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State:Maryland
Company: SERACARE LIFE SCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 1987 / 1
Abstract: A NOVEL HUMAN B-LYMPHOTROPIC VIRUS (HBLV) HAS BEEN RECENTLY ISOLATED FROM PATIENTS WITH LYMPHOPROLIFERATIVE DISORDERS. THIS HERPES VIRUS HAS BEEN SHOWN TO INFECT B AND T LYMPHOCYTES AND TO ALTER THEIR MORPHOLOGY AND GROWTH CHARACTERISTICS. THE SIGNIFICANCE OF THE VIRUS IN CAUSING HUMAN DISEASES HAS… more
Company: Biosys Agency/Program/Year/Phase: USDA / SBIR / 1987 / 2
Abstract: INFECTIVE JUVENILES (IJ'S) OF STEINERNEMATID NEMATODES IN THE GENUS NEOAPLECTANA ARE EFFECTIVE CONTROL AGENTS FOR A WIDE RANGE OF INSECT PESTS. MARKET REQUIREMENTS FOR THE YEAR 1987 DETERMINE A PRODUCTION GOAL OF 1011 NEMATODES PER WEEK, WITH 1988 REQUIREMENTS APPROXIMATING 1016 PER WEEK. PHASE I… more
Company: Biotech Research Laboratory Agency/Program/Year/Phase: HHS / SBIR / 1987 / 2
Abstract: THE OVERALL OBJECTIVE OF THIS PROGRAM IS TO DEVELOP COST-EFFECTIVE TECHNOLOGY FOR THE SCALE-UP OF MAMMALIAN CELL CULTURE FOR THE MANUFACTURE OF PRODUCTS SUCH AS MONOCLONAL ANTIBODIES OR GENETICALLY ENGINEERED PROTEINS. THE APPROACH INVOLVES GROWTH OF CELLS IN THE INTERSTICES OF A POROUS MATRIX,… more
Company: Brimrose Corporation of America Agency/Program/Year/Phase: DOD / SBIR / 1987 / 2
Abstract: NUMEROUS STUDIES CONDUCTED IN THE PAST HAVE CLEARLY ESTABLISHED THE STRONG CORRELATION BETWEEN THE MICROSTRUCTURE AND THE ENERGETIC PROPERTIES OF SOLID PROPELLANTS SUCH AS RDX,HMX, AL, NH(4)CL0(4), ETC. THE PRESENT STUDY WILL EXAMINE THE FEASIBILITY OF USING A NONCONTACT, NON-DESTRUCTIVE X-RAY… more
Company: Brimrose Corporation of America Agency/Program/Year/Phase: NASA / SBIR / 1987 / 1
Abstract: A RECENT BREAKTHROUGH IN FATIGUE FAILURE PREDICTION HAS BEEN DEMONSTRATED BY A METHOD KNOWN AS DARC (DIGITAL AUTOMATED ROCKING CURVE) DIFFRACTOMETRY. THIS METHOD IS A NON-DESTRUCTIVE X-RAY PROCEDURE WHICH MEASURES DIRECTLY THE ACCRUED MICROSTRUCTURAL DAMAGE, THUS PERMITTING AN ASSESSMENT OF THE… more
Company: Brimrose Corporation of America Agency/Program/Year/Phase: DOD / SBIR / 1987 / 1
Abstract: II-VI SEMICONDUCTORS BASED INFRARED DEVICE TECHNOLOGY IS BECOMING INCREASINGLY IMPORTANT FOR MILITARY APPLICATIONS, ESPECIALLY IN RANGES OF 3-5 MICROMETERS AND 8-14 MICROMETERS WHICH CORRESPOND TO ATMOSPHERIC WINDOWS. IT HAS BEEN CONCLUSIVELY ESTABLISHED THAT PERFORMANCE OF THESE DEVICES DEPENDS… more
Company: Brimrose Corporation of America Agency/Program/Year/Phase: DOD / SBIR / 1987 / 1
Abstract: THE OBJECTIVE OF THIS PROGRAM IS TO FABRICATE AN INLINE FIBER-OPTIC MODULATOR. WITH OUR EXPERIENCE IN BUILDING ACOUSTO-OPTIC DEVICES WE HAVE DEVELOPED A UNIQUE BONDING TECHNIQUE WHICH ALLOWS US TO BOND ANY PIEZOELECTRIC CRYSTAL TO ANY SUBSTRATE. IN THE LAST THREE YEARS, BRIMROSE HAS BEEN A PIONEER… more
Company: Brimrose Corporation of America Agency/Program/Year/Phase: DOD / SBIR / 1987 / 1
Abstract: N/A
Company: Brimrose Corporation of America Agency/Program/Year/Phase: DOD / SBIR / 1987 / 1
Abstract: N/A
Company: Business & Technological Syste Agency/Program/Year/Phase: DOD / SBIR / 1987 / 2
Abstract: A CRUCIAL REQUIREMENT FOR SUCCESSFUL BATTLE MANAGEMENT IN A BALLISTIC MISSILE DEFENSE (BMD) SYSTEM IS PERFORMANCE OF THE TRACKING/CORRELATION FUNCTION. DUE TO THE FACT THAT THE DEFENSE SYSTEM ITSELF MAY BE UNDER ATTACK, IT IS IMPORTANT TO USE A DECENTRALIZED TRACKING/CORRELATION ARCHITECTURE TO… more
Company: Business & Technological Syste Agency/Program/Year/Phase: HHS / SBIR / 1987 / 1
Abstract: A VARIETY OF PROBES OF BRAIN FUNCTION HAVE BEEN DEVELOPED BYCLINICIANS AND NEUROSCIENTISTS BASED ON MEASUREMENT OF SCALP-RECORDED ELECTRICAL POTENTIALS EVOKED BY SPECIFIC STIMULI, SO-CALLED EVOKED POTENTIALS (EPS). SIGNAL ENHANCEMENT OF EPS IS TYPICALLY ACCOMPLISHED BY ENSEMBLE AVERAGING. IN THIS… more
Company: Caliber Inc Agency/Program/Year/Phase: DOD / SBIR / 1987 / 1
Abstract: A NEOPRENE HAVING UNDERSTOOD AND CONTROLLED COMPOSITION IS CRITICAL TO THE ACOUSTIC PERFORMANCE OF A TORPEDO TRANSDUCER. THIS APPROACH WILL COMPOUND THREE DIRECTIONS OF MODIFICATION TO A SIMPLE GUM NEOPRENE COMPOUND - FILLER, PLASTICIZER, AND PARTIAL POLYMER REPLACEMENT.A TOTAL OF 16 COMPOUNDS WILL… more
Company: Cemcom Research Associates Inc Agency/Program/Year/Phase: DOD / SBIR / 1987 / 1
Abstract: RESEARCH WILL BE CARRIED OUT TO INVESTIGATE THE FEASIBILITY OF CHEMICALLY BONDED CERAMICS (CBC) BASED ON HIGH STRENGTH CEMENTS AS REPLACEMENT MATERIALS IN VARIOUS HIGH TECHNOLOGY APPLICATIONS. ADVANCED CEMENTS HAVE STRENGTHS AT LEAST AN ORDER OF MAGNITUDE HIGHER THAN CONVENTIONAL CEMENT PRODUCTS.… more
Company: Center For Health Policy Agency/Program/Year/Phase: HHS / SBIR / 1987 / 1
Abstract: THE PRIMARY PURPOSE OF THIS PROJECT IS TO DEVELOP A PRACTICAL MANUAL FOR THE PLANNING, DESIGN, AND IMPLEMENTATION OF MEDICAID ALTERNATIVE DELIVERY SYSTEM (ADS) PROGRAMS. STATE MEDICAID PROGRAM EXPERIENCES WITH HEALTH MAINTENANCE ORGANIZATIONS AND OTHER ADS PROGRAMS HAVEBEEN MIXED, WITH SOME STATES… more
Company: Chemical Dynamics Corp Agency/Program/Year/Phase: NSF / SBIR / 1987 / 1
Abstract: REALISTIC YET REASONABLY SIMPLE INTERACTION POTENTIALS ARE ESSENTIAL INPUT FOR ANY COMPUTER SIMULATION INVESTIGATION. THREE-BODY OR OTHER SPECIAL TYPES OF INTERACTIONS (BEYOND PRESENT ISOTROPIC TWO-BODY POTENTIALS) ARE NECESSARY FOR SIMULATION STUDIES OF SEMICONDUCTOR PROCESSES. LACKING SUCH… more
Company: Chemical Dynamics Corp Agency/Program/Year/Phase: NSF / SBIR / 1987 / 1
Abstract: THIS PROGRAM INVESTIGATES THE USE OF A NEW MIMD COMPUTER SYSTEM, THE INTEL IPSC HYPERCUBE, FOR POTENTIAL USE AS A MO-LECULAR MODELINGSYSTEM. PHASE I WILL STUDY ALGORITHMS FOR EFFICIENTLY PROGRAMMING MOLECULAR DYNAMICS SIMULATION ON THIS SYSTEM WITH CONCURRENT REALTIME GRAPHICAL ANALYSIS. THE LATEST… more
Company: Cheung Laboratorytories, In Agency/Program/Year/Phase: HHS / SBIR / 1987 / 2
Abstract: THE EFFICACY OF HYPERTHERMIA AS A TREATMENT MODALITY FOR CANCER IS DEPENDENT UPON THE ABILITY TO HEAT THE ENTIRE TUMOR TO 42 DEGREES C OR GREATER. CURRENTLY AVAILABLE COMMERCIAL EQUIPMENT DOES NOT PROVIDE THIS CAPABILITY FOR DEEP-SEATED TUMORS. THE INVESTIGATION, DEVELOPMENT, AND EVALUATION OF… more
Company: Civilized Software, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1987 / 2
Abstract: MLAB IS A UNIQUELY POWERFUL, VERY HIGH-LEVEL MATHEMATICAL AND GRAPHICAL PROGRAMMING LANGUAGE. IT IS EXTREMELY VALUABLE TO THE RESEARCH COMMUNITY AT THE NIH AND OTHER BIOMEDICAL RESEARCH INSTITUTIONS. HOWEVER, MLAB RUNS ONLY ON DEC-10/20 COMPUTERS BECAUSE IT IS WRITTEN IN THE SAIL LANGUAGE, USES A… more
Company: C-MOTION, INC. Agency/Program/Year/Phase: HHS / SBIR / 1987 / 2
Abstract: WE PROPOSE TO USE THE GENE FOR ALPHA-1-ANTI-TRYPSIN (1-AT), A MODERATELY GLYCOSYLATED HUMAN SERUM PROTEIN, AS A SPECIFIC MODEL TO TEST THE FEASIBILITY OF USING BAKERS' YEAST (S. CEREVISIAE) AS A HOST MICROORGANISM FOR PRODUCTION OF HUMAN GLYCOPROTEINS WITH PHARMACEUTICAL APPLICATIONS. SPECIFICALLY,… more
Company: Cushing Associates Inc Agency/Program/Year/Phase: DOD / SBIR / 1987 / 1
Abstract: FOR THE ELECTROMAGNETIC FLOWMETER IT HAS BEEN THEORETICALLY AND EXPERIMENTALLY ESTABLISHED THAT THE FLOW-GENERATED VOLTAGE IS THE SAME WHETHER METERING CONDUCTIVE OR INSULATING LIQUIDS. IT HAS FURTHER BEEN THEORETICALLY AND EXPERIMENTALLY ESTABLISHED THAT THE EM FLOWMETER OPERATES OPTIONALLY AS A… more
Company: DEFENSE RESEARCH TECHNOLOGIES, INC. Agency/Program/Year/Phase: DOD / SBIR / 1987 / 1
Abstract: N/A
Company: Dvp, Inc. Agency/Program/Year/Phase: DOT / SBIR / 1987 / 2
Abstract: INDUCTIVE LOOPS HAVE BEEN USED IN RAODWAYS FOR VEHICLE SURVEILLANCE AND TRAFFIC CONTROL SYSTEMS SINCE THE LATE 1960'S. THESE EARLY SYSTEMS WERE PLAGUED WITH DRIFT AND ENVIRNMENTAL CHANGE PROBLEMS WHICH RESULTED IN UNRELIABLE OPERATION AND FREQUENT MAINTENANCE. MODERN LOOP SYSTEMS, AFTER TWO DECADES… more
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