Abstract:With the advent of improved body armor and vehicles and the enemy"s use of the improved explosion device (IED) in the most recent conflicts, blast injuries and related burns to the face have become more and more common among our Wounded Warriors. Pathological scarring, which often results in… more
Abstract:No currently available burn product has shown efficacy in substantially decreasing wound healing time and preventing scar formation. The goals of this Phase II proposal are to expand on the results obtained in the Phase I study that showed that (1) halofuginone inhibited collagen-mediated… more
Abstract:The overall goal of this Phase I SBIR application is to develop a non-cell-based means of inhibiting coagulation and platelet activation on engineered vascular grafts, so that small-diameter arterial grafts may be available off the shelf. This arterial graft will consist of human engineered tissue… more
Abstract:The proposal seeks to significantly automate the process of producing parts requiring multi-axis milling of sculpted surfaces as required by the Navy for hydro-shapes such as propellers. Harnessing recent university research involving the application of graphical processing units as inexpensive… more
Abstract:There is growing interest in computerized systems to increase accessibility
of assessments for students with disabilities. Technology offers an ideal platform for implementing Universal Design (UD) principles for assessment to better accommodate student diversity and support broad student… more
Abstract:Employment is essential for helping individuals with intellectual disabilities achieve independence, financial security, and self-sufficiency to be active members in the community as well as foster a higher quality of life more generally. However, only 25% of individuals with intellectual… more
Abstract:DESCRIPTION (provided by applicant): A central aspect of any research project is data collection, and within the clinical, behavioral, and social fields of study, data collection is traditionally carried out in-person, by telephone, or through the mail andoften involves research participants… more
Abstract:DESCRIPTION (provided by applicant): Dropping out of school costs the nation up to 350 billion annually, in lost wages, unemployment, incarceration costs, welfare dependence, and health care costs. Moreover, poorer individual health and well-being resultfrom dropping out. Despite recent reductions… more
Abstract:As emphasized by the NIH Roadmap and NCATS's Strategic Priorities, NIH's broad mission to improve health outcomes for all persons depends on the ability to train and retain future generations of clinical scientists who can quickly and effectively translateresearch findings into clinical… more
Abstract:DESCRIPTION (provided by applicant): This Phase I SBIR application is submitted in response to the call by DHHS for new tests for qualitative measurement of HCV RNA for diagnosis of chronic HCV infection in patients. The need is for HCV RNA assays that areas reliable but less expensive and… more
Abstract:DESCRIPTION (provided by applicant): Lead poisoning harms millions of people, yet is an entirely preventable health problem. The objective of this SBIR on Point-of-Care Tests for Blood Lead Levels in Children is to develop a significantly better blood lead test to identify and protect those at… more
Abstract:Abstract We propose to initiate preclinical development of a gene therapeutic targeted to Alzheimer's Disease. The World Health Organization's and Alzheimer's Disease International's report on Dementia (2012) recognizes that the global burden of AlzheimerDisease is forecast to… more
Abstract:DESCRIPTION (provided by applicant): Ophthalmic vascular diseases impact millions of Americans. Age-related macular degeneration and diabetic retinopathy are the two major diseases with a well- known vascular factor. The role of the vascular system in glaucoma and retinopathy of prematurity is more… more
Abstract:DESCRIPTION (provided by applicant): Each year, over 20 million ophthalmic surgeries are performed worldwide. Indications for ophthalmic surgery include potentially blinding diseases, such as cataracts, diabetic retinopathy, macular disease, and retinal detachment. Surgeons performing these delicate… more
Abstract:? DESCRIPTION (provided by applicant): The Clinical Challenge: Alcohol project seeks to improve outcomes of patients with at risk alcohol use or an alcohol use disorder by improving the alcohol assessment and intervention skills of medical students. Toaccomplish this goal we will build upon our… more
Abstract:DESCRIPTION (provided by applicant): Over 24 million Americans suffer from asthma, which has become a chronic inflammatory disease of the airways characterized by reversible airflow obstruction and bronchospasm together with symptoms of wheezing, coughing,shortness of breath, and chest tightness.… more
Abstract:On today"s battlefields, vehicles are at risk of encountering improvised explosive devices (IEDs). Fortunately, not all of these result in complete vehicle loss. Following events at both ends of the severity spectrum, Battle Damage Assessment and Repair (BDAR) and event reconstruction efforts… more
Abstract:ABSTRACT: Corvid Technologies, in partnership with Clemson University"s combustion modeling group, is pleased to offer a physical sub-model evaluation and development plan for turbulent combustion applications relevant to the Air Force. We will leverage the computational resources and… more
Abstract:Corvid Technologies is proposing an inconspicuous armor solution for SOCOM NSCVs that will offer less costly installation than the current steel shell. This effort will benefit from Corvid"s experience in rapid development of specialized low cost armor systems. Armor coverage of the vehicle… more
Abstract:During our Phase I SBIR program for topic MDA-073-019, Hypervelocity Intercept Modeling with First-Principle, Physics Based Tools, we showed the utility of First-Principle Codes (FPC), specifically Velodyne, in modeling missile intercept phenomenology. In addition, we identified a path toward the… more
Abstract:The objective of this proposed Phase II effort is to continue leveraging first principles physics based codes for modeling the high and low-order explosive response and characterizing the resulting debris for HE submunitions warheads in missile intercepts. Corvid"s approach will include… more
Abstract:Corvid Technologies is pleased to offer this STTR Phase II proposal in collaboration with The Johns Hopkins University Applied Physics Laboratory (JHU/APL), Spectral Sciences Inc. and Torch Technologies. Capabilities from each collaborator are being combined toward the ability to perform accurate,… more
Abstract:This Small Business Innovation Research Phase I project addresses the need to improve the state of the art in efficient air disinfection by introducing a novel disinfection reactor developed around an optimized proprietary optical design in conjunction with an engineered suite of wavelengths… more
Abstract:DESCRIPTION (provided by applicant): In 2008, there were 47,560 new cases of head and neck cancers (HNC) in the United States. Early detection of new and locally recurrent cancers is clinically important to reduce not only cancer related mortality, but also treatment associated morbidity as it… more
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