Abstract:The DoD is replacing its legacy tactical satellite communications (SATCOM) system known as the UHF Follow-On (UFO) system with its next generation Mobile User Objective System (MUOS) as UFO reaches the end of its useful life. The MUOS SATCOM system will enable warfighters to communicate directly… more
Abstract:ABSTRACT: MIL-HDBK-1530C to dictate how to maintain USAF aircraft through the Aircraft Structural Integrity Program (ASIP), which uses damage tolerant analysis (DTA) to set inspection intervals. While effective and safe, DTA can also be quite conservative, leading to excessive down-time for depot… more
Abstract:The proposed innovation is a power conversion technology that will help achieve NASA's Fundamental Aeronautics Program (FAP) goals of reducing emissions and increasing fuel efficiency for high speed flight. NASA's objective to increase the specific power of high efficiency electric… more
Abstract:Space structures are unique in that once they are deployed, there is little to no opportunity for manual inspection to assess their integrity. Even on the space station, where there is a continuous human presence, traditional non-destructive evaluation (NDE) is impractical due to complexity of… more
Abstract:DESCRIPTION (provided by applicant): Human cytomegalovirus (HCMV) infection is a major cause of morbidity and mortality in immunosuppressed patients, especially recipients of solid organ or bone marrow transplants. HCMV infection of neonates is associatedwith deafness, mental retardation, and… more
Abstract:DESCRIPTION (provided by applicant): Because of the emergence of resistance to known antibiotics, there is a critical need for new antibacterial agents, especially against Gram-negative pathogens. trans-Translation is a biochemical pathway that is essential to many bacterial species, including… more
Abstract:DESCRIPTION (provided by applicant): Lassa fever virus (LASV) and Machupo virus (MACV) are hemorrhagic fever arenaviruses which are classified as Category A Agents. Currently, there are no licensed LASV or MACV vaccines and LASV/MACV therapy is limited touse of the nucleoside analog ribavirin, which… more
Abstract:DESCRIPTION (provided by applicant): Ebola and Marburg viruses belong to the family Filoviridae and can cause fatal hemorrhagic fevers characterized by widespread tissue destruction with an incubation period of 4-14 days. Because of the safety concerns, these viruses are designated as the biosafety… more
Abstract:DESCRIPTION (provided by applicant): The overall objective of this project is to develop a novel chemical class of tuberculosis (TB) therapeutic agents, the spectinamide series, for use against MDR and XDR strains of Mycobacterium tuberculosis (Mtb) and identify, through a series of in vivo efficacy… more
Abstract:In order to meet national energy goals, DOE has set aggressive R & amp;D targets for advanced manufacturing technology to produce high efficiency organic LED (OLED) solid-state lighting (SSL) products. Achieving these goals will result in significant energy savings, cost reductions, and… more
Abstract:The overall goal of the SBIR program is to develop a new Application Specified Integrated Circuit (ASIC) driver to be used in driver electronics of a deformable mirror (DM) system in order to reduce power dissipation, improve controllability, enhance preciseness, and to significantly reduce the form… more
Abstract:ABSTRACT: In military aircraft tires, the wheel-tire interface (bead-seat) region is of particular interest since the generated ground forces terminate into the load-bearing"bead-seat"contact area. Thus, the forces generated in both the tire and wheel interface region is of interest.… more
Abstract:Military engine performance can be optimized for power and efficiency despite variable fuel properties if combustion chamber pressure can be measured in real-time. Unfortunately, IC engine pressure sensors are mostly confined to research applications due to their cost. A commercial off-the-shelf… more
Abstract:Transition from schedule-based to condition-based maintenance (CBM) of submarine equipment would significantly reduce operating costs and extend system lifetime by eliminating unnecessary maintenance activities. Key challenges to implementing autonomous health monitoring for submarine components are… more
Abstract:Mide has developed a long duration zero power sensing technology. The technology has been designed to allow a system to continuously monitor itself when removed from hardwired power for several years. Mide has designed, built and tested prototypes in relevant environments. Mide proposes to use… more
Abstract:The Navy is seeking a new light-weight Atmospheric Diving Suit (ADS) design. This suit must be less than 400 lbs; at this weight a diver will be able to self-propel using his legs and fins. The system must ensure the divers safety at a working depth of 1000 ft of sea-water; protecting the body from… more
Abstract:ABSTRACT: NanoLab proposes to develop a non-contact data transfer device to replace slip-rings in rotating assemblies. The proposed device will offer up to 300 channels of secure data delivery across the rotating frame at speeds of 20khz or higher. Further this device will be able to handle… more
Abstract:DESCRIPTION: With the recent discovery of 5-hydroxymethylcytosine in mammalian DNA and the TET enzyme family responsible for its generation, it is clear that the mammalian DNA epigenome is much more complex than had been thought. A lot of questions remainto be answered about the in vivo roles and… more
Abstract:PROJECT SUMMARY/ABSTRACT Type 1 diabetes (T1DM) is the most common chronic illness in children, affecting 1 in 400 with evidence that its prevalence is increasing worldwide. Parents of children with T1DM are responsible for a labor-intensive and complicated daily regimen that has been described as… more
Abstract:The project is developing a new sensor technology that can measure carbon dioxide levels with precision that matches or exceeds the state-of-the-art performance, but will reduce the price dramatically, and will for the first time enable instruments deployed in remote locations to operate unattended… more
Abstract:NOVA Scientific proposes the development of efficient position sensitive detectors capable of time-tagging epithermal energy neutrons with high accuracy and efficiency. These devices will be able to perform energy-resolved imaging at the pulsed neutron sources and detect every neutron with spatial… more
Abstract:The overall goal of this project is to develop a selective antibiotic against Clostridium difficile, the major agent responsible for antibiotic-induced diarrhea and colitis. The pathogen can be carried in healthy individuals, and is kept at bay by gut symbionts. Antibiotic treatment suppresses the… more
Abstract:Drifting mines pose a serious threat to the safe passage of US and international naval and commercial shipping traffic. In this SBIR, OASIS Inc. proposes to combine two algorithms developed under ONR/SPAWAR funding into a Mine Drift Tactical Decision Aid (MD-TDA). These algorithms include a tracer… more
Abstract:In this STTR, OASIS Inc, with partners the Massachusetts Institute of Technology (MIT) and the Applied Physics Laboratory University of Washington (APL-UW) proposes to develop an innovative, interactive submarine acoustic counter detect TDA for use by the Submarine Mission Planners, within the… more
Abstract:The proposed work will address the core physics underlying acoustic reverberation as related to properties of the ocean environment and properties of the acoustic sources, receivers and waveforms that make up ocean-going acoustic systems of interest to the U.S. Navy. Present day active acoustic… more
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