Abstract:Although taxol, paclitaxel, is one of the most promising anticancer drugs, the supply of taxol hasmarket demands. To date taxol production is limited and dependent on extraction from bark of yew treChemical synthesis of taxol gives low yield, semi- synthetic production requires a very large… more
Abstract:A large and growing number of the residents of the United States speak English as a secondlanguage. Opportunities for employment, promotion, and education for this population can be negativelyaffected by their inability to communicate effectively in English. Little is known, however, about… more
Abstract:Every year approximately 16,000 to 20,000 school age children sustain traumatic brain injuries (TBIimpairment of cognitive abilities and physical functioning. The innate ability of TBI students to leenvironment is compromised because of their difficulty in receiving, processing, and storing new… more
Abstract:Our objective is to create a female rat model which exhibits Non-Insulin Dependent Diabetes Mellitus (NIDDM). Literature supports that our diabetic, fatty male rat as superior to other available rat models in the onset and level of diabetes expressed. Characteristics such as pancreatic insulin… more
Abstract:The proposed research entails the development of a pulsed power driver capable of producing an electrical pulse with peak currents greater than 200 amps, peak powers greater than 200 kilowatts, and repetition rates greater than 10 kHz. MellWood Laboratories, Inc. has developed an entirely solid… more
Abstract:Cold cathode devices capable of emitting electrons into a vacuum without relying on high temperature thermionic emission are expected to play an important role in a wide variety of applications ranging from high frequency, high power amplifiers to flat panel displays. Cold cathode devices based on… more
Abstract:Acetaminophen and salicylates are contained in over 200 prescription and non-prescriptionformulations. Of all intentional and unintentional overdose ingestions of pharmaceutical andnon-pharmaceutical compounds, those of acetaminophen and salicylates are the most frequent, both innumber of exposures… more
Abstract:THE USE OF EDDY CURRENTS TO DETECT SURFACE-BREAKING DEFECTS IS WELL ESTABLISHED, AND MUCH KNOWLEDGE HAS BEEN BUILT UP IN ANALYZING THESE SIGNALS. HOWEVER, THE THEORETICAL BASIS FOR THIS TECHNIQUE IS UNDER-UTILIZED OR IGNORED. THE ELECTROMAGNETIC EQUATIONS TO BE SOLVED ARE COMPLEX, AS REALISTIC… more
Abstract:The need to recycle solid plastic waste is becoming increasingly acute in view of the limited availability of both landfill space in which to dump plastic trash and the petroleum reserves needed to replace discarded material. The National Research Council has identified the need for a rapid and… more
Abstract:Acute hepatic failure (AHF) with Stage 4 coma is a serious illness with over 60% mortality when tresupportive therapy. The BioLogic-DT is an extracorporeal liver support device which uses the membranplate dialyzer to propel blood through a single access and circulates a suspension of powdered… more
Abstract:We will apply thoracic electric bioimpedance monitoring by external electrodes (TEB) to those patieunstable on hemodialysis and find a primary cardiovascular parameter which predicts the onset of symOur expectation is that percent fall in cardiac output will be the primary indicator, but we will… more
Abstract:ADIABATICS, INC. IS PLEASED TO PROPOSE A RESEARCH PROGRAM TO DEVELOP A NOVEL "COMPACT, MINIMUM NOISE, AUXILIARY POWER UNIT (APU) FOR LIGHTWEIGHT VEHICLES." THE APU USES A COMMERCIAL DIESEL ENGINE AND AN ADVANCED GENERATOR AND NOVEL COOLING TECHNIQUES TO MEET THE STATED REQUIREMENTS. THE KEY… more
Abstract:IN THE FUTURE, AUTOMATED MACHINERY WILL REQUIRE DISTRIBUTED INTELLIGENT ACTUATORS, SENSORS AND CONTROLS. THIS PHASE I EFFORT WILL PRODUCE A CONCEPTUAL DESIGN FOR AN INTEGRATED SET OF LIGHTWEIGHT, LOW-COST, MODULAR, INTELLIGENT CONTROLLERS AND SPEED REDUCERS FOR USE IN A VARIETY OF AUTOMATION AND… more
Abstract:THIS PROJECT IS PURSUING THE DESIGN AND PRODUCTION OF A LINE OF INTEGRATED MECHANICAL, ELECTRONIC, AND SOFTWARE MODULES TO PROVIDE A LOGICAL FRAMEWORK WITHIN WHICH MOTION CONTROL SYSTEMS OF GREAT EFFICIENCY AND VERSATILITY MAY BE DESIGNED AND CONSTRUCTED. THESE PRODUCTS ARE CALLED GENERAL-PURPOSE… more
Abstract:Traditional project management relies on hierarchically structured projects. As organizations decentralize, the need for distributed planning increases concomitant with a greater need for communication. Operations planning through distributed simulation has been shown to be an appropriate means of… more
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