Abstract:DESCRIPTION (provided by applicant): Once heralded as the holy grail, the capability of obtaining a comprehensive list of genes, proteins or metabolites that are different between disease and normal is routine today. And yet, the holy grail of high-throughput has not delivered so far. Even though… more
Abstract:Throughout the past decade, there has been increasing urgency to develop novel technologies for alternative energy sources. This is being driven by the consequential relationships of increased global consumption, rapidly diminishing fossil fuel reserves, growing national energy security concerns,… more
Abstract:DESCRIPTION (provided by applicant): The Problem: The lack of devices specifically designed for pediatric applications has been recognized by directives in the Pediatric Medical Device Safety and Improvement Act of 2007, included in Public Law 110-85, andthe Institutes of Medicine, which has… more
Abstract:DESCRIPTION (provided by applicant): Robotic Amputee Gait Capacity Assessment System Robotic prostheses can improve mobility for individuals with amputation, but assessment and prescription for each individual is difficult and errors are costly. We propose to determine the feasibility of a product… more
Abstract:Abstract - The goal of this work is to enhance the productivity and comfort of computer access for people whose impairments affect their ability to use the computer keyboard and mouse. In Phase I, we will develop and evaluate a software tool for the automatic configuration of computer keyboards. The… more
Abstract:Due to the complex wave propagation and vibration involved in dynamic loading, commonly used sensors, such as electrical resistance strain gauge and accelerometer, cannot adequately measure the true loading history without a specially designed mechanism. In the Phase I study, an innovative mechanism… more
Abstract:Heavy add-on-armor installed on the Bradley Fighting Vehicle has degraded the vehicle's mobility performance. Vehicle acceleration has declined to 80% of its original capability. To cost effectively modernize the mobility system, the final drive torque capacity must be significantly… more
Abstract:Michigan Aerospace Corporation proposes to develop an integrated LIDAR instrument capable of identifying icing conditions while also providing air data sensing capabilities. The resulting Raman Icing Detection System (RIDES) will be an integrated air data sensing and icing condition detection… more
Abstract:Volcanic ash is a significant hazard to aircraft engine and electronics and has caused damage to unwary aircraft and disrupted air travel for thousands of travelers, costing millions of dollars. Michigan Aerospace Corporation (MAC) proposes to demonstrate the concept feasibility of a Raman Light… more
Abstract:The successful landing of the large Mars rover Curiosity on August 5, 2012 outlined the increasing complexity of safely landing large rovers on the planet. A precise knowledge of the spacecraft speed is required in order to initiate the landing sequence near 900 mph; the present method uses IMUs to… more
Abstract:Design is the act of generating information that is used to make decisions or produce a product. Modern products are moving away from segregated disjointed systems and towards interdependent systems that utilize shared hardware and software resources (e.g. zonal power distribution, ethernet based… more
Abstract:The Phase I verified ADS-B-ER feasibility-based on compatibility with the ADS-B operational standards and design specs, bandwidth and the iPAD EFB capability for performing the trajectory computations for avoiding hazardous weather, terrain, traffic and restricted airspace. We then assured that… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project seeks to develop a method for the production of polycrystalline YAG laser gain media containing gradients of dopant in either linear or radial directions within the part. Such parts offer performance improvements for both output power… more
Abstract:Electromagnetic and particle modeling is an important part of the design and manufacturing of accelerator components, such as electron beam sources and RF accelerating cavities. The premier electromagnetic and particle modeling tools today allow users to exploit parallel computing… more
Abstract:Field emission cathodes are well known in the field of electron microscopy and extensively used because their very small source size (e.g.: sharpened end of a needle) can lead to very high- brightness electron beams. Recently, important developments in field-emission arrays have made them a… more
Abstract:In the proposed collider eRHIC, hadrons from one of the RHIC storage rings will interact with electrons accelerated in a six-pass energy recovery linac (ERL). The maximum energy of protons will be 250 GeV and the maximum energy of electrons will be 30 GeV. The machine will heavily rely on SRF… more
Abstract:Superconducting radio frequency (SRF) cavities are being successfully used for acceleration of charged particle beams worldwide. The application of the SRF cavities for manipulation of the beam properties in the transverse direction finds more and more applications. The use of superconducting… more
Abstract:The majority of radioisotopes used in the United States today come from foreign suppliers or are generated parasitically in large government accelerators and reactors. Both of these restrictions limit the availability of radioisotopes, especially short lived ones, and discourages the development… more
Abstract:Development of high-speed rail services in the US is one of the priorities of the current administration. High-speed rails have the potential to change the nations energy consumption landscape in transportation at a time when both the highway and railroad capacities are being saturated with… more
Abstract:DESCRIPTION: Biomarkers currently employed for the detection of organ toxicity are often not sensitive enough to detect the early stages of acute organ damage, i.e. at a stage when reducing or eliminating exposure to a toxin could prevent progression of organ damage or a disease process, nor do… more
Abstract:DESCRIPTION: In this SBIR Phase II PicoCal will develop a high throughput apparatus to measure changes in cell adhesion at the level of individual receptor-ligand interactions in real time. This tool finds critical applications in research and drug development and would allow researchers to study… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project aims to develop a micromachined patch-clamp probe that enables sub-cellular imaging, electrophysiology, and fluidic delivery at the nanoscale with control of applied force at pN levels. The probe can operate like a force sensing finger… more
Abstract:ABSTRACT: In this Phase I STTR project, we propose to demonstrate the feasibility of developing a low cost, compact, time-domain terahertz (TD-THz) spectrometer specifically for the characterization of semiconductor materials over a range of temperatures, electric fields, and magnetic fields. In… more
Abstract:In this Phase I SBIR project, we propose to demonstrate the feasibility of a Time-Domain Terahertz (TD-THz or THz) system for rapid determination of the composite heat damage to airframes. The method employed will be capable of inspecting for heat damage underneath paint and coatings to detect… more
Abstract:Undersea operational supremacy is foundational to continued U.S. security. This supremacy is partly rendered through clandestine operations. Though Navy submarine and surface ship signatures are measured at land-based silencing facilities or test ranges at sea, these signatures can degrade over time… more
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