Abstract:As aquaculture, particularly marine aquaculture continues to expand worldwide environmental regulations pertaining to waste discharge from fish farms are also becoming more stringent having an environmentally sound waste management, recovery and disposal plan are thus becoming increasingly more… more
Abstract:DESCRIPTION (provided by applicant): The principal goal of this research project will be to evaluate 4-demethyl-4- cholesteryloxycarbonylpenclomedine (DM-CHOC-PEN), a polychlorinated cholesterol carbonate as anticancer therapy for patients with advanced cancer in a Phase II clinical trial. During… more
Abstract:This project will identify a toolset which can be used by forward deployed Marines to assess structural damage to combat vehicles hulls following IED events. Improving the quality of Battle Damage Assessment in the field will reduce safety risk from vehicles returned to service without inspection,… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project concerns the design and high-throughput and low-cost manufacturing of metal-based miniature gas chromatograph (mGC) sensor structures. The proposed mGC sensor design and manufacturing is unique and offers competitive advantages as… more
Abstract:Mezzo Technologies fabricates high performance micro tube heat exchangers. In this proposal, Mezzo proposes to fabricate a heat exchanger to interface between helium, which is the working fluid used to cool a variety of superconducting components on Navy vessels in the future that will require… more
Abstract:The goal of this program is to develop compact, lightweight, low power thermal management systems for non-lethal weapons platforms, specifically the Radio Frequency Vehicle Stopper (RFVS) and the Active Denial Technology (ADT) system. In the Phase I effort, Mezzo designed thermal management systems… more
Abstract:This Small Business Innovation Research Phase II project proposes to develop and commercialize surface-engineered silicon anodes for use in lithium-ion batteries. Silicon has a ten fold greater charge capacity than graphite but its practical use as an anode material is hindered due to the mechanical… more
Abstract:Radio systems are easily subjected to unintentional or intentional interference that might disrupt normal communication. This program focuses on development of an anti-jamming system (AJS) that is backward compatible with the RT-1944/U radio and can be retrofit into the Multiple Vehicle… more
Abstract:This program will use a combination of hardware and software to remove narrow band interference from Satellite Communications (SATCOM) equipment. The system that will be developed in the phase II will act as a"black box,"which sits between the original SATCOM antenna system and SATCOM… more
Abstract:This Small Business Innovation Research Program (SBIR) Phase I project will develop leap-ahead improvement to public safety radio networks (PSRN). The problems associated with communication during a catastrophic event are well documented. One area of particular concern is the unreliability of PSRN.… more
Abstract:DESCRIPTION: We have preliminary data for a small molecule glyco-decoy that specifically side-tracks the biosynthesis of the ligand for E-selection, and is a candidate for a novel anti-inflammatory. The three members E, L and P of the selection family areinflammatory adhesion molecules expressed… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project proposes to develop a new technology for monitoring aggregation in therapeutic protein solutions that will have wide-ranging impact in the pharmaceutical and biotechnology industries. Protein aggregation is a major problem across these… more
Abstract:HydroFlame Technologies, LLC (HFT) is proposing to study the feasibility of combusting liquid fuels in the air core of rotating water for application in a downhole steam generator (DHSG). Deep reserves ( & gt;2500 ft) can be accessed by application of DHSGs. DHSGs increase the efficiency of… more
Abstract:There are approximately 7,000 flares in operation at industrial facilities across the U.S. Flares are one of the largest Volatile Organic Compounds (VOC) and air toxics emissions sources. Based on a special emission inventory required by the Texas Commission on Environmental Quality in 2007,… more
Abstract:ABSTRACT: The objective of this project is to develop nondestructive evaluation technology to locate and characterize defects and damage in ceramic matrix composite material with sufficient quantification to be usable in material performance models. The Evisive microwave interferometry technique… more
Abstract:Mezzo fabricates micro tube heat exchangers for a variety of applications, including aerospace, automotive racing, Department of Defense ground vehicles, economizers for ships, condensers, evaporators, liquid-liquid, liquid-air, recuperators, etc. Mezzo's expertise is designing, modeling and… more
Abstract:A next generation of Fan Coil Units (FCU) is proposed which utilize an intermediate temperature water supply at 68 F to meet HVAC heating and cooling loads on ships. These new next generation FCU will require active cooling (vapor compression cycles). Mezzo Technologies fabricates high performance… more
Abstract:ABSTRACT: This Phase II SBIR Project is aimed at development and successful demonstration of a working prototype of an active non-lethal infrasound avian denial system using infrasound energy based upon the Phase I results. The primary purpose of the system is to deny birds access to critical areas… more
Abstract:This Small Business Innovative Research (SBIR) Phase II project will further develop the next-generation DNA test kits for forensic DNA testing. DNA profiling has developed significantly over the past 20 years and is routinely used to solve crime. Despite improvements in DNA testing technologies and… more
Abstract:Through development of a combination of hardware and software, this program addresses the requirements of Satellite Communications (SATCOM) interference mitigation where no prior knowledge of the interference is available. The system will operate as a"black box,"which sits between the… more
Abstract:This Small Business Innovation Research Phase I project will demonstrate the feasibility of a novel meso-scale combustion based power generation system (MPGS). Meso-scale engines using liquid fuels have theoretical energy densities tens of times greater than the best battery technologies. The… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will employ an innovative approach to metabolically engineer algae and enable low-cost, carbon-free hydrogen production at medium to large scale. One approach to achieving high hydrogen production involves the use of green algae, which… more
Abstract:DESCRIPTION (provided by applicant): This Phase I SBIR, responding to RFA-AG-12-009 entitled T1 Translational Research on Aging from the NIA, explores novel cell-based therapeutic approaches to the treatment of pressure ulcers and full thickness skin wounds in the elderly. Although it is well… more
Abstract:DESCRIPTION (provided by applicant): The First Locally Acting Anti-Inflammatory Stem Cell-Based Therapy for Rheumatoid Arthritis Despite improved therapy; rheumatoid arthritis (RA) remains a significant unmet medical need. The long-term goal of this project is to advance the first stem cell-based… more
Abstract:DESCRIPTION (provided by applicant): CM101 is a polysaccharide tumor angiogenesis-targeting, complement activating, immune stimulating biological produced fermentatively from Group B Streptococcus. CM101 binds a capillary endothelium receptor, HP59, causing inflammatory cytokine cascades, recruiting… more
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