Abstract:DESCRIPTION (provided by applicant): Death of photoreceptor cells is a consequence of many acute as well as chronic retinal diseases which lead to severe vision loss in patients. If photoreceptors could be helped to survive the period of disease, the visual outcomes for patients would be… more
Abstract:Project Abstract Active surveillance (AS) is becoming more accepted as a reasonable treatment option for men with low-risk prostate cancer (i.e. Gleason score 6, clinical stage T2a, PSA lt 10). Many AS protocols at major institutions call for a prostate saturation biopsy after initial diagnosis to… more
Abstract:DESCRIPTION (provided by applicant): In the USA, about 36 million adults suffer from hearing loss and three out of every 1,000 children are born deaf or hard-of-hearing. When conventional hearing aids provide no appreciable benefit, implantable electronicdevices using electrode arrays inside the… more
Abstract:Problem. The farming industry is a significant contributor of nutrients to the nation & #39;s waterways yet, as a non-point source, remains unregulated by the USEPA. Excessive nitrogen has created hypoxic zones in water bodies such as the Gulf of Mexico, which receives drainage from 41 percent… more
Abstract:The goal of this work is to provide the Navy with a new, ultra-small vibration suppression system for quartz oscillators, which will be used as a master clock reference for fast data rate sensor arrays, radar, anti-jamming, and other electronic countermeasures used in high vibration environments.… more
Abstract:The objective of this proposal is to demonstrate a generic package that provides high vacuum, temperature control and vibration isolation for a wide range of high performance (tactical and navigation grade) micromachined inertial sensors. Inertial sensors (accelerometers and gyroscopes) are now… more
Abstract:This Small Business Innovation Research Program (SBIR) Phase I project is to demonstrate the feasibility of the environment resistant resonant sensor (ERRS) process which will enable a next generation of high performance and high reliability sensors. In the last 5 years, microelectromechanical… more
Abstract:This Small Business Innovation Research Phase I project addresses the urgent need for new mouth guard materials that provide better protection. Despite widespread use of mouth guards in sports, there are more than 1 million dental injuries per year costing $500 million in the US alone. Akervall… more
Abstract:While most media attention in the wake of a terrorist attack, a natural disaster, or even a single building fire focuses rightly on the safety and wellbeing
of the general public, one often overlooked aspect of these catastrophic events is the extreme risk taken by first responders who enter… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project is focused on developing a one-piece functionally graded hybrid (fiber/particle) reinforced aluminum alloy matrix automobile brake rotor. Composite brake rotors offer increased weight savings, higher braking performance, and increased… more
Abstract:This Small Business Innovation Research Phase I project relates to the use of nano-structured chemicals in the processing of light-weight magnesium (Mg) alloys for high performance applications. It is postulated that reactive nano-structured chemicals such as polyhedral oligomeric silsesquioxane… more
Abstract:Diesel compression ratios are normally set high (16:1 to 23:1) for cold starting, yet data show optimum fuel efficiency and emissions occur at compression ratios below 14:1. The industry trend has been to steadily reduce compression ratio. Literature findings indicate that reducing Diesel… more
Abstract:Diesel engine manufacturers need a way to improve fuel economy as well as limit NOx and particulate emissions to meet upcoming federal, state, and global regulations. A large percentage of emissions and fuel consumption occurs during cold start and light to medium load operation. EMA proposes to… more
Abstract:DESCRIPTION (provided by applicant): For twenty years prolonged extracorporeal life support (ECLS ECMO) has been standard treatment for infants with severe heart or lung failure unresponsive to other treatment. The healthy survival rate in over 30,000 cases ranges from 40% in cardiac arrest to 95%… more
Abstract:DESCRIPTION (provided by applicant): The long range goal of this research is to develop and commercialize a novel device that provides mechanical airway support to treat obstructive sleep disordered breathing (SBD). The investigators invented and fabricated a machine that requires no electricity and… more
Abstract:DESCRIPTION (provided by applicant): There are 5 million births in the United States each year of which 500,000 are premature. Prematurity is associated with substantial mortality, morbidity, and escalating cost. The complications of premature birth include respiratory, gastrointestinal, and… more
Abstract:A significant challenge in scaling micro-propulsion devices up to 100s of Watts as well as scaling macro devices down to sub-kiloWatt level is the lack of a compatible neutralizer technology in the meso scale. Sub-kiloWatt EP systems require cathode technology that can produce sufficient current… more
Abstract:Vesitech, Inc. has developed a totally new class of water treatment technology utilizing novel carbon based electrodes that have been shown to electrochemically produce advanced oxidation (AO) species in-situ in contaminated water. Depending upon the electrode formulation and configuration, the… more
Abstract:DESCRIPTION (provided by applicant): Although oxaliplatin is a third-generation platinum drug, it has become the most prescribed amongst all platinum drugs overtaking its predecessors, cisplatin and carboplatin. To date, oxaliplatin has become an integralpart of various chemotherapy protocols,… more
Abstract:The Mackinac Technology Company is proposing to develop a novel antireflection film that will virtually eliminate the reflection of interior lighting on transit bus windshields and significantly improve driver visibility and passenger/pedestrian safety. Additives are incorporated into windshield… more
Abstract:DESCRIPTION (provided by applicant): A key component in any investigation of association and/or cause-effect relationships between the environment (e.g. air pollution, heat waves) and health outcomes (e.g. asthma, heart disease, cancer) is the availabilityof accurate models of exposure at the same… more
Abstract:Our overall goal is to enhance the overall behavior health and performance of personnel on (future potential) long-duration missions. We propose to use a local representation of the Second Life virtual world, along with our computer graphics and artificial intelligence background, to make a highly… more
Abstract:ABSTRACT: Inefficient handoffs and limited fault evaluation prevent the Air Force from achieving high daily rates of touch-labor maintenance and rapid return-to-service. We propose to research the best concepts in the commercial and military arenas to enhance existing aircraft maintenance… more
Abstract:Aerospace structures are often subjected to a broad spectrum of mechanical and/or aerodynamic excitations and, therefore, there is a real need for the development of a modeling technique which can be used for the vibroacoustic analysis, with high fidelity and adequate spatial and spectral… more
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