Abstract:DESCRIPTION (provided by applicant): In this study, we propose a Non-Destructive Molecular Extraction (NDME) platform to perform quantitative proteomics analysis of FFPE specimens with SILAC cell dot controls. The NDME technique can directly extract proteins from a single fixed tissue section… more
Abstract:DESCRIPTION (provided by applicant): Over the past decade, the number of people living with HIV has increased while the annual number of new infections has remained relatively stable. Gay, bisexual, and other men who have sex with men (MSM), particularly young black/African American MSM (YBMSM), are… more
Abstract:NOAA has identified a problem with the display and usability of satellite imagery on NWS websites. This proposal provides analysis of the feasibility and usability of a proposed system to address this concern. Our goal in the project is to create a heuristically sound conceptual design and tool… more
Abstract:DESCRIPTION (provided by applicant): Recent advances in countercurrent chromatography (CCC) have created novel spiral-design separation columns that hold a very high stationary phase of all the solvent systems, such that now all molecules of any size and water solubility can be successfully… more
Abstract:Chesapeake Technology International"s (CTI"s) proposed solution for the Tripwires for PEO C4I Systems is the development of a system of active and passive monitors that will provide status on PMW-120 systems with no modification to existing equipment or installations. While a number of… more
Abstract:Chesapeake Technology International"s proposed solution for the"Intelligent Multi-Computing-Platform for Complex Tactical Manned and Unmanned Engagement Planning and Data Distribution"SBIR program is the Synchronized Collaborative Open Planning Environment, or SCOPE. SCOPE builds upon… more
Abstract:ABSTRACT: Identifying the presence of endangered and threatened species is crucial to complying with Environmental Protection Agency regulations. Each year military reservations spend large amounts of resources in time, materials, and manpower in identifying if endangered or threatened species are… more
Abstract:The proposed research will lead to a hybrid laser communications and ultra wide band (UWB) radio frequency communication system that will provide the maximum throughput achievable (>>1Gb/s) with novel emerging state-of-the-art technology, while also providing graceful degradtion should laser… more
Abstract:ABSTRACT: The ability of plasmas to modify combustion has been known for more than 50 years. Recent advances in plasma generation technology and measurement diagnostics have led to extensive efforts to understand both the kinetics of the plasma-flame interaction and the enhancement of combustion… more
Abstract:ABSTRACT: Ramjets and scramjets are the preferred propulsion platforms for flight in the supersonic (3<M<5) and hypersonic (5<M<15) regimes, respectively. Combustion phenomena in ramjets and scramjets are highly unsteady and susceptible to compressibility effects. Also, this flow can… more
Abstract:ABSTRACT: In recent years, diversification of energy dependence on foreign oil has attracted the use of alternative fuels such as the Fischer-Tropsch jet fuels and hydro-treated renewable jet fuels. However, there are combustion stability issues with alternative fuels in the aircraft engines… more
Abstract:Pyrotechnics offer a novel low energy Control Actuation System (CAS) approach reducing limitations associated with typical electro-mechanical CAS. With 2.5 to 3 times more usable energy stored per unit volume and more importantly a power density that is orders of magnitude greater than that of a… more
Abstract:The work to be conducted under this proposed effort will include design, analysis, and manufacture of composite sabot/pusher assemblies for US Navy specified sub-caliber gun launched HVP flight configurations. The overall scope of work will be divided into a Base, Option 1, and Option 2 efforts… more
Abstract:Metal-Organic Chemical Vapor Deposition (MOCVD) epitaxial processes are used to deposit the GaN, InGaN, AlGaN and other wide band-gap semiconductor thin films making up the buffer, quantum well, and cap layers of the next generation high- brightness LEDs (HB-LEDs) for… more
Abstract:ABSTRACT: The U.S. Air Force is tasked with detecting, tracking, identifying, characterizing, and cataloguing RSOs. This is currently done using a disparate network of sensors that are shared with other missions. The increasing number of objects and scarcity of sensors makes the task of identifying… more
Abstract:In the near future we will see the development of space mission architectures where multiple spacecraft work cooperatively as a cluster to achieve mission objectives. Fault management (FM) is a critical challenge that must be addressed, especially when multiple spacecraft are working in proximity. … more
Abstract:ABSTRACT: The goal of this Air Force Commercialization Readiness (CRP) effort is to transition the ultrasensitive laser-warning receiver (USLWR), developed during a previous SBIR project, and further matured in a RIF program, to Northrop Grumman"s Advanced Threat Warner (ATW). The objective is… more
Abstract:Heron Systems proposes Solar Prediction via Deep Learning (SPINDLE), a human out-of-the-loop system to improve the state of solar flare forecasting using novel machine learning techniques. Currently, solar flare forecasting is either dependent on an expert, with their own subjective biases and… more
Abstract:Interlinked Software for Achieving Analogous Control (ISAAC) offers capability to link geographically disparate N-DOF test beds to facilitate real-time distributed operations. ISAAC is an evolution of an existing distributed simulation architecture used extensively by the US Navy in multiple… more
Abstract:This SBIR Phase I project proposes to produce online software that enables deaf users to obtain English equivalents for American Sign Language (ASL) science, technology, engineering, and mathematics (STEM) signs. Many deaf and hard of hearing people who rely on ASL for communication do not have good… more
Abstract:DESCRIPTION (provided by applicant): The overall objective of the proposed research is to fully develop and conduct clinical translation of a novel technology that provides minimally invasive surgeons an ability to visualize exposed organ surfaces as wellas structures hidden by them, together with a… more
Abstract:Strawberries are the 2nd largest non-citrus fruit crop in the U.S., trailing grapes and surpassing apples (USDA 2012). With strawberries harvested for processing (as a value-added food ingredient), the calyx (the stem cap with green crown leaves) must be removed to avoid having inedible leaves in… more
Abstract:ABSTRACT: Minimally operating or non-operating systems provide little or no opportunity for measuring functional parameters as they degrade, reducing visibility into the condition of system reliability. The negative effects of this phenomenon are seen to a greater degree in systems that are… more
Abstract:DESCRIPTION (provided by applicant): Staphylococcus aureus is a Gram-positive human pathogen that causes a wide range of infections from skin and soft tissue infections (SSTI) to life threatening sepsis and pneumonia. The pathogenicity of S. aureus is dependent on numerous virulence factors,… more
Abstract:ABSTRACT: Intelligent Automation, Inc. proposes a game-theoretic framework for the design and analysis of a robust decision making tool for wideband satellite communications that integrates hierarchical spectrum sharing, spectrum sensing, waveform adaptation and active anti-jamming. We capture… more
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