Abstract:Corvid Technologies is pleased to offer this STTR Phase I proposal in collaboration with The Johns Hopkins University Applied Physics Laboratory and Spectral Sciences, Incorporated. The emphasis of the proposed effort is to develop a new methodology for predicting late-time EO/IR signatures from… more
Abstract:Corvid Technologies in collaboration with Dynetics, Inc ("Dynetics") is pleased to present the following proposal to the Missile Defense Agency (MDA) SBIR solicitation MDA12-028 entitled Improved Target Discrimination of Multiple Targets Using Bulk Filtering for Debris. This proposal will… more
Abstract:As MDA continues implementation of the Phased Adaptive Approach (PAA), robust operation of BMDS sensors within post-intercept debris environments will become more critical to successful operation of the larger BMDS. Due to a paucity of test data, development and performance testing of BMDS sensors… more
Abstract:The objective of the proposed Phase II program is to leverage existing first-principle physics-based codes and improve our ability to predict lethality outcomes for hypervelocity missile intercepts using our Velodyne code. In particular, we will address deficiencies in our high explosive (HE)… more
Abstract:Corvid Technologies is pleased to offer comprehensive computational analysis, experimental testing, and design of an advanced warhead. The objective is to design a warhead capable of overpressure defeat of point detonating fuses in rocket, artillery, and mortar (RAM) targets. A successful Phase I… more
Abstract:Corvid Technologies is excited to offer a unique solution for protecting tactical vehicles during high-speed external transport. The innovative design employs a fabric net structure rigged to the vehicle which significantly reduces the impeding air velocity on critical components. This approach… more
Abstract:DESCRIPTION (provided by applicant): Standard microfracture is a first-line, widely used and cost-effective surgical technique for repairing damaged articular cartilage, but, it is limited by decreased long-term efficacy and limited applicability in largerlesions. This leads to a burgeoning economic… more
Abstract:DESCRIPTION (provided by applicant): Controlling mechanical signal transduction to treat osteoarthritis Abstract The TRPV4 calcium (Ca++) permeable ion channel has been shown to be expressed and functional in chondrocytes, the cells responsible for the maintenance of cartilage in weight-bearing… more
Abstract:DESCRIPTION (provided by applicant): The overall goal of this study is to develop a tissue-engineered total joint replacement from an engineered biomaterial scaffold combined with adult bone marrow-derived mesenchymal stem cells (MSCs) for regeneration ofthe entire femoral surface of the hip joint.… more
Abstract:DESCRIPTION (provided by applicant): The goal of this Phase I effort is determine the feasibility of developing a unique antimicrobial catheter to reduce the instances of the most prevalent healthcare associated infection, Catheter-Associated Urinary TractInfection (CAUTI). This research and… more
Abstract:DESCRIPTION (provided by applicant): Medical drugs and devices are regulated by the U.S. Food and Drug Administration (FDA) based on data from multicenter clinical trials. In 2010, U.S. spending on clinical trials was approximately 25 billion. Over the past decade the efficiency of clinical trials… more
Abstract:DyMA-FM (Dynamic Multivariate Assessment for Fault Management) is a software architecture for real-time fault management. Designed to run in a distributed environment, DyMA-FM enables model-based reasoning and predictive modeling for FM applications. With the appropriate hardware, DyMA-FM can… more
Abstract:DESCRIPTION (provided by applicant): Acute kidney injury (AKI) is common, expensive, and highly morbid. There are currently no therapies for AKI, and prevention and treatment represents a 6.3 billion market opportunity annually in the U.S. Moreover, patients are developing AKI more frequently and… more
Abstract:DESCRIPTION (provided by applicant): Myelosuppression continues to represent the major dose-limiting toxicity of cancer chemotherapy, resulting in considerable morbidity and mortality along with frequent reductions in chemotherapy dose intensity, which maycompromise disease control and survival.… more
Abstract:DESCRIPTION (provided by applicant): Patients with infective endocarditis (IE) have a poor prognosis with one third of the patients succumbing to the infection within the first year. Treatments for endocarditis involve antibiotic therapy and/or surgery that cost upwards of 100,000 per patient;… more
Abstract:DESCRIPTION (provided by applicant): Training mentored youth and their caregivers to work together successfully with their mentor and mentoring program is critically important for achieving a safe, high-quality, sustained mentoring relationship, and for obtaining positive youth outcomes. Training… more
Abstract:PROJECT SUMARY/ABSTRACT This proposed project is in response to the need for more extensive toxicological evaluation of environmental chemicals and for predictive models to assess associated risks of chemical exposure to humans. There is also need for innovative methods for evaluating the effects of… more
Abstract:Although several critical energy saving technologies under development today require Gallium Nitride (GaN) based semiconductor devices, a source of high quality and inexpensive GaN wafers does not yet exist. This lack of GaN wafers adds complexity to GaN device production and makes development of… more
Abstract:Gallium Nitrides (GaN) device market size is second only to silicon and is projected to be $50-100 billion in size as markets mature for GaN power devices, solid state lighting, and hundreds of other new applications. Even with this remarkable forecast, GaN epitaxy is still produced primarily on… more
Abstract:Gallium Nitride (GaN) crystals have recently garnered attention as a candidate for use as a Quasi-Phase Matching (QPM) material for frequency conversion applications such as second harmonic generation (SHG) and optical parametric oscillation (OPO), due to its wide bandgap (3.4eV), high thermal… more
Abstract:In Phase I, a novel porous electrode was designed to demonstrate a rapid, simple assay for the detection of domoic acid in marine samples. During Phase II, methods to manufacture porous electrodes will be improved to enable high volume production of low-cost biosensors that can be connected to a… more
Abstract:Through this effort, NanoTechLabs Inc. will improve the efficiency and lower the mass of the cryogenic heat exchanger used in American Superconductor's High Temperature Superconducting Degaussing system. NanoTechLabs will achieve these goals by producing a Carbon Nanotube metal matrix composite… more
Abstract:ABSTRACT: Through the Phase II program, NTL will finalize the materials development and demonstrate the ability of a TIM material based on carbon nanotube vertical arrays to meet general requirements for space applications. In addition we will define and initiate tests required for a specific Air… more
Abstract:DESCRIPTION (provided by applicant): Mucus transport is the fundamental defense of the airways against inhaled particulates/infectious agents. Abnormalities in the mucus transport system characterize a complex of muco-obstructive airway diseases, such as cystic fibrosis (CF) and chronic bronchitis… more
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