Abstract:DESCRIPTION (provided by applicant): Envenomations by the brown recluse spider, Loxosceles reclusa, are a significant source of morbidity in endemic regions of the United States, and misdiagnoses are common. A survey of physicians in the endemic area has
shown the economic viability of an accurate… more
Abstract:Years of industrial investment have yielded nickel-based, austenitic, and new ferritic alloys, which have been designed to meet the creep resistance demands, of ultrasupercritical coal-fired boilers. These developments have contributed to record high commodity prices for nickel and chrome. Now, the… more
Abstract:DESCRIPTION (provided by applicant): Hepatitis C virus (HCV) infection is a major cause of liver disease throughout the world. Existing therapies are suboptimal and the search for alternative therapies is imperative. Recent years have seen a tremendous inc
rease in efforts to identify more effective… more
Abstract:This proposal offers the demonstration of an approach to integrate the latest corrosion sensor technology with corrosion structural effects modeling to enable the transition from periodic corrosion inspections to an efficient, focused prognostics and health monitoring (PHM) system. The fundamental… more
Abstract:DESCRIPTION (provided by applicant): Human apyrase represents a highly promising therapy for acute ischemic stroke which is a leading cause of death and disability with almost no effective therapy for most patients. This enzyme strongly inhibits platelet a
ctivation and aggregation with modest… more
Abstract:DESCRIPTION (provided by applicant): Human apyrase represents a highly promising therapy to reduce ischemia/reperfusion injury which occurs in10-20% of lung transplant recipients as the consequence of unavoidable processes of procurement, preservation and
restoring blood flow. This clinical… more
Abstract:X-ray computed tomography (CT) is used to evaluate the integrity of solid rocket motors (SRM's) used in the missile defense fleet. There is a need for better visualization of bondlines of materials, and detection of flaws, especially in the SRM's dome region. This problem is due to partial volume… more
Abstract:DESCRIPTION (provided by applicant): Pulmonary fibrosis, a group of incurable lung diseases with high mortality rates, is characterized by inflammatory cell infiltration, fibroblast proliferation, and excessive deposition of extracellular matrix proteins i
n lung parenchyma. Globally, five million… more
Abstract:This Small Business Technology Transfer (STTR) Phase I project will explore the feasibility of applying Radio Frequency Identification (RFID) technologies for the inventory management of time and temperature sensitive materials, which are PreMixed and Frozen (PMF) sealants that are extensively used… more
Abstract:DESCRIPTION (provided by applicant): Databases of biological sequences have proven valuable for understanding the organization of human and other genomes, for unraveling the etiology of genetic disorders, and for studying medically important pathogens. Unf
ortunately, these databases are growing at… more
Abstract:This Small Business Technology Transfer (STTR) Phase I research project aims to develop an innovative high speed IR-transparent flexible thin-film transistor (TFT) technology for application to conformal IR invisible electronics by using unique electronic-grade carbon nanotube (CNT) solutions that… more
Abstract:Bugeye Technologies, Inc. will provide research and development to design cost-effective, simulation displays, both fixed and deployable, that have increased resolution, with realistic brightness and contrast, with limited stereographic capability.
Abstract:DESCRIPTION (provided by applicant): Preterm labor, and subsequent delivery and care of premature infants, remains a major cause of infant mortality and morbidity. It is also a significant economic burden on society costing several billions of dollars a ye
ar, for the care of high-risk pregnant… more
Abstract:The technology resulting from this effort will provide a theoretical wear model which, although focused on predicting slipper surface wear associated with Air Force high-speed sleds, can be utilized with appropriate input modifications to predict wear in a range of mechanical devices where… more
Abstract:Cognitive Concepts (CC) and High Performance Technologies, Inc. (HPTi) will support the Air Force in defining objective measures of software trustworthiness, not just for embedded systems, but for a broad range of applications. The innovation is to establish measures of the inherent risks in… more
Abstract:Establishing the reliability of embedded software-based systems is increasingly important as the DoD's dependency on software grows and the size and complexity of software systems increase. Currently, no theory is in general practice that adequately explains the behavior of software systems… more
Abstract:This Small Business Innovation Reserach (SBIR) Phase I research will generate transgenic crops with resistance to plant parasitic nematodes with a focus on the lesion nematode (Pratylenchus). Plant parasitic nematodes annually cause damage of $8 billion in the U.S. and are among the most difficult… more
Abstract:DESCRIPTION (provided by applicant): Parasitic filarial nematodes causing lymphatic filariasis and river blindness (onchocerciasis), infect over 140 million people with up to one billion at risk in at least 80 countries and territories. Lymphatic filariasi
s (caused by Wuchereria and Brugia species)… more
Abstract:A computational system is required that accelerates the process of dispositioning damage to aircraft in the fleet and serves as a repository for completed repair projects that can be documented, referenced and shared. This system, which we refer to as the Rapid Repair Analysis Tool (RaRAT), will… more
Abstract:Due to large increase in the price of oil, propane, natural gas and electricity, the nations farmers are paying high costs for heating buildings. The problem can be mitigated by using biomass materials that exist, and are currently underutilized, on farms. This research seeks to develop a new… more
Abstract:This project evaluates the feasibility of developing an integrated production and
marketing system for heritage organic pork. Hogs supplied into this system will be
sourced from small organic farms that utilize heritage breeding stock, including
Berkshire and Tamworth genetics, and will be marketed… more
Abstract:IconoPsych Care LLC, is a Missouri-based company that seeks to improve the efficiency
and quality of mental health services in underserved rural communities. IconoPsychs
strategy is to fill an important niche that exists due to the current high-cost method of
mental health services in rural… more
Abstract:A glass sphere, with a refractive index of 2.0 at the surface (a miniature sphere retroreflector, with diameter in the range of 1 to 5 mm) has a number of unique properties that make it attractive for many remote sensing applications, including radiation detection in support of the DOE¿s… more
Abstract:For many applications there exists a need for mechanically strong composite materials of high optical quality and transparency equivalent to window glass. One method of increasing the mechanical strength of polymers is to reinforce them with high-strength cylindrical glass fibers. In most cases,… more
Abstract:Mo-Sci Corporation and the University of Missouri-Rolla (UMR) propose to develop novel high-strength and optically transparent glass fiber reinforced polymer matrix composites as light-weight structural components, by layering and processing a polymer matrix reinforced with glass ribbons… more
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