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Displaying 18701 – 18725 of 20354 Awards
Company: Biotechnica Diagnostics Inc Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: THE USE OF ANTIBIOTIC THERAPY FOR INFECTION MANAGEMENT HAS INCREASED DRAMATICALLY IN THE AREA OF PERIODONTAL DISEASE AS AN ADJUNCT TO SCALING AND SURGERY TREATMENT. WITH THE EMERGENCE OF ANTIBIOTIC USE IN PERIODONTAL DISEASE CARE, ALMOST NO WORK HAS BEEN DONE IN ASSESSING THE DEVELOPMENT OF… more
Company: Biotechnica Diagnostics Inc Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: THE ROLE OF EIKENELLA CORRODENS, FUSOBACTERIUM NUCLEATUM, AND WOLINELLA RECTA AS PATHOGENS ASSOCIATED IN DESTRUCTIVE PERIODONTAL DISEASE HAS BEEN DESCRIBED IN A NUMBER OF STUDIES USING CULTURE BASED ASSAY SYSTEMS. THE STANDARD CULTURE METHODS ARE INADEQUATE FOR THE ROUTINE DIAGNOSIS OF THESE… more
Company: BIOTEK, INC. Agency/Program/Year/Phase: DOD / SBIR / 1988 / 2
Abstract: COMBAT WOUNDS ARE CHARACTERIZED BY A HIGH INCIDENCE OF INFECTION. TOPICAL APPLICATION OF BROAD SPECTRUM ANTIMICROBIAL AGENTS BY SUSTAINED RELEASE SYSTEM CAN PROVIDE THERAPEUTIC LEVELS FOR A PROLONGED PERIOD WITH MINIMAL SYSTEMIC TOXICITY. BIOTEK IS DEVELOPING A WOUND DRESSING BASED ON THIS CONCEPT.… more
Company: BIOTEK, INC. Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: THE OVERALL OBJECTIVE OF THE PROJECT IS TO DEVELOP A TRANSDERMAL DOSAGE FORM OF THE H(1)-BLOCKER CARBINOXAMINE FOR 24-HOUR CONTROL OF ALLERGIC RHINITIS. IN PHASE I THE FEASIBILITY OF SUCH DOSAGE WILL BE TESTED. IN VITRO TRANSDERMAL PENETRATION EXPERIMENTS WITH NUDE MOUSE SKINS, AS WELL AS IN VIVO… more
Company: BIOTEK, INC. Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: N/A
Company: Boreas Inc. Agency/Program/Year/Phase: DOE / SBIR / 1988 / 1
Abstract: N/A
Company: BOSTON BIOTECHNOLOGY CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: THE LONG RANGE OBJECTIVE OF THIS RESEARCH IS TO REDUCE THE TOXICITY AND CARCINOGENICITY OF ASBESTOS BY DESFERROXAMINE TREATMENT, WHICH NEUTRALIZES THE CATALYTIC ACTIVITY OF THE ASBESTOS-CONTAINED IRON. IN PHASE I OF THIS PROJECT THE POSSIBILITY THAT DESFERROXAMINE TREATMENT CAN REDUCE… more
Company: Busek Co. Inc. Agency/Program/Year/Phase: DOE / SBIR / 1988 / 1
Abstract: N/A
Company: Cambridge Analytical Assoc Inc Agency/Program/Year/Phase: NSF / SBIR / 1988 / 1
Abstract: CHLORINATED SOLVENTS SUCH AS TETRACHLOROETHYLENE, HAVE BEEN SPILLED AND DISPOSED OF ON SOIL AND HAVE BEEN TRANSPORTED TO THE GROUND WATER, CAUSING WIDESPREAD AQUIFER CONTAMINATION. THESE COMPOUNDS ARE OF CONCERN BECAUSE OF THEIR TOXICITY AND SUSPECTED CARCINOGENICITY. CHLORINATED SOLVENTS HAVING… more
Company: Cambridge Biotech Corp.ora- Ti Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: N/A
Company: CAMBRIDGE NEUROSCIENCE Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: EXCITATORY AMINO ACIDS (EAAS) ARE IMPLICATED IN THE PATHOLOGY OF A NUMBER OF HUMAN NEUROLOGICAL DISORDERS, INCLUDING EPILEPSY, ISCHEMIC BRAIN DAMAGE, AND NEURODEGENERATIVE DISEASES SUCH AS HUNTINGTON'S DISEASE AND ALZHEIMER'S DISEASE. THE ROLE OF EAAS IN THESE DISORDERS APPEARS TO INVOLVE ABNORMALLY… more
Company: CAMBRIDGE NEUROSCIENCE Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: N/A
Company: CAMBRIDGE SCIENTIFIC, INC. Agency/Program/Year/Phase: USDA / SBIR / 1988 / 1
Abstract: N/A
Company: CAMBRIDGE SCIENTIFIC, INC. Agency/Program/Year/Phase: DOD / SBIR / 1988 / 1
Abstract: N/A
Company: CANDELA CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1988 / 2
Abstract: CARDIOVASCULAR DISEASE IS THE LEADING CAUSE OF DEATHS IN THEUNITED STATES, CLAIMING NEARLY TWICE AS MANY LIVES AS CANCER. LASER ANGIOPLASTY HAS IMMENSE APPEAL, BUT A RELIABLE, PREDICTABLE SYSTEM HAS NOT YET BEEN DEVELOPED. RESEARCHERS HAVE CONDUCTED PRELIMINARY STUDIES TO DEMONSTRA-TE PREFERENTIAL… more
Company: CANDELA CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: CANDELA LASER CORPORATION AND UCLA TISSUE TYPING LABORATORY PROPOSE TO DEVLOP A GROUP OF DYE TAGGED MONOCLONAL ANTIBODIES AND A LASER TO TARGET THESE DYES, FOR THE PEREFERENTIAL DESTRUCTION OF HUMAN T CELLS FROM A MIXTURE OFT AND B CELLS AND ALSO ACINAR CELLS IN THE PRESENT OF SLIT CELLS. THE… more
Company: CANDELA CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: N/A
Company: Cape Cod Research Agency/Program/Year/Phase: DOE / SBIR / 1988 / 1
Abstract: HIGH CRITICAL TEMPERATURE SUPERCONDUCTING CERAMICS HOLD PROMISE FOR NUMEROUS APPLICATIONS IN ENERGY STORAGE, COMMUNICATIONS AND SENSING TECHNOLOGIES. HOWEVER, TECHNICALPROBLEMS ASSOCIATED WITH THE FABRICATION AND PROCESSING OF THESE MATERIALS MUST FIRST BE OVERCOME. THIS RESEARCH PROJECT APPLIES… more
Company: Cape Cod Research Agency/Program/Year/Phase: DOD / SBIR / 1988 / 1
Abstract: SUPERCONDUCTING CERAMICS HOLD PROMISE FOR NUMEROUS APPLICATIONS IN ENERGY STORAGE, COMMUNICATIONS AND SENSING TECHNOLOGIES. HOWEVER, TECHNICAL PROBLEMS ASSOCIATED WITH THE FABRICATION AND PROCESSING OF THESE MATERIALS MUST FIRST BE OVERCOME. THIS RESEARCH APPLIED ELECTROCHEMICAL DEPOSITION TO THE… more
Company: Cape Cod Research Agency/Program/Year/Phase: DOD / SBIR / 1988 / 1
Abstract: THE BATTERY SYSTEMS PRESENTLY USED TO POWER NAVAL MINES HAVE VERY LIMITED SHELF LIVES AND VERY LIMITED SPECIFIC POWER AND SPECIFIC ENERGY. THEY LIMIT THE LONG-TERM PERFORMANCE OF SOPHISTICATED SYSTEMS FOR DETECTION OF TARGETS AND CONTROL OF THE MINE. THIS RESEARCH INVESTIGATES THE FEASIBILITY OF… more
Company: Cape Cod Research Agency/Program/Year/Phase: DOD / SBIR / 1988 / 1
Abstract: THIS RESEARCH INVOLVES THE DEVELOPMENT OF A NOVEL TYPE OF CHEMICAL AGENT RESISTANT COATING (CARC) FOR AVIATION GROUND SUPPORT SYSTEMS. THE APPROACH IS TO EXTEND THE CAPABILITIES OF STATE-OF-THE-ART PAINTS BY INCORPORATING AN ADDITIONAL COMPONENT WHICH WILL CHEMICALLY NEUTRALIZE THE TOXIC EFFECTS OF… more
Company: Cape Cod Research Agency/Program/Year/Phase: DOD / SBIR / 1988 / 1
Abstract: A PROCESS FOR PREPARING ALUMINUM ALLOYS FOR ADHESIVE BONDING IS PROPOSED WHICH CAN SIGNIFICANTLY SIMPLIFY ADHESIVE BONDED REPAIR IN THE FIELD. THE PROPOSED RESEARCH EXPLORES THE FEASIBILITY OF USING NON-HAZARDOUS SURFACE TREATMENTS ON ALUMINUM ALLOYS WHICH PROVIDE ADHESIVE BONDS WITH EQUAL OR… more
Company: Cape Cod Research Agency/Program/Year/Phase: DOD / SBIR / 1988 / 1
Abstract: REMOTE DETECTION OF MINUTE CONCENTRATIONS OF AROMATIC HYDROCARBONS IN GROUNDWATER USING STATE-OF-THE ART ANALYTICAL EQUIPMENT IS VERY DIFFICULT. ADDING THE CONSTRAINT OF MAKING THE MEASUREMENTS IN REAL-TIME, AND THE TASK BECOMES IMPOSSIBLE. THIS RESEARCH EXPLORES THE FEASIBILITY OF DEVELOPING A NEW… more
Company: Cape Cod Research Agency/Program/Year/Phase: NSF / SBIR / 1988 / 1
Abstract: N/A
Displaying 18701 – 18725 of 20354 Awards
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