in Africa and is classified as a category B priority pathogen by the NIAID. In only six years, it has spread throughout the continental… more
Abstract:DESCRIPTION (provided by applicant): Over half of the world population is at risk for infection by dengue virus, a mosquito borne member of the Flavivirus family that consists of four distinct serotypes. Approximately 50 to 100 million infections occur annually resulting in an estimated 500,000… more
Abstract:DESCRIPTION (provided by applicant): Medicinal and computational chemistry methods will be used to optimize validated hit compounds found to inhibit botulinum neurotoxin. These inhibitors, discovered through in silico docking and confirmed with an in vitro fluorescence resonance energy transfer… more
Abstract:NovaSol proposes to develop an advanced hyperspectral imaging system for earth science missions named BRASS (Broadband Advanced Spectral System). BRASS combines state-of-the-art, existing NASA detector technology and proven electronics with a novel spectrometer design to provide a compact instrument… more
Abstract:NOVASOL is pleased to propose development of an algorithm for enhancing hyperspectral target detection performance in reconnaissance imagery using spectral detection combined with spatial processing of auxiliary panchromatic high-resolution imagery. The exploitation of both spectral and spatial… more
Abstract:Papaya is a major commodity in Hawaii. The Big Island accounted for about 35.7 million of harvested papaya for fresh utilization and 1.8 million pounds for processed utilization. Additional processed utilization of papaya would be valuable to the industry because culls average 30 percent of total… more
Abstract:In Hawaii, commonly used, expensively imported organic orchid growth media -- bark and coir -- quickly break down, inviting pathogens, pests and other problems for commercial orchid growers, who are striving to stay competitive amid global expansion in the orchid industry. Also, as an island state… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project aims to develop and validate a novel chloroplast transformation vector for protein expression in chloroplasts. The research project will broaden scientific understanding of the parameters of chloroplast transformation by addressing… more
Abstract:Plant chloroplasts are capable of producing significant quantities of high quality bioengineered proteins with biomedical applications. Improving the commercial supply of diagnostic antigens and vaccines through use of our pliable expression platform will provide an important technological advance… more
Abstract:Cold or tempurate weather limits the location and timing of shrimp farming. If Kona Bay Marine Resources can develop a cold-tolerant, disease-resistant shrimp, U.S. farmers will be able to significantly increase production by growing larger shrimp and reducing crop loss from disease. Ultimately,… more
Abstract:Maintain high market prices for farmed fish as production increasese with industry growth. Find means of preserving product from times of excess harvest without diminishing the brand value. Finally, to foster wider recognition for the product differentiation between open ocean farmed U.S. grown… more
Abstract:The target area has rural communities strongly desiring to maintain the agricultural base of the region through diversified agriculture. Green tea enjoys great popularity resulting from its association with positive health benefits. A Hawaiian branded product has been shown to have positive… more
Abstract:The Navatek, Ltd. Team will successfully demonstrate the feasibility of using Fiber Reinforced Composites (FRC) materials to significantly reduce the weight of the (hull) structure of the Littoral Combat Ship (LCS) Unmanned Surface Vehicle (USV). We will use as a baseline for comparison our… more
Abstract:Navatek Ltd. will successfully integrate their Integrated Propulsion Pod (IPP) technology to provide dynamic motion compensation to manned and unmanned surface vehicles to facilitate safe and effective launch, tow and recovery of tow bodies for up to and including a sea state 4 condition at various… more
Abstract:The objective of this proposal is to demonstrate the feasibility of producing a lighter, smaller and more efficient solid-state power amplifier for the JTIDS system that is flight qualified for the E2-D Advanced Hawkeye aircraft. Because space and weight is extremely critical aboard the E2-D Hawkeye… more
Abstract:The Small Business Innovation Research (SBIR) Phase II project will develop a novel high-resolution instrument capable of penetrating and imaging live cells down to the 50 nm resolution level. This can provide further insights into the molecular makeup of cells and may open new avenues toward the… more
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