Abstract:The future use of coal, which is projected to remain a mainstay of energy consumption well into the 21st century, will require efficient, low emission ultra-supercritical coal-fired boilers. The high operating temperature, along with the oxidizing, corroding, and slag-deposition-induced… more
Abstract:DESCRIPTION (provided by applicant): Hepatitis B virus (HBV) is a hepatotropic DNA virus that replicates by reverse transcription. It chronically infects over 350 million people worldwide and causes 600,000 deaths annually. Current therapies for HBV infect
ion use interferon 1 or one of five… more
Abstract:By drastically reducing the physical footprint of a mass spectrometer to the size of a beverage can, Ceramitron could set a new performance/price standard in the miniaturized MS market. To do this, we propose eliminating the turbomolecular and roughing pumps in favor two chemical sorption pumps (a… more
Abstract:The USAF recognizes that benefits to cold working fastener holes include significantly increased life of a structure subjected to fatigue loading. However, full realization of this potential from a maintenance and engineering standpoint is hindered by the fact that there is currently no adequate… more
Abstract:DESCRIPTION (provided by applicant): Human apyrase represents a highly promising therapy for inhibition of cancer metastasis. The enzyme strongly inhibits platelet activation and aggregation without increasing bleeding risk. Using a protein informatics app
roach, we have successfully engineered an… more
Abstract:DESCRIPTION (provided by applicant): The main objective of this SBIR Phase I research is to develop and test a software prototype. The prototype will lead to a software product. It will be a clinical tool that helps clinicians to assess the condition of pa
tients who are at risk of or who have… more
Abstract:DESCRIPTION (provided by applicant): Indocyanine Green (ICG) and Sodium Fluorescein (SF) are fluorescent dyes used clinically in eye fundus imaging, primarily for detecting vascular abnormalities in the retina and choroid, which is the layer behind the ret
ina. It is used with the Heidelberg Retinal… more
Abstract:DESCRIPTION (provided by applicant): Diabetes mellitus afflicts 20.8 million people, or 7% of the population, in the United States. Fifteen percent, or 2.4 million people, will develop diabetic foot ulcers in their life time. Diabetic foot ulceration and i
nfections are a major cause of… more
Abstract:We are utilizing the output from eye trackers to develop procedures to identify momentary lapses in alertness. The intent to deceive should be associated with the converse, momentary increases in alertness. We review literature dealing with the issue of deception as reflected in: pupil diameter,… more
Abstract:This Small Business Technology Transfer Phase I research project will demonstrate a globally asynchronous, locally synchronous (GALS) methodology for the design of large-scale, deep-submicron, System-on-Chip (SoC) integrated circuits fabricated in Field-Programmable Gate Arrays (FPGAs). The… more
Abstract:In this Phase I SBIR program, Brewer Science, Inc. (BSI), a leader in innovative microelectronic materials, and our pioneering additive manufacturing partner will develop and demonstrate a cost-effective materials production process for fabricating high-performance thin-film transistors (TFTs) using… more
Abstract:DESCRIPTION (provided by applicant): Current emphasis on metabolic approaches and models for diagnosing heart disease have renewed development of 123I SPECT imaging agents applied in stand-alone protocols and as a complimentary role to existing stress/rest
perfusion protocols. However, a majority… more
Abstract:Non Technical Summary: The goal of this research is to generate transgenic crops with broad-spectrum, season-long resistance to root knot nematode (RKN, Meloidogyne sp.). Plant parasitic nematodes, of which RKN is the most significant, annually cause damage of $8 billion in the U.S. and $78 billion… more
Abstract:Non Technical Summary: Current estimates indicate that one-third of worldwide agricultural output is lost to pests and diseases such as pathogenic fungi. Despite advancements in chemical control, the rapid onset of resistance to pesticides often limits their utility. In addition, the vast majority… more
Abstract:DESCRIPTION (provided by applicant): Parasitic infect over 140 million people, with up to one billion at risk in 80 countries. Lymphatic filariasis creates an enormous health and economic burden within affected areas and is the second leading cause of long
-term disability. In 2000, international… more
Abstract:DESCRIPTION (provided by applicant): Invasive fungal infections are an increasingly common and serious cause of illness and death in the U.S. and worldwide. Infection by Candida albicans has increased tenfold to become more frequent than diseases caused by
E. coli and Pseudomonas, and it has become… more
Abstract:The goal of this research is to generate crops, such as tomato, corn and carrot, with broad spectrum, season long resistance to root knot nematode. Plant parasitic nematodes, of which root knot is the most significant, annually cause damage in excess of $8 billion in the U.S. and $80 billion… more
Abstract:The development of very small, versatile, rugged, low power, low noise, one-or-three-axis short-period seismometers is needed to monitor nuclear detonations. Specifications include total sensor size less than 1 cubic inch, low power consumption, low sensor self-noise below the USGS Low Earth Noise… more
Abstract:The principal objective of the proposed Phase I SBIR project is the development of a reliable predictive capability for the evaluation of flaw tolerance in metallic and composite airframe components, given part specifications, material properties, initial flaws, such as voids, inclusions,… more
Abstract:This Small Business Technology Transfer Phase I project focuses on lameness which is one of the most common health problems for horses. Treatment is most effective in the earliest stages of lameness, however the subjective diagnostic methods currently used by large animal are imprecise and… more
Abstract:This Small Business Innovation Research (SBIR) Phase I research project aims to improve the frequency of homologous recombination by increasing the number of targeting vector molecules that reach the nucleus. The technology is based on constructing targeting vectors that have proteins involved in… more
Abstract:IconoPsych Care, LLC is working toward commercialization of web-based mental health services which integrate the practice of video telepsychiatry with electronic medical record keeping. This research and development effort is in response to three problems: 1) the shortage of mental health providers… more
Abstract:DESCRIPTION (provided by applicant): One of the most expensive aspects of a cryopreservation program is related to ongoing, long-term storage and shipping of samples at very low temperatures (typically between - 196oC, the temperature of liquid nitrogen (L
N2), and approximately -120oC, in the high-… more
Abstract:MO-SCI Corporation and the Missouri University of Science & Technology (MST-formerly University of Missouri-Rolla) propose to develop low cost, IR retro-reflective (800 nm - 2800 nm), visible absorbing glass microspheres for ubiquitous spectroscopic tagging through our innovative material design,… more
Abstract:Mo-Sci Corporation and the Missouri University of Science&Technology (MS&T) propose to develop novel high-strength and optically transparent glass ribbon reinforced polymer matrix composites as light-weight structural components, by layering and processing a polymer matrix reinforced with… more
There are several categories such as “By Agency”, “By Year”, “By State” etc.
Select a checkbox within a category to refine your search results.
Each of your selections is listed in the “Narrow Search Filters” bar. You can uncheck these selections to remove them.
Search for Either Criteria
When you select multiple values within a category, the results will include values that match either of the selections.
For example, selecting “2005” and “2007” in the “By Year” category will display results that include either 2005 OR 2007 in the results.
Narrowing the Search Results
You can refine your search results across categories. To narrow down your results, select multiple values across different categories. The results will only include values that match the selections across the categories.
For example, selecting “2005” in the “By Year” category and “NASA” in the “By Agency” category will only display the results that contain both “2005” AND “NASA” in the results.