Abstract:DESCRIPTION (provided by applicant): There is a significant unmet medical need to provide additional pharmacologic treatments for treatment and prevention of opioid overdose. This Fast Track STTR project proposes to apply drug delivery technologies to develop a novel use for a nasally delivered… more
Abstract:In traditional GMAW and modifications, the current melting the wire is the same as the current heating the base metal. To maintain a minimally acceptable productivity, the base metal heat input is typically much greater than the required to control the distortion at an acceptable or desirable level.… more
Abstract:Research is proposed for the development and implementation of state of the art, reduced order nonlinear aeroelastic models for multidisciplinary/multi-fidelity optimization problems. Highly efficient and accurate aeroelastic simulation tools will be constructed based upon the mathematical formalism… more
Abstract:The proposed research program will develop a physics-based identification, modeling and risk management infrastructure for aeroelastic transonic flutter and limit-cycle oscillations (LCO). This capability will be built upon high fidelity state-of-the-art theoretical/computational methods as… more
Abstract:The proposed work aims at developing techniques that will address the current limitations of Cartesian-based Navier-Stokes CFD schemes by exploring three promising methods of implementing improved wall boundary conditions. The three methods are based on: (1) the diamond stencil approach of Delanaye… more
Abstract:This SBIR aims at developing a high-fidelity, yet efficient and easy-to-use, composite rotor blade and wing section design environment to facilitate rapid and confident aeromechanics assessment during conceptual design stages. A well-known technical barrier for composite rotor blade and wing section… more
Abstract:DESCRIPTION (provided by applicant): Currently buprenorphine (BUP) is used in the treatment of opioid abuse and for pain management. It can also be used improperly and abused as an opioid. In the United States, buprenorphine is marketed in sublingual and i
njectable forms. While the drug provides… more
Company:3 H CompanyAgency/Program/Year/Phase:NSF / SBIR / 2009 / 1
Abstract:This Small Business Innovation Research Phase I project is to demonstrate an innovative low cost, low energy-consuming, and novel CO2 capture technology based on a process entitled ?Split Amine Absorption?. The Phase I objective is to develop data necessary to confirm the principle of the concept… more
Company:3 H CompanyAgency/Program/Year/Phase:DOE / SBIR / 2009 / 1
Abstract:CO2 is one of the major components that cause global warming. Current technologies for CO2 separation are too expensive, especially with respect to CO2 capture from post combustion flue gas. This project will develop a low-cost viable process, Phase Transitional Absorption, to capture CO2 from… more
Abstract:Military network environments will be subject to both internal and external threats for the foreseeable future. Internal threats to cyber networks from U.S. personnel receive little attention in comparison to external threats; yet, the consequences can be even more devastating. The lack of tools… more
Abstract:This program is to develop multi-layered,light weight armor alloys systems that offer improved fragmentation and armor piercing performance as compared to any other monolithic structures. Such alloys and laminated configuration will be developed by utilizing advanced computational techniques to… more
Abstract:Two different approaches will be investigated for producing aluminum alloys with a layer structure that have mechanical properties similar to Al 7050-T7 and Al 7075-T6 and greatly improved corrosion resistance. Layered aluminum alloys will be produced using the Novelis-FusionT casting process. … more
Abstract:The objective of this program is develop high strength aluminum alloys ( as high strength as that of 7075-T6) that would not require anodization to achieve corrosion resistance. Among the Al alloy systems, only 7xxx and Al-Cu-Li alloy systems are capable of such a high strength level of 7075-T6… more
Abstract:DESCRIPTION (provided by applicant): Detection of ovarian cancer at Stage I results in 5-year survivals of greater than 90%; however, only 23% of ovarian cancers are diagnosed early, with 67% being diagnosed with metastatic disease. Thus, new markers are b
eing sought to accurate identify patients… more
Abstract:DESCRIPTION (provided by applicant): Periodontal disease has been recently identified as a risk factor for increased morbidity and mortality for systemic diseases such as pancreatic cancer, cardiovascular disease (atherosclerosis, myocardial infarction, a
nd stroke), and diabetes, as well as for… more
Abstract:DESCRIPTION (provided by applicant): Transcutaneous electrical stimulation applications involving high numbers of stimulated muscles have been an area of growing interest in recent years. customKYnetics has been approached in recent months by research gro
ups and stimulation application developers… more
Abstract:In this proposal, Global Quality Corp., in collaboration with researchers from University of Cincinnati and Wright State University, proposes to develop NetSafe -a systemwide simulation software for predictive simulation of the fate and transport of chemical and biological agents in DWDS. Based on… more
Abstract:This Small Business Innovation Research Phase I project is to develop and commercialize a powerful new diagnostic assay platform for quantitative analysis of plasma from human blood using Differential Scanning Calorimetry. The platform will form the basis for generating novel high-throughput… more
Abstract:DESCRIPTION (provided by applicant): NaugaNeedles LLC in collaboration with researchers from Purdue University are proposing to develop an advanced new Ultra-Soft Atomic Force Microscope (USAFM). This USAFM can gently create images of soft biological sampl
es in buffer solutions with sub-picoNewton… more
Abstract:Despite the importance of jet fighter afterburner designs, there exists very little data on the majority of the individual components of jet fuel, especially JP-8, to enable development of a detailed kinetic mechanism. Although the Multi University Research Initiative program has been initiated for… more
Abstract:Conventional plasma waste reforming technology uses high temperature reactive plasma to breakdown wastes into combustible gas and solid waste. Extremely high plasma temperatures often lead to high energy consumption resulting low efficiency and formation of unwanted byproducts, such as nitrogen… more
Abstract:This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Small Business Innovation Research(SBIR)Phase II project seeks to overcome the principal impediments of the inconsistent quality of metal matrix composite (MMC) materials from fly ash and aluminum… more
Abstract:DESCRIPTION (provided by applicant): The ability to genetically modify mice through methods of gene transfer in fertilized mouse embryos (transgenic mice) or gene modification in embryonic stem (ES) cells (gene targeting) has dramatically increased the va
lue and use of mice in biomedical research.… more
Abstract:DESCRIPTION (provided by applicant): Antibiotic resistant pathogenic microbes are responsible for thousands of human fatalities worldwide each year. The heightening risk of emerging pathogen resistance in clinical settings promotes the need for discovery a
nd development of new antibiotics with a… more
Abstract:DESCRIPTION (provided by applicant): SCR, Inc. (Louisville, KY) is developing a chronic implantable CPD system to treat HF patients who may be responsive to long-term counterpulsation support. The CPD has been developed for superficial implantation via a p
acemaker incision without the need to enter… more
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