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Displaying 6601 – 6625 of 7718 Awards
Company: LNK CORP., INC. Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: LNK Corp proposes to design a low-cost, domain-independent, knowledge-based, tabletop Intellident Tutoring System (ITS) tool that will enable rapid prototyping and deployment of domain-specific ITS applications. This design will include a Teacher Module thqt can dynamically adapt its teaching… more
Company: LARGE SCALE BIOLOGY CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: THIS PROJECT RELATES TO THE INVENTION OF A SYSTEM FOR AUTOMATIC MULTIPLE-PARALLEL SYNTHESIS OR SEQUENCING OF BIOLOGICALLY IMPORTANT POLYMERS. CHEMICALLY SYNTHESIZED PEPTIDES, EACH OF WHICH STARTS AT A MORE ADVANCED POSITION ALONG PREVIOUSLY SEQUENCED CODING DNA (I.E., WALK ALONG THE GENE) ARE NOW… more
Company: LARGE SCALE BIOLOGY CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: THE HUMAN GENOME PROJECT REQUIRES THE RAPID SYNTHESIS OF VERY LARGE NUMBERS OF OLIGONUCLEOTIDE PRIMERS FOR POLYMERASE CHAIN REACTION (PCR) AMPLIFICATION OF HUMAN DNA, AND FOR USE AS PROBES FOR SEQUENCE-TAGGED SITES. THIS GRANT SEEKS TO INVENT A SYSTEM FOR THE RAPID AUTOMATIC MULTIPLE-PARALLEL… more
Company: Loats Associates, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: N/A
Company: Macro Systems, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: THE OBJECTIVE IS TO DEVELOP AN INNOVATIVE SOFTWARE PRODUCT BUILDING ON THE BEST AVAILABLE KNOWLEDGE OF COMPUTER ASSISTED TELEPHONE INTERVIEW CAPABILITIES. SPECIFIC AIMS OF PHASE I TO (1) INVESTIGATE THE NEEDS OF RESEARCH PROFESSIONALS REGARDING CATI SOFTWARE; (2) DEVELOP A PRELIMINARY CONCEPTUAL… more
Company: Macro Systems, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: N/A
Company: Macro Systems, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: N/A
Company: Manufacturing And Technology Conversion Int'l, Inc Agency/Program/Year/Phase: DOE / SBIR / 1991 / 2
Abstract: MTCI'S ALTERNATIVE SECOND-GENERATION ADVANCED PFBC CONCEPT EMPLOYS A PULSE COMBUSTION-BASED COMBUSTOR ISLAND IN THE TOPPING CYCLE. THE PULSE COMBUSTOR ACTS AS A VITIATED AIR BURNER AND SERVES TO INCREASE THE FLUE GAS TEMPERATURE FROM ABOUT 1600 DEGREES FAHRENHEIT AT THE EXIT OF THE PFBC TO ABOUT… more
Company: Manufacturing And Technology Conversion Int'l, Inc Agency/Program/Year/Phase: DOE / SBIR / 1991 / 1
Abstract: SYNCRUDE OIL OBTAINED BY RETORTING OIL SHALE REPRESENTS A POTENTIAL SOURCE OF FUEL AND CHEMICAL FEEDSTOCK. THE EXTENT OF TOTAL U.S. RESOURCES GREATER THAN 15 GALLONS OF SYNCRUDE OIL PER TON OF OIL SHALE IS ESTIMATED TO BE 2.5 TRILLION BBL. THE STATE-OF-THE-ART OIL SHALE RETORTING TECHNOLOGY IS NOT… more
Company: MARTEK BIOSCIENCE CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: THE (14)C-TRIOLEIN BREATH TEST IS A POPLAR ALTERNATIVE TO THE CLASSICAL 72-HOUR FECAL FAT COLLECTION FOR MEASURING FAT MALABSORPTION BECAUSE OF ITS SIMPLICITY AND THE RAPIDITY WITH WHICH A DIAGNOSIS CAN BE MADE. HOWEVER, BECAUSE OF THE CONCERN FOR THE LONG-TERM EFFECTS OF LOW-LEVEL RADIATION… more
Company: MARTEK BIOSCIENCE CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: DOCOSAHEXAENOIC ACID (DHA) IS THE MOST ABUNDANT LONG-CHAIN POLYUNSATURATED FATTY ACID IN THE GREY MATTER OF THE BRAIN. HUMANS CAN CONVERT DIETARY LINOLENIC ACID INTO DHA, BUT THIS PROCESS IS SLOW. CONSEQUENTLY, AT THE TIME OF THE MOSTRAPID BRAIN DEVELOPMENT IN THE FIRST FEW MONTHS OF LIFE, THERE IS… more
Company: MARTEK BIOSCIENCE CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: DEUTERATED OR 13-CARBON-LABELED L-LACTATE IS WIDELY USED IN MEDICAL DIAGNOSIS AND CLINICAL RESEARCH. THE STABLE, ISOTOPICALLY LABELED LACTATE IS NONTOXIC, AND NO ETHICAL OR DISPOSAL PROBLEMS DETER ITS USE IN HUMAN SUBJECTS. BY VIRTUE OF THEIR ABILITY TO GROW IN D2O INSTEAD OF H2O AND TOUSE (13)CO2… more
Company: MARTEK BIOSCIENCE CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: THE PRESENCE OF ENRICHED STABLE ISOTOPE CONTENTS IN PROTEINS, COUPLED WITH SOPHISTICATED TWO- AND THREE-DIMENSIONAL NUCLEAR MAGNETIC RESONANCE TECHNIQUES, ENABLES A RAPID AND EASY DETERMINATION OF AMINO ACID SEQUENCE AND PROTEIN STRUCTURE. GLYCEROL IS OFTEN USED AS THE SOLE CARBON SOURCE FOR THE… more
Company: MARTEK BIOSCIENCE CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: THE OVERALL GOAL OF THIS PROJECT IS TO MANUFACTURE AN OIL DERIVED FROM ALGAE WHICH IS ENRICHED IN OMEGA-3 POLYUNSATURATED FATTY ACIDS. PRELIMINARY DATA HAVE SHOWN THERE IS A DIATOM WHICH PRODUCES A NON-MEMBRANE ASSOCIATED TRIGLYCERIDE WITH A HIGH CONTENT OF EPA BUT LOW CONTENTS OF OTHER… more
Company: MARTEK BIOSCIENCE CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: BETA-CAROTENE (PROVITAMIN A) HAS RECENTLY BEEN SHOWN TO BE AN EFFECTIVE CHEMOTHERAPEUTIC AGENT IN THE TREATMENT AND PREVENTION OF CANCER. MOREOVER, CAROTENES PRODUCED BIOSYNTHETICALLY (CONTAINING 9-CIS ISOMERS) APPEAR TO BE A MORE EFFECTIVE ANTITUMOR AGENTS THAN THOSE PRESENTLY MANUFACTURED… more
Company: MARTEK BIOSCIENCE CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: N/A
Company: MCCREARY RESEARCH, INC. Agency/Program/Year/Phase: DOC / SBIR / 1991 / 1
Abstract: THE DISSEMINATION OF TIMELY WEATHER DATA IS BECOMING INCREASINGLY IMPORTANT AS THE POPULATION DENSITY OF THE UNITED STATES INCREASES. AS THE SOLE GOVERNMENT OPERATED RADIO SYSTEM PROVIDING DIRECT WARNINGS TO PRIVATE HOMES, THENOAA WEATHER RADIO (NWR) SYSTEM IS CRITICAL FOR DISSEMINATING NATURAL… more
Company: MEDIMMUNE, INC. Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: NUMEROUS EXPRESSION SYSTEMS EXIST FOR THE PRODUCTION OF PROTEINS IN BOTH PROKARYOTIC AND EUKARYOTIC CELLS. EACH SYSTEM HAS ITS OWN SET OF ADVANTAGES AS WELL AS SHORTCOMINGS. THE NEED REMAINS FOR A MAMMALIAN CELL EXPRESSION SYSTEM THAT CAN ACHIEVE HIGH-LEVEL TARGET GENE EXPRESSION, CORRECTLY PROCESS… more
Company: Mentor Technologies, Inc. Agency/Program/Year/Phase: DOC / SBIR / 1991 / 1
Abstract: THREE ASPECTS OF CLIMATE CHANGE INVOLVING VERY HIGH TROPICAL CLOUDS ARE: (1) WHETHER CHANGES IN HIGH CLOUD PARAMETERS LEAD TO POSITIVE OR NEGATIVE FEEDBACK IN CO2 EFFECTS ON CLIMATIC TEMPERATURE CHANGES; (2) DO CHANGES IN THE HEIGHTS OF CLOUD TOPS AND CLOUD AMOUNT, OR CLOUDS WHICH REACH TO THE… more
Company: Mentor Technologies, Inc. Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: THE OBJECTIVE IS TO DEVELOP A REMOTE VIDEO SENSOR UNIT WHICH WILL BE USED WITH A TRACKING SYSTEM. MTI HAS ALREADY DESIGNED AND HAS CONSTRUCTED A VIDEO SURVEILLANCE UNIT PROTOTYPE FOR A COMPETELY AUTOMATED MULTIPLE TARGET/MULTIPLE SENSOR TRACKING SYSTEM, UNDER CONTRACT TO THE U.S. ARMY, WHITE SANDS… more
Company: Mentor Technologies, Inc. Agency/Program/Year/Phase: DOD / SBIR / 1991 / 1
Abstract: VLSI (VERY LARGE SCALE INTEGRATION) TECHNOLOGY HAS BEEN DEVELOPED TO THE POINT WHERE SPECIAL PURPOSE PROCESSORS MAY BE CONCATENATED TO FORM COMPACT SUPERCOMPUTERS WITH FAR GREATER THROUGHPUT RATES THAN UNI-PROCESSOR MACHINES. THESE NEW MASSIVELY PARALLEL COMPUTERS PROMISE TO SOLVE THE ARMY'S EVER… more
Company: Micro-marketing Systems Inc Agency/Program/Year/Phase: HHS / SBIR / 1991 / 1
Abstract: THE PREVENTION OF DECUBITUS ULCERS (DU) REQUIRES CARE BY AIDES WHO MAY LIMITED KNOWLEDGE OR EXPERIENCE WITH THE CONDITION THEY ARE SEEKING TO PREVENT. HELPSKIN IS AN INFORMATION RESOURCE/DIRECTORY DESIGNED TO INCREASE NURSING CAREGIVERS KNOWLEDGE OF THE PREVENTION OF DU. IT IS DESIGNED FOR LOCATION… more
Company: Molecular Oncology Inc Agency/Program/Year/Phase: DOD / SBIR / 1991 / 2
Abstract: USE OF SYNTHETIC PEPTIDES, COMPRISING BOTH B AND T CELL DETERMINANTS, IS BEING CONSIDERED A VIABLE APPROACH TO VACCINE DEVELOPMENT. WE WILL EXPLORE THE SUITABILITY OF THIS STRATEGY EMPLOYING RIFT VALLEY FEVER VIRUS (RVFV) AS THE STUDY MODEL. THE IMMUNOGENICITY OF SYNTHETIC PEPTIDES REPRESENTING… more
Company: Molecular Oncology Inc Agency/Program/Year/Phase: HHS / SBIR / 1991 / 2
Abstract: FOR MANY TYPES OF CANCER, PATIENT MORBIDITY-AND ULTIMATELY MORTALITY-IS DUE TO THE DEVELOPMENT OF METASTATIC LESIONS. EXPERIMENTAL EVIDENCE SUGGESTS THAT TUMORS CAN INHERENTLY DIFFER IN THEIR ABILITY TO FORM METASTASIS. AS YET THERE ISNO AVAILABLE TEST TO DETERMINE IF PARTICULAR HUMAN TUMORS ARE OF… more
Displaying 6601 – 6625 of 7718 Awards
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