Abstract:DESCRIPTION (provided by applicant): The broad, long-term objective of this program is to develop the tools, protocols and facilities needed to produce multielectrode arrays (MEAs) out of known biocompatible materials for eventual use in humans. This willrequire construction and commissioning of a… more
Abstract:In many situations, aerospace structures are subjected to a wide frequency spectrum of mechanical and/or acoustic excitations and therefore, there is a need for the development of numerical modeling techniques that are applicable for the resolution of dynamic response of complex systems spanning the… more
Abstract:DESCRIPTION (provided by applicant): Micro-RNAs (miRNAs) are small non-coding RNAs that control gene expression by regulating messenger (mRNA) translation. miRNAs can act as oncogenes or tumor suppressors, and the differential expression of miRNAs has beencorrelated with cancer diagnosis, staging,… more
Abstract:DESCRIPTION (provided by applicant): In this grant proposal An Automated Antisense Design and Simulation Platform , a comprehensive molecular diagnostics software tool that is specific to the design and simulation of antisense oligonucleotide analog probes will be developed. The application of… more
Abstract:DESCRIPTION (provided by applicant): The discovery of new and interesting RNA sequences from genome sequencing projects, and the urgency to unravel their functions, has led to a dramatic push for novel structural determination techniques. Current experimental methods for three dimensional structure… more
Abstract:EDA, Inc., in partnership with Penn State, has shown previously that the concept of embedding fiber optics within ablative TPS material has merit and should yield a successful implementation of a spectrometer "window" during a Phase-II development program.Optical instrumentation, such as… more
Abstract:Advances in high power, photovoltaic technology has enabled the possibility of reasonably sized, high specific power, high power, solar arrays. At high specific powers, power levels ranging from 50 to several hundred kW are feasible. Coupled with gridded ion thruster technology, this power… more
Abstract:In this SBIR project, EMAG Technologies proposes to develop a comprehensive visual software environment for performance assessment and optimization of installed antenna and radome. The software will feature a full 3-D CAD modeler for platform setup and antenna-radome design. Fast full-wave solvers… more
Abstract:In this SBIR project we will develop an integrated software framework for RF system-of-systems simulation. The framework will feature a number of"Point Tools"that can address and solve certain types of problems very efficiently. The primary concept is to decompose a large computational… more
Abstract:The objective of this SBIR project is to design compact wideband antennas for military vehicular platforms using metamaterial concepts. Specifically, we will use some of the metamaterial surface concepts that have been recently developed at the University of Michigan for antenna miniaturization,… more
Abstract:In this SBIR project, we propose to expand the brick tracing algorithm originally developed for indoor wave propagation modeling to a fully 3-D"Block Tracing"algorithm, in which a large structure is decomposed into a number of elementary blocks, either periodic or aperiodic. The blocks can… more
Abstract:In this SBIR project, we propose to extend the method of numerically constructed characteristic basis functions (NCCBF) that was developed under a pervious NAVSEA-funded SBIR for the modeling of coupling effects in large phased arrays. This efficient matrix compression technique will be extended to… more
Abstract:The proposed SBIR Phase II project is to develop miniature light-weight high-functionality multi-sensor systems that meet the requirements for prognostics and health management of military equipment, and their life cycle management and condition-based maintenance. The systems integrate temperature,… more
Abstract:The size of the latest generation of wind turbines is outstripping the capabilities of the materials and techniques used to manufacture them. As wind turbines are made larger to improve efficiency, composites with improved mechanical properties and long term performance are required to avoid… more
Abstract:This Small Business Technology Transfer (STTR) Phase II project will develop a microphone for the test and measurement (T & M) market that utilizes piezoelectric microelectromechanical systems (MEMS) technology. During Phase I of this project, feasibility was demonstrated by building and testing… more
Abstract:Improving the acoustical environment is critical in aeronautics. Airports and aeronautical systems manufacturers are facing ever-increasing demands to reduce noise levels. Aeronautical applications require the use of high quality microphones with a large dynamic range, sometimes in large arrays. … more
Abstract:The U.S. Army is seeking ways to improve mission capability of small Autonomous Unmanned Ground Systems (AUGS) power systems. The challenges with AUGS stem from proprietary nature of information and control of vehicle platforms. The proprietary information is important for robot manufacturers… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project seeks to address a need in science education that is non-linearly becoming a serious problem. In general, educational technology has had a weak track record for positively impacting student understanding in the area of science. Research… more
Abstract:Auxiliary power units (APU) offer potential to improve operational efficiency and provide significant tactical advantage for surveillance missions conducted from land vehicle platforms. Current installations have resulted in higher than acceptable noise levels, adversely impacting the ability to… more
Abstract:DESCRIPTION (provided by applicant): Once heralded as the Holy Grail, the capability of obtaining a comprehensive list of genes, proteins or metabolites that are different between disease and normal is routine today. And yet, the holy grail of high-throughput has not delivered so far. Even though… more
Abstract:DESCRIPTION (provided by applicant): This is a Resubmission of an NIH Phase II SBIR Renewal Application directed towards developing and optimizing compounds that are capable of stimulating IRS2 foundation for the treatment of Type II diabetes. If successful, such compounds may also be useful for the… more
Abstract:An increasing proportion of eggs produced world-wide are brown or brown-speckled eggs. In addition, egg production methods, such as free-range and organic poultry cultivation methods, increase the variety of contaminants that can be deposited on eggs. Old technology that inspects white eggs has… more
Abstract:Coherix will proceed to define in detail, design, develop, construct, deliver, install and support a Holomapper-C prototype system for mapping of a variety of curved naval equipment surfaces at the micron and sub-micron level of resolution to detect and measure corrosion effects and other similar… more
Abstract:The Army uses intensified fuel injection systems on a number of their diesel powered vehicles. These systems are currently limited to injection pressures of about 20,000 psi. In an effort to increase thermal efficiiency (fuel economy), raise power output and operate on a variety of heavy hydrocarbon… more
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