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Displaying 1726 – 1750 of 1961 Awards
Company: Apa Optics, Inc. Agency/Program/Year/Phase: DOD / SBIR / 1990 / 1
Abstract: N/A
Company: Apeiron Inc Agency/Program/Year/Phase: DOD / SBIR / 1990 / 1
Abstract: THE KEY PROBLEM TO BE ADDRESSED IN PHASE I OF THIS PROJECT WILL BE TO DETERMINE THE FEASIBILITY OF A NOVEL POSITION MEASURING SYSTEM FOR A FAMILY OF COMPUTER CONTROLLED MACHINE TOOLS. THE MULTIPLE LASER MEASUREMENT SYSTEM (MLMS), WHICH FORMS THE BASIS OF THIS PROPOSAL, WILL MEASURE THE (X, Y, Z)… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1990 / 2
Abstract: MANY LIFE-SAVING PROCEDURES NOW REQUIRE THE INSERTION OF LONG-DWELLING PERCUTANEOUS CATHETERS (I.E., SEVERAL TYPES OFVASCULAR CATHETERS AND PERITONEAL DIALYSIS CATHETERS). IDEALLY, THESE CATHETERS SHOULD BE BOTH COMPATIBLE WITH THE TISSUES THEY ENCOUNTER AND PROVIDE AN EFFECTIVE BARRIER AT THE… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1990 / 2
Abstract: ENZYME DEFICIENCIES ASSOCIATED WITH INBORN METABOLIC DEFECTSARE USUALLY FATAL WITHIN THE FIRST FEW YEARS OF LIFE. TREATMENTS SUCH AS DIET MANIPULATION, GENE REPLACEMENT THERAPY, CHEMOTHERAPY, TRANSFUSIONS, TRANSPLANTATIONS, AND PERITONEAL DIALYSIS HAVE PRODUCED MARGINAL IMPROVEMENTS IN THESE… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1990 / 2
Abstract: NO ADEQUATE SMALL DIAMETER VASCULAR PROSTHESES ARE NOW COMMERCIALLY AVAILABLE, WITH THE MAJOR REASONS FOR LOSS OF PATENCY BEING THROMBUS FORMATION AND NEOINTIMAL FIBROUS HYPERPLASIA. ALSO, GRAFTS ARE OFTEN THE SITE OF CHRONIC INFECTIONS. THIS PROPOSED FEASIBILITY STUDY EXPECTS TO IMPROVE THE… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1990 / 1
Abstract: INFECTIONS ARE THE MOST SERIOUS COMPLICATION OF MEDICAL DEVICES. A HIGH INCIDENCE OF INFECTION IS ASSOCIATED WITH ALL DEVICES, INCLUDING CONTACT LENSES, CATHETERS, DIALYSIS MATERIALS, AND CARDIOVASCULAR IMPLANTS. INFECTIONS ARE TREATED AS THEY OCCUR, BUT PREVENTION IS THE MOST PROMISING APPROACH TO… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1990 / 1
Abstract: THIS PROJECT WILL DEVELOP A METHOD FOR USE IN NONLABORATORY ENZYME IMMUNOASSAY DETECTION KITS THAT WILL USE MODIFIED ANTIBODY FOR EXTRACTING HYDROPHOBIC CHEMICALS (ANALYTES) FROM A LIPID OR OIL PHASE IN A SAMPLE WITHOUT THE USE OF FLAMMABLE OR TOXIC SOLVENTS. THE CONCEPT IS TO COVALENTLY COUPLE A… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1990 / 1
Abstract: THIS RESEARCH WILL DEVELOP METHODS TO SIMULTANEOUSLY IMMOBILIZE AND COVALENTLY CROSS-LINK ANTIBODIES OR ANTIGENS ONTO POLYSTYRENE TUBES OR MICROTITER PLATES. THE COVALENTLYIMMOBILIZED ANTIBODIES WILL BE STABILIZED BY MULTIPOINT COUPLING TO HYDROPHILIC POLYMERS ON THE POLYSTYRENE SURFACE. THUS, THE… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: DOD / SBIR / 1990 / 1
Abstract: A PROJECT IS PROPOSED TO DEVELOP A BIOSENSOR FOR MEASURING PATHOGENIC MICROORGANISMS IN WATER BY MEASURING CHANGES IN CONDUCTANCE ACROSS MICROPOROUS, POLYCARBONATE MEMBRANE COATE WITH SPECIFIC ANTIBODIES. THE MEMBRANES WILL BE COATED WITH HYDROPHILIC POLYMERS USING PHOTOCHEMICAL COUPLING. ANTIBODIES… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1990 / 1
Abstract: CURRENTLY USED URINARY CATHETERS PRODUCE PAIN UPON INSERTION, INJURE ADJACENT TISSUE, AND CAUSE HIGH RATES OF BACTERIAL INFECTIONS. THESE ADVERSE EFFECTS ARE MEDIATED BYUNDESIRABLE SURFACE PROPERTIES OF THE CATHETER POLYMERS. THIS PHASE I PROJECT WILL UTILIZE PHOTOIMMOBILIZATION TECHNOLOGY TO… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1990 / 2
Abstract: IMMOBILIZATION OF BIOMOLECULES RESULTS IN GREAT LOSSES OF SPECIFIC ACTIVITIES OF THE IMMOBILIZED MOIETIES. THE USE OF HYDROPHILIC SPACERS BETWEEN THE BIOMOLECULES AND THE MATRIX RESULTS IN IMPROVED ACTIVITIES. HOWEVER, FACILE INTRODUCTION OF SUCH SPACERS ONTO MANY INSOLUBLE SUPPORTS ISDIFFICULT… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1990 / 1
Abstract: THE GOAL OF THIS PROJECT IS TO DEMONSTRATE THE BENEFIT OF UTILIZING PHOTOCHEMISTRY AS A GENERIC METHOD FOR INTRODUCINGBONDED, SLIPPERY COATINGS TO MEDICAL DEVICES. IT IS ANTICIPATED THAT THIS APPROACH WILL BE SUPERIOR TO CURRENT METHODS. THIS TECHNOLOGY WILL BE USED TO PREPARE SURFACES THAT ARE… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: DOD / SBIR / 1990 / 1
Abstract: N/A
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1990 / 1
Abstract: N/A
Company: Camas Diagnostic Co Agency/Program/Year/Phase: USDA / SBIR / 1990 / 1
Abstract: A NEED EXISTS FOR THE DEVELOPMENT OF A LOW COST, RAPID IDENTIFICATION/MONITORING TEST KIT FOR POTENTIAL PATHOGENS IN FOOD PRODUCTS. A MAJOR INNOVATION WOULD INCREASE THE SCREENING OF DISEASE ORGANISMS WHILE MONITORING POTENTIAL PATHOGENS IN FOOD. THE PROPOSED RAPID EIA-BASED DIAGNOSTIC TEST KIT IS… more
Company: Camas Diagnostic Co Agency/Program/Year/Phase: DOD / SBIR / 1990 / 1
Abstract: THE US MARINE CORPS HAS A DIRECT NEED TO MAINTAIN THE HEALTH AND FUNCTIONAL EFFECTIVENESS OF ITS PERSONNEL AGAINST A VARIETY OF DANGEROUS BIOLOGICAL AGENTS. METHODS TO DETECT THESE AGENTS IN ENVIRONMENTAL OR FIELD SAMPLES MUST BE DEVELOPED FOR USE IN THE NBC LABORATORY PROGRAM. THE PROPOSED NOVEL… more
Company: Cyberoptics Corp Agency/Program/Year/Phase: DOD / SBIR / 1990 / 1
Abstract: TO ENSURE RELIABLE PRODUCTION OF CARTRIDGE CASINGS, CRITICAL DIMENSIONS, SUCH AS THE PLACEMENT AND SIZE OF THE PRIMER CUP AND VENT HOLE, MUST BE ACCURATELY MAINTAINED. CURRENTLY, THERE IS NO ABILITY TO MEASURE CRITICAL DIMENSIONS OF THE PRIMER CUP DURING THE PRODUCTION OF THE 5.56MM CARTRIDGE CASING… more
Company: Daina Agency/Program/Year/Phase: DOD / SBIR / 1990 / 2
Abstract: FUTURE MILITARY AVIONICS SYSTEMS WILL REQUIRE AT LEAST AN ORDER OF MAGNITUDE IMPROVEMENT IN MEAN TIME BETWEEN CRITICAL FAILURES. TO ACHIEVE THIS GOAL INNOVATIVE FAIL-SAFE FAULT-TOLERANT ELECTRONIC SYSTEM DESIGN CONCEPTS WILL BE NEEDED. THE APPROACH PROPOSED BY DAINA WILL BE BASED ON THE USE OF… more
Company: Daina Agency/Program/Year/Phase: NSF / SBIR / 1990 / 1
Abstract: THERE IS A GROWING NATIONAL NEED TO PROVIDE RESEARCHERS WITHHIGH-SPEED AND COST-EFFECTIVE COMPUTERS CAPABLE OF HANDLING COMPUTATION-INTENSIVE STATISTICAL AND FORECASTING PROBLEMS. EXAMPLES OF SUCH STATISTICAL ANALYSES INCLUDE BOOTSTRAPPING AND PROJECTION PURSUIT REGRESSION. WHILE SUPERCOMPUTERS ARE… more
Company: DATA SCIENCES INTERNATIONAL, INC Agency/Program/Year/Phase: USDA / SBIR / 1990 / 1
Abstract: WE PROPOSE TO ASSESS THE FEASIBILITY OF AN AUTOMATED MEANS OF DETERMINING WHEN TO INSEMINATE DAIRY CATTLE IN ORDER TO IMPROVE REPRODUCTIVE PERFORMANCE. POOR REPRODUCTIVE PERFORMANCE IS THE MOST COSTLY MANAGEMENT PROBLEM DAIRY PRODUCERS FACE, AND FAILURE TO DETERMINE THE PROPER TIME TO ARTIFICIALLY… more
Company: Digiplan Inc Agency/Program/Year/Phase: HHS / SBIR / 1990 / 1
Abstract: SIGNIFICANT INCREASES IN LIFE EXPECTANCIES WOULD INCREASE ANNUITY COSTS AND WOULD REQUIRE ADDITIONAL RESERVES TO FUND CONTRACTS NOW IN BENEFIT. IT IS IMPORTANT THAT SUCH PLANS CONTINUE TO BE SOUNDLY FUNDED SO THAT FUTURE OBLIGATIONS CANBE MET. THE OBJECTIVE OF THIS RESEARCH IS TO DETERMINE THE SIZE… more
Company: ECOCHEM RESEARCH, INC. Agency/Program/Year/Phase: USDA / SBIR / 1990 / 1
Abstract: NITROGEN IS A LIMITED MINERAL NUTRIENT IN MANY AGRONOMIC SYSTEMS. LEGUMINOUS CROPS SUCH AS SOYBEAN AND ALFALFA USE BOTH SOIL NITROGEN AND, WHEN SUITABLE STRAINS OF THE NITROGEN-FIXING MICROSYMBIONTS BRADYRHIZOBIUM AND RHIZOBIUM ARE AVAILABLE, ATMOSPHERIC NITROGEN. IT HAS BEEN ESTIMATED THAT THE 50… more
Displaying 1726 – 1750 of 1961 Awards
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