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Displaying 701 – 725 of 753 Awards
Company: Medical Microsystems Inc. Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: THE LONG-TERM OBJECTIVE IS TO COMPLETE DEVELOPMENT OF A MICROPROCESSOR-CONTROLLED MEDICATION DISPENSER THAT EFFECTIVELY ADDRESSES THE PROBLEM OF PATIENT COMPLIANCE. THIS TECHNOLOGY OFFERS THREE IMPORTANT FUNCTIONS FOR ADDRESSING NONCOMPLIANCE: (1) IT LIMITS PATIENT ACCESS TO MEDICATION ACCORDING TO… more
Company: RELIABLE BIOPHARMACEUTICAL CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1989 / 2
Abstract: SEVERAL EXPERIMENTAL ANTI-VIRAL AIDS DRUGS (AZT, DDC, DDA) ARE BASED ON CHEMICALLY MODIFIED DEOXYNUCLEOSIDES. THESE DEOXYNUCLEOSIDE DERIVATIVES ARE MADE FROM RIBONUCLEOSIDES DUE TO THE UNAVAILABILITY OF THE DEOXYNUCLEOSIDES AT A REASONABLE COST. CONSIDERING THE NEED FOR ANTI-VIRAL DRUGS AND THE… more
Company: Teknar Inc Of St Louis Agency/Program/Year/Phase: HHS / SBIR / 1989 / 1
Abstract: THIS RESEARCH WILL EVALUATE THE FEASIBILITY OF A THREE-DIMENSIONAL ULTRASOUND IMAGING SYSTEM FOR THE MALE PROSTATE. THE SYSTEM WILL BE CAPABLE OF EXTRACTING THREE-DIMENSIONAL IMAGES OF THE PROSTATE FROM SETS OF TWO-DIMENSIONAL ULTRASOUND IMAGES OBTAINED VIA A SPECIAL-PURPOSE TRANSRECTAL ULTRASOUND… more
Company: Trifid Corp Agency/Program/Year/Phase: DOD / SBIR / 1989 / 1
Abstract: METHODS ARE DEVELOPED TO APPLY SPACE BASED RIGOROUS TOPOGRAPHIC MAPPING TECHNIQUES IN EXPLOITATION OF COMMERCIALLY AVAILABLE MULTISPECTRAL IMAGERY (SPOT) IN CONJUNCTION WITH TOPOGRAPHIC DATA, DMA TERRAIN DATA (DTED), AND GEOLOGICAL MAPS, TO DO AUTOMATED GEOLOGIC MAP UPDATES, IDENTIFICATION OF… more
Company: Trifid Corp Agency/Program/Year/Phase: DOD / SBIR / 1989 / 1
Abstract: N/A
Company: Alternative Agricultural Agency/Program/Year/Phase: USDA / SBIR / 1988 / 1
Abstract: THE SMALL FAMILY FARM IN WEST CENTRAL MISSOURI ECONOMICALLY DEPRESSED. NUMEROUS STUDIES HAVE BEEN MADE ON THE DECLINE OFFAMILY FARM, THE AGING POPULATION, AND MIGRATION FROM THE FAMILY FARM. WHEN A FARM FAMILY LEAVES THE FARM, MANY PEO- PLE FROM THE SMALL TOWN ARE WITHOUT A SOCIAL FUNCTION SO THEY… more
Company: Gold Biotechnology Inc Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: N/A
Company: Incubator Technologies Inc Agency/Program/Year/Phase: NASA / SBIR / 1988 / 1
Abstract: A MICROMECHANICAL ANALYTICAL MODEL WILL BE DEVELOPED FOR PREDICTING THE FAILURE MODES IN A FIBER REINFORCED UNIDIRECTIONAL CERAMIC MATRIX COMPOSITE. THE PROPOSED MODELWILL BE BASED ON MODIFIED SHEAR-LAG THEORY THAT WOULD ACCOUNT FOR THE RELATIVELY LARGE MATRIX STIFFNESS, UP TO FIFTY PERCENT OF THE… more
Company: MO-SCI Corporation Agency/Program/Year/Phase: DOD / SBIR / 1988 / 1
Abstract: N/A
Company: INNOVATIVE SCIENCE & TECHNOLOGY Agency/Program/Year/Phase: DOE / SBIR / 1988 / 1
Abstract: CALCULATIONS AND MEASUREMENTS ARE PRESENTED TO DEMONSTRATE THAT LEAKY, CLOSED-END RESONATORS AND PARTIALLY CLOSED, OPEN-END RESONATORS CAN BE USED TO MEASURE THE PROXIMITY OF THE RESONATORS TO A SURFACE. CONVERSELY, FOR A FIXED SENSORRESONATOR POSITION, THE RESONATOR CHARACTERISTICS CAN BE USED TO… more
Company: INNOVATIVE SCIENCE & TECHNOLOGY Agency/Program/Year/Phase: DOD / SBIR / 1988 / 1
Abstract: QUITE RECENTLY, IT HAS BEEN SHOWN THAT THE IMPACT-ECHO (IE) METHOD CAN YIELD A GREAT DEAL OF INFORMATION ABOUT THE INTERNAL STRUCTURE OF CONCRETE, INCLUDING THE PRESENCE OF CRACKING AND DISBONDED REINFORCING MATERIAL. CAREFUL EXAMINATION OF THE IE METHOD, HOWEVER, SHOWS THAT UNDER MANY CIRCUMSTANCES… more
Company: Invitron Corp Agency/Program/Year/Phase: HHS / SBIR / 1988 / 2
Abstract: THE GOAL OF THIS PROJECT IS TO DEVELOP A MONOCLONAL ANTIBODY-BASED IMAGING REAGENT CAPABLE VISUALIZING HUMAN PARATHYROIDGLANDS. THE STUDY WILL BE DIRECTED AT ISOLATION AND CHARACTERIZATION OF HUMAN PARATHYROID-SPECIFIC MOUSE MONOCLONAL ANTIBODIES AND PRELIMINARY ANALYSIS OF THEIR TARGET ANTIGENS. AS… more
Company: Invitron Corp Agency/Program/Year/Phase: HHS / SBIR / 1988 / 2
Abstract: HIGH BLOOD LEVELS OF LDL HAVE BEEN ESTABLISHED AS CAUSATIVE FOR ATHEROSCLEROSIS AND CORONARY HEART DISEASE. FOR SELECTED PATIENTS, EXTRACORPOREAL LDL REMOVAL IS THE MOST EFFECTIVE THERAPY. THE GOAL OF THIS PROJECT IS TO DEVELOP AMONOCLONAL ANTIBODY-BASED IMMUNOADSORPTION DEVICE CAPABLE OF REMOVING… more
Company: Invitron Corp Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: STUDIES OF THE REGULATION OF CELL GROWTH AND OF ONCOGENIC TRANSFORMATION HAVE REVEALED KEY ROLES FOR VIRAL TRANSFORMING GENES AS WELL AS FOR EXTERNAL GROWTH AND DIFFERENTIATION FACTORS. CERTAIN VIRAL GENES HAVE BEEN USED IN THE TRANSFORMATION OF PRIMARY CELLS TO IMMORTALITY IN CULTURE, AND… more
Company: RELIABLE BIOPHARMACEUTICAL CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1988 / 1
Abstract: N/A
Company: Brewer Science Incorporated Agency/Program/Year/Phase: DOD / SBIR / 1987 / 2
Abstract: THIS PROJECT IS A STUDY OF THE EFFECTS OF POLYMERIC PHYSICAL PROPERTIES ON NEAT RESIN MECHANICAL PROPERTIES. THE POLYMER CHOSEN FOR THIS STUDY IS A POLYIMIDE SULFONE FORMED FROM BENZOPHENONE TETRACARBOXYLIC HIANHYDRIDE (BTDA) AND 3,3'-DIAMINODIPHENYLSULFONE (DDS). DURING PHASE I, SAMPLES OF… more
Company: Gold Biotechnology Inc Agency/Program/Year/Phase: HHS / SBIR / 1987 / 1
Abstract: GOLD BIOTECHNOLOGY, INC. IS STUDYING A NEW METHOD FOR GENERATING FULL-LENGTH CDNA. THIS METHOD SHOULD BE SIMPLE AND EFFICIENT AND THUS ALLOW CLONING OF BOTH RARE AND ABUNDANT MRNA. THIS METHOD IMPROVES UPON OTHER PROCEDURES IN THE FOLLOWING WAYS: (1) NO S1 NUCLEASE IS REQUIRED FOR CLONING CDNA INTO… more
Company: Imbic Corpon Agency/Program/Year/Phase: HHS / SBIR / 1987 / 1
Abstract: SEVERAL INVESTIGATORS HAVE IMPLICATED MODIFIED RIBONUCLEOSIDES, PRESUMABLY MODIFICATION PRODUCTS FROM TRANSFER RIBONUCLEIC ACIDS (TRNAS), AS POTENTIAL BIOLOGICAL MARKERS FOR CANCER. ELEVATED LEVELS OF THESE MOLECULES HAVE BEEN QUANTITATED IN THE SERUM OR URINE OF CANCER PATIENTS BY HIGH-PERFORMANCE… more
Company: Inc.ubator Technologies Inc. Agency/Program/Year/Phase: EPA / SBIR / 1987 / 2
Abstract: THE SPECIFIC OBJECTIVE OF THIS STUDY IS TO EVALUATE THE TECHNICAL FEASIBILITY OF EMPLOYING A FIXED FILM ANAEROBIC DIGESTER SYSTEM TO ACHIEVE AN ADEQUATE DEGREE OF BIOLOGICAL SLUDGE DIGESTION WITH A RETENTION TIME WHICH IS ONE ORDER OFMAGNITUDE SHORTER THAN THAT OF THE CONVENTIONAL SUSPENDED- GROWTH… more
Company: Incubator Technologies Inc Agency/Program/Year/Phase: DOD / SBIR / 1987 / 1
Abstract: CURRENT FUZES FOR CARGO DISPENSING PROJECTILES CAN ALSO BE FITTED WITH A HIGH EXPLOSIVE (HE) BOOSTER PELLET AND USED TO INITIATE HE BURSTER TYPE PROJECTILES. ITI PROPOSES TO DEVELOP A SHAPE CHARGE FUZE THAT WILL DETONATE BOTH PROJECTILES. THE PHASE I EFFORT WILL INCLUDE ANALYSIS OF THE EXISTING… more
Company: Invitron Corp Agency/Program/Year/Phase: HHS / SBIR / 1987 / 1
Abstract: PROTEASE NEXIN (PN), CDNA CLONES WERE ISOLATED FROM A HUMAN FIBROBLAST LIBRARY USING OLIGOMER PROBES DERIVED FROM THE N-TERMINAL AMINO ACID SEQUENCE OF THE PROTEIN. SEVERAL FULL-LENGTH CLONES WERE CHARACTERIZED AND FOUND TO BE APPROXIMATELY 2,100 BP LONG. THE PN CLONES CONTAINED A 1,260 BP… more
Company: Invitron Corp Agency/Program/Year/Phase: HHS / SBIR / 1987 / 1
Abstract: N/A
Company: Knowledge Software Agency/Program/Year/Phase: ED / SBIR / 1987 / 1
Abstract: KNOWLEDGE SOFTWARE PROPOSES TO DETERMINE THE TECHNICAL FEASIBILITY OF USING A MICROCOMPUTER BASED EXPERT SYSTEM TO ASSIST EDUCATORS IN THE DEVELOPMENT OF INSTRUCTIONAL OBJECTIVES. THIS EFFORT SUPPORTS THE DEPARTMENT OF EDUCATION'S GOAL OF DEVELOPING METHODS TO SIMPLIFY AND IMPROVE COURSEWARE… more
Company: Ribi Immunochem Research, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1987 / 1
Abstract: THIS PROJECT IS DIRECTED TOWARD DEVELOPMENT AND TESTING OF A LIPOSOMAL ADJUVANT SYSTEM THAT WILL ENGENDER A STRONG AND SUSTAINED IMMUNE RESPONSE TO ANTIGENS OF LOW IMMUNOGENICITY. THIS ADJUVANT SYSTEM WILL CONSIST OF LIPOSOMES THAT CONTAIN ONE OR MORE NONTOXIC IMMUNOPOTENTIATORS OF MICROBIAL OR… more
Displaying 701 – 725 of 753 Awards
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