Abstract:Auxiliary power units (APU) offer potential to improve operational efficiency and provide significant tactical advantage for surveillance missions conducted from land vehicle platforms. Current installations have resulted in higher than acceptable noise levels, adversely impacting the ability to… more
Abstract:DESCRIPTION (provided by applicant): Helminth infections are responsible for severe health problems worldwide, in both human and animal populations. It is estimated that 2-3 billion people, mainly from rural and impoverished regions of the world suffer from disease due to parasitic nematodes;… more
Abstract:So-called tabletop accelerators are a holy-grail of high energy/high field physics and, if developed, as indicated by the Department of Energy in the Accelerators for America report, will spur a revolution in particle physics discoveries and also in medical treatments. This is because planned… more
Abstract:DESCRIPTION (provided by applicant): Leukocytes (LE) are major contributors to the pathogenesis and progression of many clinical inflammatory disorders, including the systemic inflammatory response syndrome, sepsis and acute respiratory distress syndrome.The need for new and innovative therapies to… more
Abstract:This Small Business Innovation Research Phase I project addresses the development of a novel low-profile miniature wireless pressure sensing system, customized for industrial and medical applications where a small-sized, low cost, low-profile (flat) sensor is required. These miniature wireless… more
Abstract:DESCRIPTION (provided by applicant): The long-term goal of this project is to develop prosthetic foot technology that can function differently for walking and standing tasks. Although current prostheses can be very effective for particular tasks (e.g. walking, running, or standing), an amputee must… more
Abstract:ABSTRACT: Michigan Aerospace Corporation, in cooperation with the University of Michigan"s Department of Atmospheric, Oceanic, and Space Sciences, will refine existing upper atmospheric models and apply them to the problem of predicting satellite drag. The primary goal of this Phase 1 project… more
Abstract:Michigan Aerospace Corporation (MAC) proposes to advance NASA's nonintrusive spatially- and temporally-resolved Interferometric Rayleigh Scattering (IRS) technology to perform additional multiple properties measurements in high-speed flows. In particular, an instantaneous nonintrusive Optical… more
Abstract:During this Phase I, Michigan Aerospace Corporation will adapt the design of an optical MEMS seismometer for lunar and other planetary science instrumentation. The optical MEMS based seismometer takes advantage of the high Q of morphological dependent resonances and can be sensitive to a few nano-g… more
Abstract:Mobile Intelligence Corporation (MIC) and Wayne State University propose a virtual teleoperation and visual landmark navigation system for UGV teleoperation in buildings, tunnels and caves. The challenge is search and navigation in complex structures with sparse visual cues, high-latency… more
Abstract:Teleoperation of high speed ground robots is very difficult. People use an enormous amount of proprioceptive cues to estimate safe travel speeds and compensate for motion jitter. Simply moving the controls off-board takes away those cues, and makes the task much harder. Worse, the reality of radio… more
Abstract:Munro offer an innovatiive, intelligent, fully integrated hardware and software cockpit system solution for handling many General Aviation (GA) and UAV emergencies so as to minimize NextGen ATM disruption while saving lives. This ADS-B-ER system will provide GA airplanes and UAVs automated -ER… more
Abstract:The DOE Systems Biology Knowledgebase (Kbase) was envisioned to provide a framework to support modeling of dynamic cellular processes of microorganisms, plants and metacommunities. The Kbase will provide the tools and data to permit rapid iteration of experiments that draw on a variety of data types… more
Abstract:There is a need for an infrared window material that can replace single crystal sapphire in airborne applications. In order to do so, the alternate must possess optical transmission, optical scatter, mechanical strength, and mechanical stiffness comparable to sapphire while costing significantly… more
Abstract:Superconducting radio frequency (SRF) accelerating cavities are being successfully used for acceleration of electron beams worldwide. The use of superconducting structures helps maximize the accelerating gradient, which is a highly desirable trait for applications involving linear accelerators or… more
Abstract:In the last ten to fifteen years, superconducting radio frequency cavities have begun to be utilized in accelerators for light sources, first as passive cavities for stabilizing the beam and later in the accelerating sections. In this SBIR proposal, Niowave will build and test the quarter-wave… more
Abstract:Many lines of research currently ongoing at storage ring light sources would benefit from intense, tunable, few picoseconds x-ray pulses for time-domain experiments. The use of a deflecting cavity has several advantages over other proposals to produce these pulses. A crab cavity does not… more
Abstract:Compact free electron lasers (FELs) based on superconducting energy recovery linacs are poised to open a new market of tunable high power lasers. The primary impediment to realizing these FELs is an affordable electron source that operates continuous wave (CW) with moderate average current,… more
Abstract:Superconducting radio frequency (SRF) cavities are being successfully used for acceleration of charged particle beams worldwide. The application of the SRF cavities for manipulation of the beam properties in the transverse direction finds more and more applications. The use of superconducting (SC)… more
Abstract:The majority of radioisotopes used in the United States today come from foreign suppliers or are generated parasitically in large government accelerators and reactors. Both of these restrictions limit the availability of radioisotopes, especially short lived ones, and discourages the development… more
Abstract:DESCRIPTION (provided by applicant): This proposal describes development and evaluation of an innovative, web-based, educational, mystery video game, N Sector that will engage a wide diversity of high school students in and out of classrooms, increase their knowledge of neuroscience, and promote… more
Abstract:DESCRIPTION (provided by applicant): Many prescribed drugs exhibit drug-drug interactions due to up-regulation or inhibition of specific P450 enzymes. According to a recent guidance from the FDA, CYP1A2, CYP2B6, and CYP3A4 induction should be evaluated inat least an in vitro system. Enzymatic… more
Abstract:DESCRIPTION (provided by applicant): The long-term goal of this project is to obtain FDA approval to market Poloxamer-188 (P- 188) for the prevention and treatment of dilated cardiomyopathy (DCM) and heart failure (HF) in Duchenne muscular dystrophy (DMD)patients. DMD is a debilitating and fatal… more
Abstract:NSF invites funding requests from current Small Business Innovation Research and Small Business Technology Transfer (SBIR/STTR) Phase II grantees to perform collaborative research with an Engineering Research Center (ERC). The goals of this collaborative effort are to provide a mutually beneficial… more
Abstract:Picometrix's time-domain terahertz (TD-THz) non-destructive evaluation (NDE) technology could be used to inspect space flight structures such as inflatable space habitats, thermal protection systems (TUFI-type tiles, SOFI TPS), for voids, disbonds, and damage such as tearing and… more
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