Abstract:Today\'s submarine towed array handling system operating parameters an methods are equivalent to those used in the late sixties. Attempts to utilize conventional cable handling methods are not suitable for array handling, and appropriate methods have not yet been defined. Outboard system volume,… more
Abstract:LIQUID CRYSTAL MATERIALS HAVE BEEN INVESTIGATED IN THE PAST FOR DETECTING AND VISUALIZING ULTRASOUND IMAGES. HOWEVER, BECAUSE OF THEIR LIMITED DETECTION SENSITIVITY, THE RESULTING "ACOUSTO-OPTICAL" DISPLAYS HAVE NOT BEEN INVESTIGATED FOR MEDICAL IMAGING PURPOSES. RESEARCHERS ARE DEVELOPING NEW… more
Abstract:Galactosyl ceramide (GalCer) acts as an alternative receptor for HIV in CD4 negative cells throughto the HIV envelope glycoprotein gp 120. The design and synthesis of GalCer analogs capable of bindiblocking its interaction with GalCer is potentially a powerful therapeutic approach against HIV… more
Abstract:We will develop a regulated expression system for the extreme thermophile Thermus flavus. This systproduction of commercially important thermostable enzymes. In the Phase I feasibility study we willfrom Thermus, perform minimal structural analyses, and test their regulation using reporter genes… more
Abstract:We propose to develop a what-if analysis tool for hardware/software co-design. It will provide a test-bed in which the user can quickly evaluate hardware/software co-design trade-offs. No tool currently available in the ESDA market supports this essential step in hardware/software co-design. … more
Abstract:PAVEMENT DISTRESS DATA ARE UTILIZED DURING PAVEMENT EVALUATION, DESIGN, REHABILITATION, MAINTENANCE, MANAGEMENT, AND RESEARCH. CURRENTLY, THE MANUAL SURVEY METHOD, UTILIZING PAPER AND PENCIL, IS USED EXTENSIVELY IN COLLECTING THE DISTRESS DATA, BUT THIS PROCESS IS SLOW, TEDIOUS, EXPENSIVE, AND PRONE… more
Abstract:Ganuna (7)-ray lenses are an advanced technology currently under development at Argonne National Laboratory for arms control application. The purpose of this proposal is to address whether y-ray lens technology can enable an improved system for imaging radioactive isotopes in patients. In nuclear… more
Abstract:Accurate measurement of gastrointestinal absorption of various substances is important in bothresearch and diagnosis. In many cases, the acceptable general approach is the balance procedure. Thisprocedure suffers from the requirement for complete collection of stools over an extended period oftime.… more
Abstract:1We are proposing a computerized tomographic (CT) dimensional measurement system that will remedy two of the major problems experienced by current methods: the distortions caused by CT artifacts, and the blurring caused by the system point - spread function (PSF). The distortions resulting from data… more
Abstract:Instrumentation that can provide microstructural characterization of medical grade polymers,fabrics, and composite materials is the proposed research's long term goal. One micron resolutionvolume computed tomography of test specimens can now be demonstrated by combining anNIST-developed x-ray… more
Abstract:We will adapt a non-cryogenic magnetic field sensor previously developed for defense purposesand apply it to magnetocardiography (MCG), the measurement of magnetic fields induced by electricalcurrents in the heart. As a single non-invasive sensor, this unit would have similar applications to… more
Abstract:The proposed innovation is to apply differential phase acoustic microscopy to NDE inspection of ceramic Sn3N4 ball bearings. Differential phase acoustic microscopy is more sensitive than standard acoustic microscopy, and can provide the location and size of defects, which is a specific goal of the… more
Abstract:We propose a method of generating x-rays that will combine high instantaneous output of rotating-anode x-ray tubes with continuous cooling rates as great or greater than fixed-anode tubes. This combination can be achieved in a mechanically simple way, and will reduce spot wobble without vacuum seals… more
Abstract:We have generated a monoclonal antibody, B6B21, and have shown that it significantlyenhances acquisition rates in hippocampus-dependent trace eyeblink conditioning in rabbits, halving thenumber of trials required to reach 80% conditioned responses. Previous studies, with a variety of modelsystems,… more
Abstract:We will develop a computer simulation of the critically ill patient for use in training medical students, residents, nurses, fellows, and physicians. This computer software will faithfully simulate the functional aspects of cardiopulmonary physiology, using state-of-the-art mathematical models. For… more
Abstract:We propose to develop a general purpose computer code for calculating the scattering from antennas on an aircraft, which is described by a CAD file. The scattering contribution will include both the passive structure mode and active irradiation mode, calculcated by a hybrid of a high-frequency ray… more
Abstract:Elderly women and men are at higher risk for developing skin cancers, as a result of theirincreased cumulative exposure to ultraviolet radiation, and their depressed immune system functioningrelative to younger persons. Interactive multimedia materials providing information about skin lesionsand… more
Abstract:The incidence of skin cancer is increasing at a high rate. Skin cancers are uniquely suited forprevention and early detection interventions in that adequate sun protection can prevent occurrence andscreening can reduce morbidity and mortality. This interactive multimedia program is intended… more
Abstract:U.S. ARMY CECOM HAS IDENTIFIED THE NEED TO DEVELOP AND DEMONSTRATE IMPROVED TRANSPORT TECHNOLOGIES FOR MULTIMEDIA C3 COMMUNICATION SYSTEMS. BENEFITS TO BE OBTAINED INCLUDE ENHANCED SECURITY AND ANTI-JAM SURVIVABILITY, HIGH DATA FLOW EFFICIENCY AND GREATER USE OF WIRELESS TO REPLACE HARD CABLED… more
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