Abstract:DESCRIPTION (provided by applicant): New approaches are needed to improve the treatment options of over 50 million people in the United States suffering from chronic pain. The proposed research is designed to develop a novel class of opioid analgesicsthat produce less tolerance and may… more
Abstract:DESCRIPTION (provided by applicant): This overall goal of this project is to develop a scalable process for fabricating oil encapsulated particles with uniform sizes and physical characteristics that contain oil as a vehicle for delivering hydrophobic drug
s. Poorly water soluble active… more
Abstract:Manufacture and maintenance of aircraft, ships, light rail cars, etc., requires many structural components formed out of extrusions. Processes such as stretch forming are typically used to produce these parts, in which unique dies are required for each forming operation. This increases the cost… more
Abstract:This Small Business Innovation Research (SBIR) Phase I research project is aimed at evaluating the impact of using multi-player educational video games in the classroom to improve student engagement in elementary school math subject areas, and developing an educational game system that enables… more
Abstract:Acidosis in ruminant animals (beef cattle, dairy cows, and sheep)is a metabolic condition that causes problems for animals fed high-grain diets. Orally dosing animals with a strain of bacteria, Megasphaera elsdenii, has been shown to be beneficial in alleviating or decreasing this metabolic problem.… more
Abstract:DESCRIPTION (provided by applicant): The proposed effort is aimed at the development and evaluation of a wireless electronic location system for reporting the location of individuals with autism and other cognitive disabilities, who may wander or elope. Th
is is a very vexing and routine problem for… more
Abstract:Early diagnosis and treatment of cancer greatly improve the likelihood of long-term survival and health. In Phase I, NanoScale Corporation and its partners at Kansas State University developed functionalized cancer-seeking "stealth" Fe/Fe3O4 core/shell nanoparticles, and demonstrated… more
Abstract:The end of the Cold War left the DOE with a surplus of nuclear facilities, which must now be deactivated and decommissioned (D&D). Appropriate protective apparel capable of shielding workers against a variety of hazardous materials such as airborne plutonium, mercury, organic solvents, asbestos, and… more
Abstract:This proposal details the development of a new FCG design that reduces energy losses for small package sizes. It addresses the major performance limiting factors associated with small helical FCGs and facilitates driving high output voltage, moderate current loads directly, without the need for a… more
Abstract:Application of agrochemicals is essential to U.S. production of food, fiber, biofuels and ornamentals. However, it can also create environmental contamination if pesticides reach non-target areas through airborne displacement of spray, i.e., "spray drift". Drift is a concern for agriculture,… more
Abstract:Could the future military use of UAV create a revolution in military affairs as great as the introduction of the airplane or the tank? Is the revolution underway now? If so, how can we best prepare our military for success? The advent of Unmanned Aerial Vehicles (UAV) is once more changing present… more
Abstract:DESCRIPTION (provided by applicant): The purpose of this fast-track SBIR project entitled Paragraph and Essay Writing Instruction for Struggling Secondary Writers is to develop and evaluate the effectiveness of a total of four interactive multimedia (IM)
software programs to be used to teach… more
Abstract:The need for detection of spoofind of ADS-B messages in real-time in an organic manner is discussed. Details of previous experiments demonstrating such spoofing are presented. A novel method to detect such spoofing detection capability from an airborne platform, in real time are presented. The… more
Abstract:High efficiency, low pollution, and long lifetime make hydrogen-powered fuel cells desirable for portable power generation by the Army. However, it is impractical to transport hydrogen to where it is needed. Instead, reforming a transportable liquid fuel such as JP-8 or diesel fuel can produce the… more
Abstract:The proposed research incorporates several inventions to produce structural components that can be assembled into a highly enhanced chemical-biological (CB) forensic evidence container for transport and storage of contaminated articles. Bio-hazardous materials are frequently encountered in standard… more
Abstract:Detection and identification of toxic chemical in water is vital for various military, environmental, and industrial applications. Specifically, the Joint Services have a need for rapid detection of trace levels of chemical contamination in water systems. This Small Business Technology Transfer… more
Abstract:Spacecraft and lunar bases generate a variety of wastes containing water, including food wastes, feces, and brines. Disposal of these wastes, as well as recovery of water, is necessary. However, evaporation of water also evaporates compounds with foul odors, some of which are much more volatile… more
Abstract:This Small Business Innovation Research Phase I effort focuses on development of novel metal-oxide-carbon nanocomposites for application in pseudocapacitive electrochemical supercapacitors. Specifically, nanocomposites based on manganese, titanium, tantalum and vanadium oxides will be incorporated,… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project, will develop a new kind of wafer cleaning tool that will be useful at every cleaning step in semiconductor processing. It will use an environmentally friendly, acoustic technology that uses only clean water and silent sound. The tool… more
Abstract:Crop growers in the United States, and in developed countries worldwide, apply large amounts of phosphate fertilizers to their fields. In the US for example, growers annually apply over 4,000,000 tons of phosphate fertilizer. Fertilizer rates are typically applied in excess of the crop need, since… more
Abstract:Nitrogen affects proteins, enzymes and metabolic processes and is essential for crop growth. While annual usage varies based on world economic conditions, approximately 80,000,000 metric tons of fertilizer N are applied annually in the world, of which more than 10,000,000 tons are applied annually… more
Abstract:This proposal details the development of a new FCG design that facilitates customization to drive loads of various impedances. It addresses several of the performance limiting problems associated with small helical FCGs and potentially facilitates driving high output voltage, moderate current loads… more
Abstract:Recent advances in directed energy weapons (DEW) require radar systems to implement front door protection against high power signals. Although nonlinear protection elements have been successfully employed in the past, fast ultra wideband (UWB) and high power microwave (HPM) signals are not… more
Abstract:DESCRIPTION (provided by applicant): The long range goal of this project is to develop methods of using supercritical carbon dioxide (scCO2) to achieve terminal sterilization that meets or exceeds the USP standard of 10-6 microbial survival probability and
that produces a dry drug product in a… more
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