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Displaying 276 – 300 of 517 Awards
Company: SEQUELA Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION: This proposal is submitted in response to the program announcement PA-03-123 "Development of diagnostic screening test for salt sensitivity (SBIR/STTR)" from the National Institute of Diabetes and Digestive and Kidney Diseases. The overall hypothesis of our laboratory is the principle… more
Company: Tribo Flow Separations, LLC Agency/Program/Year/Phase: NSF / SBIR / 2005 / 2
Abstract: This Small Business Innovation Research (SBIR) Phase II project aims to develop a prototype Automated Foam Index Test (AFIT) instrument for measuring foam indices of mineral admixtures used in concrete; and, a prototype AFIT instrument for controlling dosage of air entraining agents into mineral… more
Company: THORTEK INNOVATIONS LABORATORIES Agency/Program/Year/Phase: DOD / SBIR / 2005 / 1
Abstract: Contemporary electric vehicle propulsion systems are heavy, bulky, and are not efficient which results in thermal management problems plus the inverter drive-controller restricts cabin space for passengers and cargo. A high power density, robust, scalable electric traction motor that is integrated… more
Company: TRANSPOSAGEN BIOPHARMACEUTICALS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant): Transposagen is developing an innovative mammalian random mutagenesis system that uses an L1 retrotransposon for direct germ-line mutagenesis. Transposagen's goal is to produce "mutator rats". In these rats, mutagensis will occur in sperm and some offspring will… more
Company: Vitatech, LLC Agency/Program/Year/Phase: HHS / SBIR / 2005 / 2
Abstract: DESCRIPTION (provided by applicant): Adenosine triphosphate (ATP) is the universal energy currency of the body and is made in large amounts by cells using substrate and oxygen. In the absence of oxygen, such as in disease states or surgical procedures that affect oxygen delivery, sufficient… more
Company: Vitatech, LLC Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant): Major limitations in liver transplantation are primary graft failure leading to consumption of the already small donor pool. ATP depletion has been proposed to be involved in graft failure due to both prolonged storage and to transplantation of marginal fatty… more
Company: APOIMMUNE, INC Agency/Program/Year/Phase: HHS / STTR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): Cancer continues to be a leading cause of death in the U.S. and in many other countries. Cancers develop and spread within the body when tumor cells are not detected or destroyed by the immune system. Although certain new therapies hold promise, current cancer… more
Company: BIOMEDICAL DEVELOPMENT CORPORATION Agency/Program/Year/Phase: HHS / STTR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): Poison ivy/oak dermatitis (also known as Toxicodendron dermatitis) is the most common allergic contact dermatitis in the United States, affecting millions of Americans every year. The prevalence of poison ivy and oak sensitivity in the general adult population… more
Company: BIOMEDICAL DEVELOPMENT CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): Treatment of hypertrophic scars and keloids is time consuming, expensive, and has few consistently successful approaches. Hypertrophic scars and keloids are often treated with intralesional injection, pressure therapy, or excision. Unfortunately, these… more
Company: Caudill Seed Co., Inc. Agency/Program/Year/Phase: USDA / SBIR / 2004 / 1
Abstract: Evidence indicates that the consumption of cole crop vegetables, like broccoli, leads to a reduced risk of certain cancers in humans. Broccoli seed and seedling sprouts contain high levels of the compounds glucoraphanin and its by-product sulforaphane, which is known to provide a protective effect… more
Company: CUSTOMKYNETICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 2
Abstract: DESCRIPTION (provided by applicant): We propose to develop an electrical stimulation system with adaptive capabilities for exercise and rehabilitation. The target populations are: 1) individuals with complete or incomplete SCI who are interested in improving their physical fitness through… more
Company: Microsensor Systems Inc. Agency/Program/Year/Phase: NASA / STTR / 2004 / 1
Abstract: This proposal describes the development of passive surface acoustic wave (SAW) sensors and multi-sensor systems for NASA application to remote wireless sensing of temperature and pressure distributions in space vehicles and demanding environments. SAW devices are a mature technology used in numerous… more
Company: NAPROGENIX, INC Agency/Program/Year/Phase: HHS / STTR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): Alcoholic liver damage (ALD) is among the ten most common causes of death in the USA. The liver may be uniquely sensitive because it metabolizes ethanol at a high rate. This generates acetaldehyde intracellularly, damaging cell components directly, and/or… more
Company: NetQuest Services, LLC Agency/Program/Year/Phase: USDA / SBIR / 2004 / 1
Abstract: The US cattle industry is subjected to two billion dollars in health care costs and losses annually. The majority of these losses relating to feedlots are a result of dense animal populations. Historically diagnosis of sick animals has been visual and by the time a sick animal is identified the… more
Company: OCULAR TRANSPLANTATION, LLC Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant) Retinal diseases such as macular degeneration, retinal dystrophies, and retinitis pigmentosa (RP) afflict more than 8.5 million Americans. As the population ages, this number will grow significantly, and many people will suffer from vision loss due to degeneration… more
Company: ORCCA TECHNOLOGY, INC. Agency/Program/Year/Phase: HHS / STTR / 2004 / 2
Abstract: DESCRIPTION (provided by applicant): This project will develop, evaluate and distribute an interactive multimedia program to provide interactive instruction about the human nervous system using a programmed learning format. The program will also provide extensive self-testing for the competencies to… more
Company: Paras Research Corporation Agency/Program/Year/Phase: DOE / SBIR / 2004 / 2
Abstract: 72094-Continued increases in the amount of carbon dioxide (CO2) in the atmosphere may eventually lead to global warming. Of the sequestration approaches that have been proposed, the secure sequestration of CO2 in the natural ecosystem appears to be a very efficient way to offset CO2 emissions… more
Company: Paras Research Corporation Agency/Program/Year/Phase: DOE / SBIR / 2004 / 1
Abstract: 75109-The sequestration of carbon dioxide (CO2) ¿ in used oil and gas fields, in coal beds for oil or methane recovery, in aquifers, in deep seas and sea bottoms ¿ requires that the CO2 be of relatively high purity. This presents a problem with the sequestration of CO2 from flue gas. In… more
Company: PARATECHS CORP. Agency/Program/Year/Phase: USDA / SBIR / 2004 / 1
Abstract: Insects are major pests of plant and animal food and fiber and also vector diseases causing millions of human deaths and untold suffering annually. Moreover, our efforts to control insect pests have caused massive environmental contamination and continue to cause many human and animal fatalities… more
Company: PEPTIDES INTERNATIONAL, INC. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 2
Abstract: DESCRIPTION (provided by applicant): Many widely used therapeutically important peptide drugs and hormones (annual international sales: $13 billion) are cyclized by means of disulfide bridges. However, the production of these peptides is difficult and expensive, due to formation of numerous… more
Company: PHOENIX PHARMACOLOGICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 2
Abstract: DESCRIPTION (provided by applicant): Unformulated human tumor necrosis factor( (huTNF() has anti-tumor activity in mice, but there is little difference between the effective and lethal doses. Systemic administration of unformulated huTNFalpha has been tested in humans. All studies indicated the… more
Company: PHOENIX PHARMACOLOGICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): Unformulated human tumor necrosis factor( (huTNF() has anti-tumor activity in mice, but there is little difference between the effective and lethal doses. Systemic administration of unformulated huTNFalpha has been tested in humans. All studies indicated the… more
Company: POTENTIA PHARMACEUTICALS, INC Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): The goal of this proposal is to develop a new, groundbreaking technology for the rapid identification of ligands for proteins. Every year, the pharmaceuticals industry loses about $3 billion by targeting genes/proteins wrongfully identified as the cause of… more
Company: POTENTIA PHARMACEUTICALS, INC Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): The goal of this proposal is to develop a new genetic system that will mimic the natural process of evolution for a selected subset of genes inside of a bacterial cell. Instead of an evolutionary time scale of years, evolution will proceed at an accelerated rate… more
Company: REGENEREX, LLC Agency/Program/Year/Phase: HHS / STTR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): Sickle Cell Disease (SCD) is an abnormality of red blood cells (RBC) that affects approximately 72,000 people in the United States, or approximately 1 in every 500 African-Americans. With current therapies, the mortality in the United States is 50 percent by age… more
Displaying 276 – 300 of 517 Awards
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