Abstract:DESCRIPTION (provided by applicant): The objective of this Phase II SBIR application is to test NTX-1 fiber in patients with constipation-predominant IBS (IBS-C) and determine if it can reduce symptoms, beneficially modify gut microbiota composition, and improve gut milieu in these patients. Our… more
Abstract:DESCRIPTION (provided by applicant): Over 8 million Americans have peripheral vascular disease (PAD). Percutaneous transluminal artery (PTA) treatment of severe PAD involves the use of balloons and stents, but delivery of these therapies is often suboptimal due to inaccuracies in angiographic… more
Abstract:DESCRIPTION (provided by applicant): Transseptal (TS) access for left heart procedures is an important and rapidly growing space for diagnostics and therapy delivery with an expected total of over 10 million U.S. patients. In the U.S. and/or Europe, TS access procedures are used for atrial… more
Abstract:DESCRIPTION (provided by applicant): Coronary artery disease (CAD) is a national and worldwide epidemic that places the largest clinical and economic burden on the healthcare system of any disease condition. Patients with stable and acute coronary conditions are often treated with percutaneous… more
Abstract:ABSTRACT: The program will focus on the design and development of a compact, high efficiency C-Band telemetry transmitter. The transmitter will be capable of transmitting in three separate sub-bands. The user will be able to select the band of operation as well as the desired ARTM waveform. LTCC… more
Abstract:This proposal is focused on the development of very wide bandwidth, high efficiency power amplifiers for next generation EW, radar and wireless communication systems. High-Q tunable notch filters, coupled with high efficiency power appliers (PA) will be designed and analyzed. The PA-filter co-design… more
Abstract:The proposed project will focus on the development of closed loop frequency control hardware and algorithms for control of high quality factor tunable microwave filters based upon evanescent mode resonators. The developed controller will be integrated with a representative filter. As a system… more
Abstract:This project will develop tunable notch filter for the mitigation of co-site interference and jamming sources. The novel filter technology explored in the Phase I program has displayed excellent potential to provide wide tuning capability, low out-of-band insertion losses, deep notch depths, compact… more
Abstract:DESCRIPTION (provided by applicant): Over one million prostate biopsies are performed in the US each year to diagnose approximately 200,000 cases of prostate cancer. The majority of these biopsies are performed needlessly. The overall objective of this project is to develop a secondary prostate… more
Abstract:Project Summary / Abstract - EY020017 Phase IIB Competitive Renewal The overall goal of the proposed SBIR program is to implement and evaluate a low cost, portable retinal camera, the DLP-Cam, in a primary care system for diabetic retinopathy (DR) screening. Untreated DR has reached epidemic levels… more
Abstract:DESCRIPTION (provided by applicant): For dental and other applications there is a great need for self-filling tissue expanders with the capacity to be reshaped to fit the void by the surgeon at time of implantation. Akina recently completed an initial Phase II study using its hydrogel-based… more
Abstract:Navy ships use of gas turbine engines for both main propulsion and shipboard electrical power generation. With a typical simple cycle gas turbine nearly 65% of the energy consumed is typically lost as waste heat. Safely and efficiently recovering electrical power from this source of energy equal to… more
Abstract:DESCRIPTION (provided by applicant): An estimated 36 million US citizens have impaired hearing, but only one in five has had a hearing test. As noted by a recent NIDCD Working Group, In the US there are no readily accessible low-cost hearing screening programs. The authors of this proposal, in… more
Abstract:Ironically people who are blind or have visual impairments that should benefit the most from technology, have great difficulty in interacting with modern home appliances and electronics. This is primarily due to a combination of a lack of accessible features, device complexity, or the lack of a… more
Abstract:Currently, there is no suitable method of monitoring the mass flux of particulate material such as flour, sugar, chocolate chips, etc. for a continuous production process. Therefore, many of the food products are manufactured using batch processes, with very high inefficiencies and wide variation in… more
Abstract:This Small Business Innovation Research Program (SBIR) Phase I project will evaluate the feasibility of utilizing a low-resolution X-Ray tomography system in tandem with a coded aperture scheme to obtain highly resolved profiles of deep holes. Three tasks are planned during the Phase I work: The… more
Abstract:ABSTRACT: Desired tactical requirements for unmanned aerial systems (UASs) exceed current capabilities for performance, reliability, maintainability, cost and supportability. Mission requirements such as extended endurance, increased power for auxiliary/sensor systems, and low altitude, low speed… more
Abstract:DESCRIPTION: Development of an Intelligent Sample Introduction System for Mass Spectrometry There is a pressing need for new technologies that enable rapid measurements without significant compromise to the analytical data. Herein, we propose to develop arobust mass spectrometry (MS) based surface… more
Abstract:Operation of turbine engines in marine environments presents a great challenge for bearings and gears composed of Pyrowear 675. The harsh environment reduces bearing life and increases unscheduled maintenance. IBC Materials is developing an industrial-scale, novel thermal process utilizing a unique… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project proposes the creation of a mixed-criticality Java virtual machine (VM) and native code hypervisor of unprecedented flexibility and capability. Current generation mixed-criticality systems rely on proprietary and expensive operating… more
Abstract:DESCRIPTION (provided by applicant): Our long-term goal is to develop a novel therapeutic strategy for childhood acute lymphoblastic leukemia (ALL), with focus on relapsed T-cell leukemia. We intend to accomplish this by targeting a unique molecular masterregulator using a new generation of… more
Abstract:ABSTRACT: The Air Force is seeking a compact, high torque, rotary EMA technology capable of controlling flight control surfaces directly at the hinge line in the next generation of thin-wing aircraft. Proposed for this application is an advanced EMA technology based on an axial flux,… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will develop the use of unique artificial protein sequences, known as entropic bristles, to accelerate the study of protein structure by the method of X-ray crystallography. Many interesting proteins have proven to be difficult to… more
Abstract:The development of Wide Bandgap Semiconductors such as GaN has enabled tremendous improvements in power amplifier performance such as operational frequency and output power. These device improvements have in turn enabled performance and capability improvements in the end applications such as EW… more
Abstract:Failures in aircraft electrical power systems can compromise the readiness, safety, and capabilities of the war-fighter. Furthermore, if the root cause for the failure cannot be quickly identified, this can lead to increased maintenance costs and potential downtime for the aircraft. In this effort,… more
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