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Company: Idexx Corp. Agency/Program/Year/Phase: HHS / SBIR / 1990 / 2
Abstract: THE LONG-TERM OBJECTIVES OF THIS PROJECT ARE TO DEVELOP METHODOLOGIES AND A KNOWLEDGE BASE THAT WILL ENHANCE THE UTILIZATION OF FELINE T-CELL LYMPHOTROPIC LENTIVIRUS (FTLV) AS A SMALL-LABORATORY ANIMAL MODEL OF HIV. IN PHASE I, A FTLV ANTIGEN TEST WILL BE DEVELOPED THAT WILL AUGMENT EXISTING… more
Company: IMMUCELL CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1990 / 1
Abstract: THE NUMBER OF CASES OF HUMAN DIARRHEA ATTRIBUTED TO CRYPTOSPORIDIUM PARVUM HAS INCREASED DRAMATICALLY IN THE LAST DECADE. IN IMMUNOCOMPROMISED INDIVIDUALS, MOST NOTABLYAIDS PATIENTS, CRYPTOSPORIDIOSIS CAN PRESENT AS A FULMINANT AND PERSISTENT DIARRHEA. THERE IS CURRENTLY NO KNOWN CHEMOTHERAPEUTIC… more
Company: Light Work Unlimited Agency/Program/Year/Phase: HHS / SBIR / 1990 / 1
Abstract: THE ULTIMATE GOAL OF PROJECT TRANSITION IS TO BRING ABOUT INCREASED EARLY INTERVENTION IN AND PREVENTION OF ABUSIVE ALCOHOL USE PATTERNS AMONG DIVORCED AND SEPARATED WOMEN WHO ARE KNOWN TO BE AT RISK OF SUBSTANCE ABUSE BY DEVELOPING LOW-COST, NONSTIGMATIZED EDUCATIONAL MATERIALS THAT CAN BE… more
Company: MERIDIAN MEDICAL SYSTEMS, LLC Agency/Program/Year/Phase: HHS / SBIR / 1990 / 2
Abstract: IT IS ESTIMATED THAT ALMOST 75,000 PERSONS WILL DIE EACH YEAR OF ACUTE RESPIRATORY INSUFFICIENCY CAUSED BY LUNG DISEASE. TO ADDRESS THIS PROBLEM, EXTRACORPOREAL MEMBRANE OXYGENATION (ECMO) IS USED TO PROVIDE EXTERNAL PUMPING AND MEMBRANE OXYGENATION TO ASSIST THE WEAKENED OR FAILING HEART. HEAT… more
Company: MERIDIAN MEDICAL SYSTEMS, LLC Agency/Program/Year/Phase: HHS / SBIR / 1990 / 2
Abstract: THE USE OF A MICROWAVE BASED SYSTEM WITH A SINGLE ANTENNA AND RADIOMETER TO DETECT THERMAL ANOMALIES IN THE BREAST HAS BEEN INVESTIGATED IN SEVERAL CLINICAL STUDIES. WE ARE NOW DEVELOPING A MULTIPLE ANTENNA SYSTEM, BASED UPON THE RESULTS OF THESE INITIAL STUDIES, TO PROVIDE GREATER RESOLUTION AND… more
Company: North Star Technology Inc Agency/Program/Year/Phase: DOD / SBIR / 1990 / 1
Abstract: THIS WORK WILL EXAMINE THE APPLICABILITY OF EXPERT SYSTEM TECHNOLOGY TO THE PROBLEM OF CONVERTING EXISTING PAPER-BASED TECHNICAL DOCUMENTATION TO DIGITAL FORMAT. THE MAJOR FOCAL POINTS OF THE WORK WILL INCLUDE CONSIDERATION OF THE KNOWLEDGE NECESSARY TO (1) DECOMPOSE THE TEXT INPUT INTO CATEGORIES… more
Company: North Star Technology Inc Agency/Program/Year/Phase: DOD / SBIR / 1990 / 1
Abstract: THIS WORK COMBINES THE PROBLEM STRUCTURING TOOLS AVAILABLE IN HYPERMEDIA PRODUCTS, WITH EXPERTISE REPRESENTATION APPROACHES FROM TRADITIONAL EXPERT SYSTEM TECHNOLOGY IN ORDER TO CREATE A DESIGN FOR AN ACQUISITION PROGRAM MANAGER'S ECP PREPARATION TOOL. THE TOOL WILL BE CAPABLE OF ASSISTING PMS IN… more
Company: Public Health Resource Group Agency/Program/Year/Phase: HHS / SBIR / 1990 / 2
Abstract: THE OBJECTIVE OF THIS RESEARCH IS TO DEVELOP A WRITTEN SET OF PLANNING PROTOCOLS, STATISTICAL ALGORITHMS, AND COMPUTER SOFTWARE THAT WILL ASSIST RURAL HOSPITALS AND THEIR COMMUNITIES IN EVALUATING THE EFFICACY AND FINANCIAL CONDITIONS OF THEIR HOSPITALS AND HEALTH-CARE DELIVERY SYSTEMS IN PLANNING… more
Company: Yankee Software Agency/Program/Year/Phase: HHS / SBIR / 1990 / 1
Abstract: DEVELOPMENT OF A NEW MICROCOMPUTER-BASED CATI SOFTWARE PACKAGE IS PLANNED THAT WILL OFFER ADVANTAGES OVER CURRENTLYAVAILABLE MICROCOMPUTER SOFTWARE BY FULLY UTILIZING NETWORKS, PROVIDING CAPABILITIES FOR MULTISITE AND MULTIMODE SURVEYS, AND OFFERING COMPATIBILITY WITH BOTH A FULL-FEATURED OPERATING… more
Company: BIODE, INC. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: BIODE, INC., WILL UTILIZE THE RESULTS OF ITS PHASE I RESEARCH TO DEVELOP A TOTALLY NEW SOLID-STATE SENSOR TECHNOLOGY FOR BIOLOGICAL MEASUREMENTS. THIS TECHNOLOGY IS BASED UPON THE MERGING OF TWO OTHER RELATIVELY NEW TECHNOLOGIES: NUCLEIC ACID PROBES (NUCLEIC ACID HYBRIDIZATION) WITH ACOUSTIC PLATE… more
Company: BIODE, INC. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: BIODE, INC., WILL UTILIZE THE RESULTS OF ITS PHASE I RESEARCH TO DEVELOP A TOTALLY NEW SOLID-STATE BIOSENSOR TECHNOLOGY FOR BIOLOGICAL MEASUREMENTS. THIS TECHNOLOGY IS BASED UPON THE MERGING OF TWO OTHER RELATIVELY NEW TECHNOLOGIES, MONOCLONAL ANTIBODIES (HYBRIDOMA TECHNOLOGY) WITH ACOUSTIC WAVE… more
Company: Gorham Advanced Materials Inst Agency/Program/Year/Phase: DOD / SBIR / 1989 / 1
Abstract: THIS PROPOSAL DESCRIBES A NOVEL PROCESSING TECHNOLOGY WHICH HAS THE POTENTIAL TO ACCELERATE THE DEVELOPMENT OF NICKEL ALUMINIDE COMPOUNDS INTO MATURE MATERIALS FOR ADVANCED APPLICATIONS. THIS TECHNOLOGY COMPRISES A CONTINUOUS, TWO PHASE PROCESS IN WHICH CLOSED POROSITY NICKEL ALUMINIDE BODIES ARE… more
Company: Great Eastern Mussel Farms, Inc. Agency/Program/Year/Phase: NSF / SBIR / 1989 / 2
Abstract: UTILIZATION OF MUSSEL (MYTILUS EDULIS) BOTTOM LEASES TO THEIR FULL POTENTIAL HAS BEEN HINDERED BY A LACK OF INFORMATION CONCERNING THE CARRYING CAPACITY OF OPEN CULTURE SYSTEMS. DEPLETION OF NATURAL FOOD PARTICLES IN THE BENTHIC BOUNDARY LAYER ABOVE MUSSEL BEDS HAS BEEN RECENTLY IDENTIFIED AS THE… more
Company: MERIDIAN MEDICAL SYSTEMS, LLC Agency/Program/Year/Phase: DOD / SBIR / 1989 / 2
Abstract: HYPOVOLEMIC SHOCK, SECONDARY TO TRAUMATIC EXSANGUINATION, IS THE MOST COMMON CAUSE OF DEATH IN SEVERELY INJURED SOLIDERS. TREATMENT OF HYPOVOLEMIC SHOCK AND ATTENDANT HYPOTHERMIA IS THE SUBJECT OF THE STUDY PROPOSED HERE. TO ADDRESS THE PROBLEM OF HYPOTHERMIA AND ITS ASSOCIATED COAGULOPATHY AND… more
Company: PEPIN ASSOC., INC. Agency/Program/Year/Phase: DOT / SBIR / 1989 / 2
Abstract: THE PROPOSED PROGRAM EXAMINES OPPORTUNITIES FOR LIGHTWEIGHT CONTAINMENT STRUCTURES IN AIRCRAFT AND ROTORCRAFT AND SEEKS TO DEVELOP FIBER REINFORCED MATERIALS AS THE ENERGY ABSORBING CORE OF POTENTIAL CONTAINMENT DESIGNS. THE PROGRAM BEGINS FROM BASELINE DESIGNS FOR FAN CONTAINMENT WHICH EMPLOY PLAIN… more
Company: Technology Systems Inc. Agency/Program/Year/Phase: DOD / SBIR / 1989 / 2
Abstract: DEVELOPMENT OF A PC-BASED FLIGHT INSTRUCTION TUTORING SYSTEM WILL IMPROVE THE MOST BASIC CAPABILITIES OF AIR FORCE FLIGHT PERSONNEL, STANDARDIZE INITIAL TRAINING OF THE BASIC CONCEPTS OF FLIGHT, PROVIDE A FOUNDATION FOR THE ADVANCEMENT OF MODERN TRAINING METHODS, AND ALLOW INNOVATIONS ADDRESSING… more
Company: Technology Systems Inc. Agency/Program/Year/Phase: DOD / SBIR / 1989 / 1
Abstract: ANALYSIS AND DEVELOPMENT OF A PARALLEL PHIGS PRIMITIVE CAPABILITY IS POSSIBLE USING AVAILABLE PARALLEL ARCHITECTURES AND SOFTWARE TOOLS. EVALUATION OF THE PHIGS PRIMITIVES, IDENTIFICATION OF POSSIBLE METHODS OF IMPLEMENTATION USING PARALLEL ARCHITECTURES, SELECTION OF A PHASE I APPROACH, THEORETICAL… more
Company: BIODE, INC. Agency/Program/Year/Phase: NSF / SBIR / 1988 / 1
Abstract: BIODE WILL UTILIZE THE RESULTS OF ITS PHASE I RESEARCH TO DEVELOP (PHASE II) AND COMMERCIALIZE (PHASE III) A TOTALLY NEW SOLID STATE SENSOR TECHNOLOGY FOR BIOLOGICAL MEASUREMENTS. THIS TECHNOLOGY IS BASED UPON THE MERGING OF TWO OTHER RELATIVELY NEW TECHNOLOGIES: MONOCLONAL ANTIBODIES (HYBRIDOMA… more
Company: Gorham Advanced Materials Inst Agency/Program/Year/Phase: DOD / SBIR / 1988 / 1
Abstract: THIS PROPOSAL DESCRIBES AND R&D PROGRAM, THE OBJECTIVE OF WHICH IS TO INITIATE DEVELOPMENT OF SILICON NITRIDE/SILICON CARBIDE WHISKER COMPOSITES FABRICATED BY GAS PRESSURE SINTERING AND CONTAINERLESS HOT ISOSTATIC PRESSING (HIP). THE TARGET MATERIALS WILL BE BASED ON CERAMIC MATRICES FORMED FROM… more
Company: MERIDIAN MEDICAL SYSTEMS, LLC Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: ACUTE OR CHRONIC FAILURE OF THE KIDNEYS RESULTS IN RAPID DEATH UNLESS NORMAL KIDNEY FUNCTION IS REPLACED BY DIALYSIS.DIALYSIS PURIFIES THE BLOOD IN A SELECTIVE WAY, REMOVING TOXIC SUBSTANCES VIA A SEMI-PERMEABLE MEMBRANE, OR FILTER. HEMODIALYSIS EMPLOYS AN ARTIFICIAL EXTRACORPOREAL MEMBRANE WHICH… more
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