Abstract:DESCRIPTION (provided by applicant): This Small Business Innovation Research Phase I project will develop a commercially-viable device that uses micro-scale acoustic streaming (low frequency sound energy) to deliver mixing to the interior of three-dimensional (3D) scaffolds used for tissue… more
Abstract:DESCRIPTION: Antibiotic resistance among common bacterial pathogens is a serious public health problem as it compromises our ability to treat infectious disease. The resistance problem is compounded by the relative lack of discovery of new antibiotics, especially those with novel mechanisms of… more
Abstract:S2 Corporation and subcontractor Montana State University offer their wideband photonic technologies for signal generation and sensing and a workplan to address the needed novel characterization techniques for passive components operating over very wide bandwidth, at frequencies up to 110 GHz. In… more
Abstract:ABSTRACT: S2 Corporation and subcontractor Research Associates of Syracuse aim to develop a broadband hardware-based ultra high-speed signal processor for real time digital, broadband RF spectrum over 2-18 GHz with digital signal stream captures and analysis for a countermeasure applications, and… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will adapt a photonics based signal processor to propel applications in extreme bandwidth spread-spectrum wireless communications. The signal processor prototype known as the spatial spectral holographic (S2H) extreme bandwidth analyzer… more
Abstract:NSF SBIR Phase I Proposal 1249014 - Request for Abstract This Small Business Innovation Research Program (SBIR) Phase I project advances arbitrary waveform generation (AWG) capabilities for high bandwidth operation essential in technologies such as telecommunications, test and measurement, remote… more
Abstract:Quantifying oceanic CO2 uptake and ocean acidification and understanding their impact on global climate and ocean ecology are key goals of NOAA’s climate change research programs. NOAA’s request for Development of a long-term Lagrangian pH and pCO2 drifter (SBIR Subtopic 8.3.1C) aims to address… more
Abstract:This Small Business Innovation Research Phase II project will develop targeted nanoparticle delivery systems capable of delivering conventional cytotoxics preferentially to tumor cells. While therapeutic nanoparticles have been introduced into clinical practice (Abraxane(TM) and Doxil(TM)) and… more
Abstract:DESCRIPTION (provided by applicant): Procedures on pre-implantation embryos are a cornerstone of much biomedical research; however in all cases, the procedures are very difficult and delicate, requiring exceptionally skilled technical experts and expensive equipment. The difficulties associated… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project proposes to develop fungal bioinsecticides for control of bark beetles in forestry. Bark beetles are difficult to control. With a life cycle mostly under tree bark, exposure to insecticides is limited to the short period when adults… more
Abstract:This Small Business Innovation Research Phase I project describes a simple, novel and economical process for converting lignocellulosic feedstocks, such as wheat straw, to lipids for conversion to biodiesel and fatty acids for specialty markets (e.g. wax esters, stearic/oleic acids) using a minimal… more
Abstract:ABSTRACT: We propose to develop a lightweight, compact Cetane sensor interfaced to a fiberoptic probe immersed in the RPA fuel tank to continuously measure, update and report Cetane number to the engine electronics for control of engine settings for RPA internal combustion engines (ICE) operating… more
Abstract:DESCRIPTION: We propose to develop a new type of monitor to directly and simultaneously identify multiple biomarker metabolites in persons suspected of having been exposed to alcohol. The technology we plan to utilize is surface-enhanced Raman scattering(SERS), based on a well-known inelastic laser… more
Abstract:This SBIR Phase I effort proposes to establish the feasibility of leveraging advances in compact laser technology with integration of space qualified techniques into AdvR's Planar Lightwave Circuit (PLC) and iodine reference cell technology for the design of a space qualifiable, frequency… more
Abstract:Montana Emergent Technologies, Inc., (MET) in conjunction with the Center for Biofilm Engineering at Montana State University, proposes to investigate the feasibility of using biomineralization-based technology to seal unwanted leakage pathways relative to carbon dioxide stored in deep geologic… more
Abstract:DESCRIPTION (provided by applicant): Alzheimer's disease (AD) is a progressive and ultimately fatal neurodegenerative disease that affects more than five million people in the USA. Currently there is no cure for AD. Available medicines are aimed only at temporarily reducing symptoms and slowing… more
Abstract:This Small Business Innovation Research Phase I project will address the three major factors currently limiting the global production of bamboo fibers for composites. First, all natural fibers absorb water from the air and direct contact from the environment. Second, the strength of natural fiber… more
Abstract:23. Non-Technical Summary Phenolic and aromatic pollutants are commonly released into soils, water and the atmosphere from industrial, agricultural and human processes. Such pollutants include chlorophenols, creosote, and endocrine & #8208;disrupting chemicals (EDCs) such as estrogen and… more
Abstract:The objectives of this proposal are to further preclinical development of unique two-photon-activated photodynamic therapy (TPPDT) triads that incorporate a nontoxic porphyrin photosensitizer, a tumor targeting group, and an imaging functionality, providing for noninvasive image-guided treatment of… more
Abstract:This Navy Phase II SBIR effort will develop a packaged, high-speed optical amplitude modulator for use with a high-power, pulsed, blue laser that is being developed for lidar-based detection, ranging, and tracking of underwater objects in an ocean environment. While it is well known that laser… more
Abstract:ABSTRACT: Accurate, in-situ meteorological data are an essential part of any flight-test program or airborne weapon test. Present methods to gather such data are subject to drawbacks including spatial inaccuracy, asset availability, and simple inefficiency. An in-situ radiosonde system capable… more
Abstract:DESCRIPTION (provided by applicant): This Phase I SBIR project seeks to develop specialized protein-polymer nanoparticles that are engineered to a therapeutic drug to counter the ill effects following exposure to organophosphate (OP) insecticides. The concept for these nanoparticles is based on… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will establish proof of concept for enhancing fungal bioinsecticide to control bark beetles, important forestry pests. Although research shows potential of fungal insect pathogens as bark beetle bioinsecticides, no commercial products… more
Abstract:Resodyn Corporation is proposing a material and application system that will create a low friction coating on concrete median barriers. The advanced material developed for the low friction coating is an affordable, tough, weather resistant, and environmentally friendly copolymer. The proposed… more
Abstract:ABSTRACT: The current polyurethane based coatings on the landing skis/skids of US Air Force aircraft require frequent maintenance due to exposure to extreme conditions. A long-lasting, low-friction, hydrophobic, impact and abrasion resistant coating on the landing ski/skids is highly desired to… more
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