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State:Minnesota
Company: Hamilton Maurer International Agency/Program/Year/Phase: EPA / SBIR / 1987 / 1
Abstract: N/A
Company: I-systems (intelligent Systems Agency/Program/Year/Phase: DOD / SBIR / 1987 / 1
Abstract: THIS PROPOSAL WILL DETERMINE THE MERIT AND FEASIBILITY OF A RECOMMENDED METHODOLOGIES (WHICH BEST LINK THE ADA DEVELOPMENT ENVIRONMENT, WITH THE RAPID PROTOTYPING DEVELOPMENT PROCESS ASSOCIATED WITH AI APPLICATIONS THAT ARE WRITTEN IN EITHER LISP OR PROLOG LANGUAGE) BY MAPPING BETWEEN APSE AND ASE… more
Company: London Diagnostics Inc Agency/Program/Year/Phase: HHS / SBIR / 1987 / 1
Abstract: THE AIM OF THIS PROJECT IS TO DEMONSTRATE AN IMMUNOMETRIC ASSAY FOR CANDIDA ANTIGEN (MANNAN) USING ACRIDINIUM ESTERS AS A CHEMILUMINESCENT LABEL. THIS WILL LEAD TO A TECHNIQUE FOR THE DETECTION OF FUNGAL ANTIGENS THAT REQUIRES HIGH SENSITIVITY, BY A METHOD THAT IS SIMPLER, SAFER, AND CHEAPERTHAN… more
Company: London Diagnostics Inc Agency/Program/Year/Phase: HHS / SBIR / 1987 / 1
Abstract: THE AIM OF THIS PROJECT IS TO DEMONSTRATE THE FEASIBILITY OF AN IMMUNOASSAY FOR INSULIN, USING ACRIDINIUM ESTERS AS A CHEMILUMINESCENT LABEL. THIS WILL LEAD TO A TECHNIQUE FOR THE DETECTION OF POLYPEPTIDE HORMONES THAT IS FASTER AND MORE SENSITIVE, AND REMOVES THE NEED FOR (125)I-LABELED PEPTIDES OR… more
Company: Molecular Genetics Inc. Agency/Program/Year/Phase: NSF / SBIR / 1987 / 1
Abstract: BOVINE VIRAL DIARRHEA VIRUS (BVDV) IS A VERY IMPORTANT BOVINE DISEASE AGENT, HAVING CONSIDERABLE ECONOMIC IMPACT ONCATTLE PRODUCERS DIRECTLY AND THE BIOLOGICS INDUSTRY VIA PRODUCT CONTAMINATION. CURRENT CONTROL AND DETECTION METHODS ARE INADEQUATE, AS IS THE BASIC UNDERSTANDING OF THEVIRUS, ITS… more
Company: Novcom Systems Inc Agency/Program/Year/Phase: ED / SBIR / 1987 / 1
Abstract: CURRENTLY, THERE ARE NO FULL PAGE BRAILLE DISPLAY DEVICES ON THE MARKET. DESPITE THE DESIRABILITY AND OBVIOUS BENEFITS OF SUCH A PRODUCT, TRADITIONAL ENGINEERING APPROACHES HAVE RESULTED IN MANUFACTURING DESIGNS WHICH ARE PROHIBIITIVELY EXPENSIVE TO PRODUCE. AFTER CRITICAL EXAMINATION OF DOZENS OF… more
Company: Prismoid Optical Agency/Program/Year/Phase: DOD / SBIR / 1987 / 1
Abstract: THIS PROJECT WILL INVESTIGATE DIFFERENT AND UNUSUAL METHODS OF COMBINING OPTICAL POWER WITHIN THE SPLITTER PLATE. SUCH ACCOMPLISHMENTS WOULD SAVE WEIGHT, MINIMIZE VOLUME AND EXTEND A DESIGN DEGREE OF FREEDOM. SEVERAL CONCEPTS HAVE BEEN PROPOSED. THESE WILL BE DESIGNED, FABRICATED AND TESTED. LOW… more
Company: Prt Corp. Agency/Program/Year/Phase: DOD / SBIR / 1987 / 2
Abstract: THIS PROPOSAL DETAILS A DEVELOPMENT PROJECT WHICH WILL DEMONSTRATE FEASIBILITY OF A POWER-AUGMENTED EXOSKELETON. AN EXOSKELETON IS A JOINTED, EXTERNAL FRAMEWORK WORN BY A USER. FORCE SENSORS DETECT USER MOVEMENTS AND, THROUGH MODERN FEEDBACK CONTROL TECHNIQUES, POWER THE EXOSKELETON LIMBS. A USER'S… more
Company: R*scan Corp Agency/Program/Year/Phase: DOC / SBIR / 1987 / 1
Abstract: THE TECHNOLOGY OF REAL-TIME LIGHTNING GROUND STROKE MONITORING HAS ADVANCED SIGNIFICANTLY DURING THIS DECADE. THERE IS A CLEAR NEED FOR AN INTEGRATED NATIONAL LIGHTNING NETWORK. IN ORDER TO ACCOMPLISH THIS HOWEVER, TECHNIQUES MUST BE DEVELOPED TO COLLECT LIGHTNING DATA FROM GEOGRAPHICALLY SEPARATE… more
Company: Robert C. Fitch Consulting Agency/Program/Year/Phase: NSF / SBIR / 1987 / 2
Abstract: THE ARCHITECTURAL FEASIBILITY OF A GENERIC COMPUTER VISION SYSTEM COMPOSED OF HETEROGENEOUS PROCESSORS IS EXAMINED. THE STUDY FOCUSSES ON ISSUES SUCH AS THE NATURE OF THE HETEROGENEOUS PROCESSORS FUNCTIONAL CAPABILITIES, NETWORK REALIZATION TRADEOFFS, AND COMMON MODULE INTERFACES. THE GENERIC… more
Company: Apa Optics, Inc. Agency/Program/Year/Phase: DOD / SBIR / 1986 / 1
Abstract: THE NEED FOR SENSITIVE, SELECTIVE,STABLE, AND LOW COST GAS SENSORS WHICH CAN BE USED FOR IN SITE MONITORING OF AN ENVIRONMENT HAS NEVER BEEN ADEQUATELY FULFILLED. TO MEET THE TECHNICAL CHALLENGE INVOLVED IN THE DEVELOPMENT OF GAS SENSORS, APA OPTICS WILL UTILIZE INTEGRATED OPTICS TECHNOLOGY TO… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 2
Abstract: THE RAPID INCREASE IN THE NUMBER OF CHLAMYDIAL INFECTIONS AND THE SEVERE COMPLICATIONS ASSOCIATED WITH THIS DISEASE IN HUMANS HAS MADE IT IMPERATIVE TO DETECT THESE AGENTS IN BODY FLUIDS. THE UNIQUE LIFE CYCLE AND CHARACTERISTICS OF THE CHLAMYDIAL AGENTS IN GENERAL PRESENT A SIGNIFICANT HEALTH… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: DOD / SBIR / 1986 / 2
Abstract: A PROJECT IS PROPOSED TO DEVELOP TECHNIQUES FOR STABILIZATION OF PROTEINS BY COVALENT CROSSLINKING. WE PLAN TO USE MONOCLONAL ANTIBODY SPECIFIC FOR T-2 TOXIN AS THE PRIMARY PROTEIN TO USE FOR DEVELOPING STABILIZATION TECHNOLOGY. USING LIGAND STABILIZATION TO DECREASE INACTIVATION DURING THE… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: DOD / SBIR / 1986 / 2
Abstract: MUCH ATTENTION HAS BEEN FOCUSED UPON THE POSSIBLE USE OF TOXIC BIOLOGICAL AGENTS IN BOTH SOUTHEAST ASIA AND AFGANISTAN. SUCH INCIDENTS INDICATE A NEED FOR IMPROVING THE UNITED STATES CAPABILITY TO ACCURATELY DETECT THESE TOXINS AT LEVELS WELL BELOW THOSE LETHAL TO HUMANS.ONE OF THE MOST COMMON… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 2
Abstract: A PROJECT IS PROPOSED TO DEVELOP AN ULTRASENSITIVE ENZYME IMMUNOASSAY FOR SPECIFIC VIRUSES THAT IS EXPECTED TO BE MORE SENSITIVE THAN ANY CURRENTLY EXISTING TECHNOLOGY FOR THAT PURPOSE. THIS PROPOSED ASSAY INVOLVES VIRUS-TRIGGERED RELEASE OF MICROENCAPSULATED ENZYME. THE ASSAY IS NONCOMPETITIVE (I.E… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 2
Abstract: THE CONVENIENCE AND OPTICAL ADVANTAGES OF CONTACT LENSES ARE PRODUCING A GROWING MARKET FOR BOTH THE EXTENDED-WEAR AND DAILY-WEAR PRODUCTS. A NEED REMAINS FOR IMPROVEMENTS IN THE BIOCOMPATIBILITY OF BOTH CONTACT (ESPECIALLY LONG-WEAR) AND INTRAOCULAR LENSES. IN MANY USERS, THE LONG-WEAR CONTACT… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: THE DEVELOPMENT OF IMMUNOASSAYS FOR SCREENING AND MONITORINGCANCER PATIENTS AND THE PREPARATION OF TARGETED IMMUNOCHEMO-THERAPEUTIC AGENTS HAS BECOME AN INTENSE AREA OF RESEARCH. RAPID ADVANCES IN MONOCLONAL ANTIBODY TECHNOLOGY HAVE MADE POSSIBLE THE DEVELOPMENT OF THESE IMMUNOASSAYS. IT IS ACCEPTED… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: THE PURPOSE OF THIS RESEARCH IS TO DEVELOP AN ASSAY FOR BORDETELLA PERTUSSIS FROM NASOPHARYNGEAL OR THROAT SWABS TO SCREEN YOUNG CHILDREN WITH SEVERE RESPIRATORY INFECTIONS ANDOLDER CHILDREN AND ADULTS WHO HAVE HAD CONTACT WITH THE DISEASE. ALTHOUGH VACCINES HAVE REDUCED THE NUMBER OF REPORTED CASES… more
Company: SURMODICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: TRADITIONAL METHODS OF DIAGNOSIS OF VIRAL INFECTIONS HAVE BEEN PREDOMINANTLY BASED UPON ISOLATION OF VIRUSES FROM INFECTED TISSUES OR EXCRETIONS, PROPAGATION OF THE VIRUSES IN CELL CULTURES, THEN IDENTIFICATION OF THE VIRUS BY DETECTION OF SERUM ANTIBODIES AGAINST THE VIRUS. THESE METHODS OF VIRAL… more
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