Abstract:DESCRIPTION (provided by applicant): This proposal describes development and evaluation of an innovative, web-based, educational, mystery video game, N Sector that will engage a wide diversity of high school students in and out of classrooms, increase their knowledge of neuroscience, and promote… more
Abstract:DESCRIPTION (provided by applicant): Many prescribed drugs exhibit drug-drug interactions due to up-regulation or inhibition of specific P450 enzymes. According to a recent guidance from the FDA, CYP1A2, CYP2B6, and CYP3A4 induction should be evaluated inat least an in vitro system. Enzymatic… more
Abstract:DESCRIPTION (provided by applicant): The long-term goal of this project is to obtain FDA approval to market Poloxamer-188 (P- 188) for the prevention and treatment of dilated cardiomyopathy (DCM) and heart failure (HF) in Duchenne muscular dystrophy (DMD)patients. DMD is a debilitating and fatal… more
Abstract:NSF invites funding requests from current Small Business Innovation Research and Small Business Technology Transfer (SBIR/STTR) Phase II grantees to perform collaborative research with an Engineering Research Center (ERC). The goals of this collaborative effort are to provide a mutually beneficial… more
Abstract:Picometrix's time-domain terahertz (TD-THz) non-destructive evaluation (NDE) technology could be used to inspect space flight structures such as inflatable space habitats, thermal protection systems (TUFI-type tiles, SOFI TPS), for voids, disbonds, and damage such as tearing and… more
Abstract:In this Phase I SBIR project we propose to demonstrate the key elements of a practical, field-deployable non-contact time-domain terahertz (TD-THz) system for rapid detection of submarine hull defects such as corrosion and gouges hidden beneath acoustic hull coatings, hull coating material defects,… more
Abstract:ABSTRACT: Direct Digital Manufacturing (DDM) of aircraft metallic components is an emerging and innovative manufacturing process, which can create or repair metallic parts directly from powder metal. DDM promises cost, time and efficiency benefits over traditional machining processes (in which… more
Abstract:In the Navy, severe seawater corrosion is the main cause for damage and failure of high value components in submarine or other vessel components, and weapon systems. While replacement of these components are expensive and time consuming, in-situ repair is challenging due to the geometry constraints… more
Abstract:Natural disasters occur around the world all too frequently. When they occur, humanitarian aid and disaster relief (HADR) is needed quickly even in inaccessible locations due to either the natural terrain, or in some cases due to the disaster itself. Due to the scope of these disasters, some form of… more
Abstract:Naval operations with towed arrays have identified areas for improvements including performance, power consumption and reliability. The SeaLandAire Technologies, Inc. / L-3 Chesapeake Sciences Corporation team will address these concerns by incorporating a cost effective, high performance, small… more
Abstract:The US Navy has successfully developed a man-portable, X-class Unmanned Surface Vessel for shallow water coastal and riverine operations. Although the prototype USV has proven its utility during initial test and evaluation, several key technological hurdles remain. Increasing the top speed and… more
Abstract:ABSTRACT: In today"s warfare, accurate payload placement is necessary to maintain the tactical advantage we have been fostering throughout our history. Continuing evolution in air to ground mission objectives has brought new opportunities to technologically evolve the state of the art in… more
Abstract:A small, lightweight, man-packable Autonomous Underwater Vehicle (AUV) would provide significant advantages for covert reconnaissance and mapping applications in riverine environments. Presently, the smallest AUVs used by the Navy are still too heavy (approximately 40 lbs dry weight) and were not… more
Abstract:The Army as well as other branches of the Department of Defense (DoD) have made a substantial investment in synthetic scene generation for the development and testing of sensor and weapon systems. The synthetic scenes have been developed for programs concerning: 1) missile system and unmanned aerial… more
Abstract:The goal of the Urban Time-to-Detect Simulator for Combat Developers project is to develop and demonstrate a physics-based, calibrated, multi-modal simulator to evaluate vehicle detectability in urban environments. The effort has the potential to significantly enhance simulators for vehicle… more
Abstract:The revolution in simulation and virtual technologies for training is enabling learners to practice skills and learn in realistic environments. Researchers are also seeking to develop algorithms that can tailor learner practice to the estimated abilities and needs of individual students, offering… more
Abstract:SoarTech proposes to research and design an intelligent, multi-vehicle operator control unit that we call Sapient. Sapient will monitor the mission and behavior of a team of heterogeneous UVs and 1. present the user with filtered, focused information about the mission, 2. detect and project… more
Abstract:The USMC Combat Hunter program trains warfighters to be"combat hunters,"providing instruction for combat profiling, tracking, and enhanced observation. Combat Hunter is delivering highly successful training for those warfighters who have opportunity to participate. Computer-based training… more
Abstract:Current Mine Countermeasure (MCM) operations attempt to balance risk to commander"s intent and time via processes that are staff and time intensive. Existing tools such as MEDAL have helped to alleviate some of this, but those tools lack an comprehensive understanding of the uncertainties… more
Abstract:ABSTRACT: Demand for Remotely Piloted Aircraft (RPA) within the U.S. Military has significantly increased over the past decade, including Micro-Air Vehicles (MAVs). However, effective use of these systems has been hindered by the lack of natural interfaces for controlling them. Currently multiple… more
Abstract:Unmanned Ground Vehicles (UGVs) currently deployed on the battlefield are driven with Operator Control Units (e.g., joystick or point-and-click interface), which requires the full attention of an operator. This means the operator cannot concentrate on maintaining situational awareness, security, or… more
Abstract:Current Unmanned Air Systems (UAS) require a great deal of specialized training and experience to use effectively. Furthermore, their use is dominated by a paradigm of control in which a highly trained operator is giving very precise, low-level commands to a UAS. As UAS become more autonomous, they… more
Abstract:Efforts to replace metals with composites in shipboard applications have emphasized the use of brominated vinyl esters as fire-retardant polymers. Despite their relatively low cost and ease of fabrication, such halogenated polymers produce toxic and potentially carcinogenic gases; their… more
Abstract:The purpose of the proposed Phase I research is to develop and implement tools to model the effects of the atmosphere on synthetically generated IR scenes to be used in ballistic missile defense system assessment.These effects include scattering, absorption and emission due to gases and aerosols,… more
Abstract:ABSTRACT: The ThermoReg thermal model was developed to solve for tissue temperatures resulting from radio frequency (RF) heating using a voxel-based, heterogeneous tissue description of the human body. Although ThermoReg has been parallelized to run on high-performance computer clusters, the… more
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