Abstract:DESCRIPTION (provided by applicant): The purpose of this Phase I feasibility study to design, construct and evaluate an ultraminiaturized sensor device capable of detect ng protein biomarkers from a few cells and, ultimately, single cells. The device, termed the nanobiosensor, consists of an array… more
Abstract:Over the past 15 years, the emphasis on selecting for leaner pigs with larger loineye areas and high percent lean cuts has resulted in meat with lower water-holding capacity, lower intramuscular fat (IMF), and lower scores for juiciness, flavor and overall pork quality. Swine breeders need a genetic… more
Abstract:DESCRIPTION (provided by applicant): This is a revised application. The broad, long-term objectives of this Phase I STTR proposal is to demonstrate feasibility in developing a novel optical-electronic biosensor for microscopic applications to permit simultaneous integration of photonic and… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will make the creation of effective intelligent tutoring systems (ITSs) easier, and it will enable the dissemination of that technology to a broader audience than currently realized. ITSs have proven to be highly effective in delivering… more
Abstract:DESCRIPTION (provided by applicant): Title Support vector machines predict sequence ~ activity relationships in RNA interference Project Summary/Abstract Support Vector Machines (SVMs) are a group of algorithms in supervised machine learning that are able to build classification or regression models… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project aims to develop a next-generation microsensor for dissolved oxygen (DO) in water. DO sensors are a primary tool for gauging the quality of both fresh water (rivers, lakes, reservoirs) and the oceans; for monitoring the various processes… more
Abstract:DESCRIPTION (provided by applicant): Osteoarthritis and articular cartilage injuries are very common, typically causing pain, swelling and reduced mobility leading to functional impairment. The treatment cost for patients suffering from these conditions are massive with an estimated annual economic… more
Abstract:DESCRIPTION (provided by applicant): The availability of a reference human genome sequence provides the foundation for studying the genetic and molecular basis of human health and disease. Using a variety of modern technologies to study differential gene expression, large numbers of researchers in… more
Abstract:DESCRIPTION (provided by applicant): The Human Genome Project has brought the field of functional genomics to the forefront of biological and pharmaceutical research. However, deciphering the function(s) of each gene in a high throughput format is complicated by alternative splicing and post-… more
Abstract:An ad-hoc networking method is proposed for use over existing power lines in large commercial buildings. The network is minimally sensitive to lossy elements such as distribution transformers and tripped or OFF circuit breakers and hardware may be made interoperable with existing power line… more
Abstract:The miniature ESM receiver payload from Phase I will be prototyped into both an ESM and communications relay payload with low profile broadband antenna and high speed miniature TCDL Ku-band downlink. All aspects of the payload are very lightweight, small, low power, and inexpensive commensurate… more
Abstract:Weight-sensitive shipboard and transportable systems in support of deployed operations require high RF test analysis capability in the 100 KHz to 26.5 GHz range. It is highly desirable to implement this as a miniature PXI module suite for the Navy's Automated Test Systems that combines the modular,… more
Abstract:The proposed S-band telemetry transmitter will operate in the exterior Venusian high pressure, 465?aC ambient atmosphere without being contained in a thermally protective container. The sealed, radiation-hardened, high-reliability, silicon-carbide-based transmitter uses an ambient heatsink to cool… more
Abstract:The problem to be solved is developing an affordable receiver system for ionospheric measurements. The challenges lie in developing a low-cost node that enables deployment of a large measurement grid to measure the spatial distribution of signal reflections over a substantial geographic area;… more
Abstract:The lack of proper estimation of air loads encountered during transient maneuvers introduces excessive design conservatism. This proposal offers to develop a computational tool, based on the lower order momentum source rotor model, capable of analyzing steady and transient maneuvers. This tool… more
Abstract:This project is to develop versatile, low mass, energy efficient, and easily maintained multipurpose seed processing (MSP) equipment for food processing in space environments. Phase-1 of the project yielded a conceptual drawing for a MSP. Phase-II consists of six main tasks. The first model MSP… more
Abstract:This Phase I research proposal is aimed at demonstrating the feasibility of an innovative architecture comprising control augmentation and on-line health monitoring system. This architecture integrats Flush Air Data System (FADS) with Reconfigurable Generalized Predictive Control (RGPC) technologies… more
Abstract:DESCRIPTION (provided by applicant): VIDA Diagnostics is taking a leading role in pioneering new image display and analysis tools which take advantage of the rapid advancements in multi-row detector computer tomography (MDCT) of the chest. The company is providing software solutions for the image… more
Abstract:DESCRIPTION (provided by applicant): Phase I The current proposal describes the selection of an aptamer that recognizes the drug PD173955, which is one of large family of substituted pyrido[2,3-d]pyrimidine inhibitors of tyrosine protein kinases. An aptamer is a single stranded nucleic acid that… more
Abstract:The invasion of woody vegetation into native plant communities is a growing problem on many of the Nation's rangelands, resulting in the loss of pastureland and the need to make alterations in livestock management. The Loess Hills of Western Iowa have been severely impacted by ERC and other… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project addresses the difficulties of authoring intelligent tutoring systems. Intelligent Tutoring Systems have proven to be highly effective in delivering computer-based instruction, but have historically been expensive and difficult to build,… more
Abstract:DESCRIPTION (provided by applicant)
Cyntelix, Inc. in collaboration with the Hazardous Materials Training and Research Institute (HMTRI) at Kirkwood Community College will undertake the Hazard Response Technology (HaRT) Case Study Training Innovation Project. The goal of the HaRT Training… more
Abstract:DESCRIPTION (provided by applicant): Osteoarthritis and articular cartilage injuries are very common, typically causing pain, swelling and reduced mobility leading to functional impairment. The treatment cost for patients suffering from these conditions are massive with an estimated annual… more
Abstract:Egg breakage and cracking is a major economical problem for the US poultry industry which can affect up to 10% of the eggs produced. The resulting approximately 500 million dollars in lost revenue to producers is a cost ultimately borne by consumers. To minimize damaged eggs, producers have… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project proposes to develop sex pheromone-based techniques for monitoring, mass trapping, and mating disruption of the soybean aphid. Since its first appearance in North America, infestations of the newly invasive soybean aphid, Aphis glycines… more
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