Abstract:QM Power will design, build and test a high performance 3kW alternator using Parallel Path Magnetic Technology (PPMT) with no at risk rare earth magnet materials that is smaller, lighter and more efficient than the existing alternator that uses rare earth magnets. The Parallel Path Magnetic… more
Abstract:The main objective of this work is to develop and commercialize light-weight transparent composites with high tensile strength, toughness and impact resistance. Novel techniques will be developed for the design and manufacturing of these lightweight composite materials with improved blast resistance… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project applies a novel design to pneumatic solenoid valves that allows 20-25% of compressed air to be recycled. Given compressed air is one of the most expensive forms of stored energy, this energy-efficient design provides manufacturers with… more
Abstract:DESCRIPTION (provided by applicant): Physicians, no matter how well prepared, generate an average of two clinical questions per every three patient encounters. In 2009, the 1.3 billion visits to physicians' offices, hospital outpatient departments, and hospital emergency departments produced… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project seeks to improve academic advisement for seven million community college students. Advisement is a major weakness in student progress toward degree completion. The research determines whether an Internet-based advisement instrument that… more
Abstract:DESCRIPTION (provided by applicant): Pancreatic cancer (PC) is the fourth leading cause of death from cancer in the US. Treatment options for this disease are extremely limited and prognosis is poor. At present, less than 6% of PC patients are alive afterfive years with an average survival time… more
Abstract:The innovation of network forecasting is a new approach to securing industrial control networks that is based upon 1) discovering, monitoring, and modeling all devices on a network, 2) using these models to predict future device behavior, 3) evaluating past predictions with current observations of… more
Abstract:This Small Business Innovation Research Phase I project focuses on providing the proof of concept that a gamma-valerolactone (GVL) based reaction system can deliver yield and cost advantages to convert real biomass feedstocks to useful biorenewable chemicals. Glucan Biorenewables envisions… more
Abstract:Abstract Rapid microbiological methods offer great potential for increasing the reliability of pathogen detection in foods while reducing labor costs and product hold times, however, small analysis volumes limit the usefulness of these methods. Pre-enrichment is often used to overcome this… more
Abstract:The Phase II technical objective of this project is to implement the technology conceived in Phase I into hardware prototypes that can be tested in an actual HWIL test lab environment. The developments and experience acquired in Phase I will be used to design and assemble a fully functional central… more
Abstract:DESCRIPTION (provided by applicant): Vasculox, Inc. is developing a humanized anti-CD47 mAb for reducing ischemia-reperfusion injury (IRI) in organ transplantation. In spite of improvements in surgical technique, organ preservation and immunosuppression, IRI remains a serious limitation and is… more
Abstract:DESCRIPTION (provided by applicant): Acute myocardial infarction is the leading cause of death in most industrialized nations. The estimated annual incidence in the US is 865,000 events, with ST-segment elevation myocardial infarction (STEMI, severe AMI)comprising an estimated 500,000 events per… more
Abstract:DESCRIPTION (provided by applicant): The saphenous vein is the most commonly used graft for coronary artery bypass and peripheral bypass surgery, but has poor patency. 15-20% grafts fail in the first month and approximately 25% in the first year. Early vein graft occlusion is typically due to… more
Abstract:This Small Business Innovation Research Phase I project will demonstrate a highly efficient supersonic ejector vapor compression technology that converts low-to-medium grade thermal energy (200-400F) into useful refrigeration (20F-50F) at high condenser temperatures (100-120F). The proposed… more
Abstract:ABSTRACT: Miniature flat plate oscillating heat pipe (FP-OHP) heat spreaders using ThermAvant's patent-pending ThermalCircuit architecture and low CTE materials will be demonstrated in order to transfer 100-300W/cm2 from chip-sized heaters (1cm2 to 3cm2) to a heat sink area that rejects heat… more
Abstract:The objective of Phase I is the preliminary design, prototype and testing of a 3D spectral imaging system for the characterization and evaluation of viability of engineered tissue for treating war injuries. The purpose is in ensuring tissue viability, maturity, vascularity to know if a construct is… more
Abstract:ABSTRACT: High Energy X-ray computed tomography (CT) is used to inspect and evaluate the integrity of solid rocket motors (SRM"s). The driving purpose of this proposal is to improve the detection of defects in special cases where the defects are obscured due to limitations of the CT images. … more
Abstract:DESCRIPTION (provided by applicant): This research will have a significant and potentially broad impact on reducing blindness and vision loss of Americans. Many predominant eye conditions, associated with blindness and vision loss, disturb and compromise the photoreceptors. This research will enable… more
Abstract:ABSTRACT: The proposal outlines work and time tables associated with finalizing the development of wear model concepts developed in Phase I work to predict the wear of two materials sliding with respect to each other while being subjected to high velocities and/or high pressures. In parallel with… more
Abstract:DESCRIPTION (provided by applicant): Currently, more than 60 % of end-stage renal diseases patients who require chronic hemodialysis are accessed through a native arteriovenous fistula (AVF) or synthetic graft (AVG). Unfortunately, primary failure rates were as high as 60 % at 6 months after AVF… more
Abstract:DESCRIPTION (provided by applicant): Recently, Drs. Randall Bateman and David Holtzman at the Washington University School of Medicine developed a novel stable isotope labeling kinetics (SILK) methodology for measuring the metabolism of amyloid beta (AB) in the human central nervous system (CNS).… more
Abstract:ABSTRACT: MO-SCI Corporation and Missouri University of Science and Technology have developed and evaluated fusion welding technology applicable to ultra-high temperature ceramic (UHTC) composite joining during a Phase I ceramic joining program. This Phase II program will improve arc and reactive… more
Abstract:DESCRIPTION (provided by applicant): Improved long-term biocompatibility of coronary stents by plasma coating process Abstract Drug-eluting stents (DES) have been widely used to treat patients of cardiac disease due to their better ability to control restenosis than bare metal stents (BMS). However,… more
Abstract:ABSTRACT: The objective of the Phase II effort is to extend the mathematical model investigated in the Phase I to include wind speed as well as temperature modeling, continue its development for a University of Notre Dame Wind Tunnel Facility, and demonstrate utility by adopting the model to a… more
Abstract:The one CFD modeling area that has remained the most challenging, yet most critical to the success of integrated propulsion system simulations, is turbulence modeling. There is a need to develop mid-level CFD models for the interaction of turbulence and chemical reactions that give superior results… more
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