Abstract:This Small Business innovation Research (SBIR) Phase I research project aims to develop a web-based tool for the analysis of viral seqeunces. Availability of a sequence analysis tool that would help investigators manipulate viral sequences and detect contaminants would be of value to researchers as… more
Abstract:DESCRIPTION (provided by applicant): 7-butyl-10-aminocamptothecin (BACPT) and its water-soluble dipeptide pro-drug, are novel camptothecins that were designed to be used in the treatment of childhood neuroblastoma. These CPT analogs are lactones that have
increased activity in acidic hypoxia… more
Abstract:The objective of this proposal is to demonstrate the feasibility of the application of a patented microwave scanning device as an NDE technique to be used in streamlining and optimizing the Ceramic Matrix Composite (CMC) manufacturing process. The scanning process (U.S. Patent numbers 6,359,446 and… more
Abstract:The objective of this proposal is to demonstrate the feasibility of the application of a patented microwave scanning device as a portable NDE methodology to perform monitoring of the health of ceramic armor from non-projectile impacts. The scanning process utilizes microwaves as an interrogating… more
Abstract:"The goal of this project is to implement the industrial use of layer-by-layer
polyelectrolyte nanocoated pulp fibers, thereby to bring new technology to paper
making. The proposed work is based on our pioneering in the layer-by-layer
nanoassembly techniques and on our results on modification of… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project focuses on the implementation, testing, and refinement of a hybrid distributed / traditional system for broadcasting live and pre-recorded content to large online audiences at low cost. Traditional approaches to streaming media online… more
Abstract:This Small Business Innovation Research (SBIR) research project will develop a novel microcoil (or called microspring) sensing technology. Toxic proteins and bacterial pathogens pose a severe threat to the health of the general population and the military. The proof of concept experiments will be… more
Abstract:DESCRIPTION (provided by applicant): This Phase I program intends to develop an improved brachytherapy delivery system for treatment of lung cancer by incorporating radioactive 169Ytterbium sources into surgical staples used in lung resection. For patients
with compromised cardiopulmonary status,… more
Abstract:DESCRIPTION (provided by applicant): Intravenous drug administration is often clinically desired over oral administration, particularly for patients who have difficulty taking an oral drug due to their disease or condition (eg, unconsciousness, anesthetize
d). IV administration also produces a… more
Abstract:DESCRIPTION (provided by applicant): Chronically, medically resistant pain is one of the most significant health problems in our country and affects more than 50 million Americans. Neuropathic pain syndromes are for the most part resistant to traditional
analgesic treatments with NSAIDs,… more
Abstract:DESCRIPTION (provided by applicant): A key need for urea monitoring is a simple and disposable device that can be easily integrated with existing hemodialysis (HD) technology. This proposal aims to demonstrate the feasibility of accurate on-line urea clearance monitoring using nanoengineered… more
Abstract:DESCRIPTION (provided by applicant): Influenza virus is one of the most important human pathogens accounting for widespread morbidity and mortality. Influenza virus is currently classified as a NIAID Biodefense Category C priority pathogen, a status that may be upgraded due to the recent emergence… more
Abstract:DESCRIPTION (provided by applicant): 4-Hydroperoxyifosfamide (HOO-IFOS) is a stable, pre-activated form (peroxide) of 4-HO-IFOS, the initial metabolite of Ifosfamide (IFOS). Under physiological conditions HOO-IFOS under goes spontaneously ring opening and conversion to isophosphoramide mustard (IPM)… more
Abstract:Diamond Data Systems (DDS) proposes the development of a new advanced architecture, algorithms and software to support the end-to-end processing of LIDAR data to derive useful information products such as Digital Elevation Models (DEM). The approach is innovative in three ways. First, it proposes… more
Company:E & E ResearchAgency/Program/Year/Phase:USDA / SBIR / 2006 / 1
Abstract:The waste of unprocessed vegetable matter from normal harvesting can be used to create feeds for livestock and the pulp can be used to produce methanol for fuel. We feel that we should use all resources to their fullest potential. To create a refined machine that will allow the field processing of… more
Abstract:The goal of this project is to demonstrate a recuperator with extremely high effectiveness for use in a reverse turbo-Brayton (RTB) cryocooler. The recuperator will offer substantial system weight reduction, volume reduction, and performance increases for a cryocooler that can be used for Block 12… more
Abstract:The objective of this Phase II program is to develop and demonstrate a high performance heat exchanger technology for military ground vehicles such as the up-armored HMMWV. Mezzo will build a heat exchanger that is more compact, provides improved heat transfer performance, and meets the demands of… more
Abstract:The objective for this program is to increase the technical readiness level (TRL) of a Return Fuel Air Cooled (RFAC) heat exchanger (HX) based on Mezzo Technologies' proprietary microchannel technology to TRL 6 and an Oil/Fuel HX to a TRL 5. Mezzo will team with Lockheed Martin on this program. The… more
Abstract:Omni Technologies, Inc. (OTI) is proposing to develop an autonomous, geotechnical survey tool for mapping marine sediment properties. Our approach is to leverage one of the available man-portable autonomous underwater vehicles (AUVs) and develop an instrument capable of surveying a wide area. OTI… more
Abstract:Special Operations forces (SOF) operate in all weather conditions. It has identified a need for a micro-cooling system that can be vehicle mounted and man-portable, as well as provide a capability to cool vehicle mounted communications and electronics equipment. To meet the needs of SOF the system… more
Abstract:DESCRIPTION (provided by applicant): A particularly important national need exists for enhancing safety and security of environments ranging from residential structures, to subways, to airports, and to borders. Chemical warfare agents are 1 of the major th
reats to homeland security. Research that… more
Abstract:System Creations proposes to develop and manufacture radiation-hard nitride-based photovoltaics with photon to electric power conversion efficiencies of 40% or more at Atmospheric Mass 0 (AM0). The anticipated success of System Creation's approach is based on a novel nanofabrication technique,… more
Abstract:This SBIR project is aimed at development, design, prototyping, and demonstration of mobile ad hoc wireless networking (MAWNET) systems, energy efficient, reliable, low-latency and self-healing, networking amongst heterogeneous devices within the IP airborne network (IP-AN) using connectivity… more
Abstract:Combined animal feeding operations generate low value manure which cannot be economically transported more than a few miles and cannot be used locally at proper agronomic rates. Local nutrient overload then occurs, potentially resulting in odors, lowered water quality and pest insects; depending on… more
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