Abstract:This Small Business Innovation Research Phase I project focuses on the development and implementation of a nanoparticle metal-oxide based collection, neutralization, and preservation of battlefield materials and evidence of a chemical and/or biological agent. The key component of the proposed… more
Abstract:DESCRIPTION (provided by applicant): Flourescence in situ hybridization (FISH) is a diagnostic test that distinguishes chromosomal abnormalities not evident by routine chromosome banding. By tagging and hybridizing defined DNA sequences with fluorochromes, abnormalities can be detected for specific… more
Abstract:Army vehicles require aggressive protection from rust and corrosion during long-term storage. MIL-PRF-21260 specifies a preservative/break-in oil to preserve a vehicle engine for an indefinite storage period, then drive it into service. MIL-PRF-2104 specifies a separate engine oil for in-service… more
Abstract:Surfaces Research proposes development of a highly durable solid lubricant coating to eliminate wear and vibration problems in liquid hydrogen turbopump gears. The cryogenic turbopumps are used in rocket engines for Air Force expendable launch vehicles. Our new coating will exceed the cryopump… more
Abstract:The U.S. Navy is seeking innovative concepts to substantially improve life of grease-packed hanger bearings on the tilt-rotor V-22 Osprey aircraft. Hanger bearings are especially maintenance-intensive and short-lived. Extending maintenance intervals and increasing bearing life several-fold are goals… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will develop new capability to model emergency egress from buildings. The primary focus of the research is evacuation due to fires, but the software will be designed such that exposure and response to biological and chemical agents can… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project concerns Ultrapure Water (UPW), the lifeblood of the semiconductor industry. The proposed instrument seeks to satisfy the International Technology Roadmap for Semiconductors (ITRS) requirements on two counts: 1. full flow inspections, 2.… more
Abstract:76063S International initiatives are underway to reduce greenhouse gases in the air. The sequestration of carbon in agricultural soils is a candidate technology for achieving this reduction; however, more rapid and less expensive methods of measuring soil carbon are needed. This project will… more
Abstract:DESCRIPTION (provided by applicant): The long-term objective of this work is to design bi-functional peptide-drug conjugates that specifically target leukocytes. The peptide sequences are derived from ICAM-1 and bind to LFA-1 on activated leukocytes. The peptide-drug conjugates are internalized… more
Abstract:Natural flavor compounds find wide applications in the food, feed, cosmetic, chemical and pharmaceutical industry, and isoamyl acetate is an important flavor ester. In this research program, a low-cost process is proposed to convert glucose from renewable sources to isoamyl acetate using a… more
Abstract:DESCRIPTION (provided by applicant): Paclitaxel has shown promise in the treatment of several types of cancers, including ovarian cancer. The long-term goals of this research are to design a formulation of paclitaxel that is effective in the treatment of cancer and exhibits no formulation related… more
Abstract:DESCRIPTION (provided by applicant): The purpose of this Phase I project is to test the feasibility of using an interactive multimedia (IM) format for delivering professional development to adults tutors and paraprofessionals who work with students with LD and low achievement. To evaluate the… more
Abstract:DESCRIPTION (provided by applicant): The purpose of this project is to design and pilot test a prototype interactive multimedia (IM) program for teaching social skills to youth with social-adjustment problems. The instructional program will be designed for use in a variety of settings, including… more
Abstract:A novel approach to conducting long-range surveillance using small unmanned air vehicles is proposed. The effort builds on the concepts developed and demonstrated in Phase I. This includes air vehicle technology, data links, flight operations, sensors and communications networks. A detailed work… more
Abstract:A method for providing endurance enhancement for unmanned aerial vehicles based on atmospheric phenomena is presented. The proposed method allows the UAV to sense certain atmospheric phenomena, and adapt itself to exploit these phenomena. The Phase I effort consists of understanding the physics of… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will develop and demonstrate a MEMS-scale integrated microfluidic fuel injector for small internal combustion engines to improve their efficiency. This will allow the use of these engines in small autonomous aircraft for long endurance… more
Abstract:75853-Carbon cycle monitoring is a key component of the mission to understand global-scale climate change. In particular, there is a need to accurately measure atmospheric carbon dioxide levels at regular intervals, and at various altitudes and locations, using low cost and simple aerial platforms.… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will develop and demonstrate capable and reliable autonomous aerial platforms for geoscience missions. This will allow relevant scientific data to be gathered via remote, autonomous means, providing timely atmospheric and environmental… more
Abstract:The need for a small tube launched UAV is presented. Such a UAV would allow pilots of the delivery platform to remain several miles away from harm's way. A few candidate concepts are presented, which would allow stand-off delivery of small UAVs for close-in data gathering. In addition to vehicle… more
Abstract:DESCRIPTION (provided by applicant) The innovative use of a synthetic peptide to modulate epithelial cell-cell interactions is proposed for the augmentation of drug- or gene-based therapeutic interventions. Cell monolayers are a major obstacle to delivering drugs to selected locations throughout the… more
Abstract:Although the surface decontamination of parts / equipment exposed to chemical and biological warfare agents takes place at forward operating areas, there is need for a system to eliminate the possibility of exposure to repair depot personnel and facilities from contaminated parts / components (e.g.,… more
Abstract:There is a growing need for improved sorbents that can be incorporated into chemical protective clothing, filtration materials, gas masks, etc. for protection from chemical hazards. The primary objective of this project is to develop a new composite sorbent material to address protective needs in… more
Abstract:DESCRIPTION (provided by applicant): This project will lay the groundwork to investigate the untapped potential of highly adsorbent and reactive nanoparticles in the area of protective garments manufacturing. The overall objective of this collaborative
Phase I research between NanoScale and… more
Abstract:During Phase I, Pinnacle Technology Inc. and Aviation Simulation Technology Inc. (AST) designed a distributed digital input/output (I/O) bus to replace the cumbersome discrete wire bundle used in all military and commercial flight simulators. After analysis of latency, compatibility with existing… more
Abstract:DESCRIPTION (provided by applicant): Pinnacle Technology and Dr. George Wilson of the University of Kansas will design a sensor suite capable of measuring physiologically relevant levels of glutamate, in vivo, in untethered small animals, with high spatial resolution and under ischemic conditions.… more
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