Abstract:DESCRIPTION (provided by applicant): Current assays employed to assess the potential of drugs and environmental agents for their potential to cause birth defects involve the use of animal models. Not only are these models costly and time consuming, but they also have poor concordance to human data.… more
Abstract:We plan to implement a planar Molecularly Controlled Semiconductor Resistor (MOCSER) gas sensor on both InAs and InN platforms for the ppt-ppm detection of NOx and H2O. Kyma Technologies and Duke University will leverage Duke"s leading MOCSER based NOx sensor technology which uses surface… more
Abstract:Aluminum Gallium Nitride (AlGaN) has broad dual use applications for power transistors, high frequency transistors, high power Schottky barrier diodes, and solar-blind detectors, as well as ultra-violet laser diodes and ultra-violet light emitting diodes. This unique material system spans the… more
Abstract:The overall objective of this program is to improve the producibility of HVPE GaN through the use of in-situ monitoring during the growth process. Various in-situ monitoring devices will be used: a UV absorption technique to monitor the GaCl concentration above the growing GaN wafer; a commercial… more
Abstract:In this proposal, we build on demonstrated expertise in Bulk GaN growth (Kyma Technologies), High Indium Mole Fraction InGaN and quaternary AlInGaN growth (NCSU- Salah Bedair), device fabrication and characterization (NCSU- John Muth), Optical Photopumping (ARMDEC- Henry Everitt) and expertise in… more
Abstract:In this proposal, we build on demonstrated expertise in Bulk GaN growth (Kyma Technologies), Design and simulation of Power Devices and systems (NextWatt LLC), Epitaxial Growth of High Performance HEMT heterostructures (Virginia Commonwealth University), and Fabrication of Advanced Semiconductor… more
Abstract:Gallium nitride (GaN) substrates are a critical component in the roadmap of power efficient and high frequency electronic devices in the coming years. One major hurdle of this technology is the limited availability of large diameter, high quality substrates for large scale device fabrication. Under… more
Abstract:This Small Business Innovation Research Phase II project will develop long fiber thermoplastic (LFT) compositions based on recycled carbon fiber. In Phase I, we demonstrated the ability to make high quality LFT formulations based on (1) waste carbon fiber and (2) composites scrap and end-of-life… more
Abstract:This project will develop a low-cost tooling system for prepreg composite molding capable of processing epoxy-and BMI- matrix composites at temperatures of 400F (205C). Such a tooling system would be applicable to advanced airframe components including both military applications and commercial… more
Abstract:There is a need for a simple, portable, quantitative method to monitor the presence of Harmful Algal Blooms. Electrochemical detection offers some advantages for analysis, but traditional sensors are not practical for routine field use. Adapting colorimetric immunoassays on porous, flow-through… more
Abstract:ABSTRACT: In this Phase I Air Force SBIR program, NanoTechLabs (NTL)will develop a space-qualifiable, high-conductance, thermal interface material (TIM) for use in space-based flanged heat-pipe-to-heat-pipe joints or for mounting relatively small area units with stiff baseplates and high power… more
Abstract:In this Phase I effort, NanoTechLabs will develop a family of related products/techniques for improving the performance of carbon fiber structural composites by introducing small amounts of carbon nanotubes into structurally critical areas. These new carbon nanotube structural products will be… more
Abstract:The future capabilities of sensors and instrumentation deployed in space will continue to increase, resulting in increasing amounts of collected data. To reach these higher speed data rates, increases to the overall system gain of the communication link will be required. A deterministic method to… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project aims to develop the process and engineering controls necessary to scale up the manufacturing of a nitric-oxide-releasing active pharmaceutical ingredient (API). One of the applications is a wound-healing product for diabetic foot ulcers… more
Abstract:Under battlefield conditions, warfighters face a wide range of cutaneous injuries, many of which are susceptible to life- and limb-threatening infections caused by multi-drug resistant bacteria. Nitric oxide is a powerful, broad spectrum antimicrobial agent that is naturally produced by the immune… more
Abstract:DESCRIPTION: Globally, an estimated 322,000 individuals die from fire-related burn injuries each year. In the United States, 450,000 experience burns requiring hospitalization and 3,500 of these lead to fatal outcomes. A burn of 30% of total body area cancost as much as 200,000 in initial… more
Abstract:DESCRIPTION (provided by applicant): This application proposes to build on the successful Phase I Picture Me Alcohol Free (PMAF) feasibility pilot study. PMAF is a community-based program designed to train groups of youth to a) represent contributing factors and consequences (e.g., social… more
Abstract:ABSTRACT: The Air Force has invested considerable resources into collecting and synthesizing radar data for training and testing ATC/R systems. Significant cost savings may be realized if these existing datasets may be leveraged for training new sensors and modalities. Signal Innovations Group… more
Abstract:DESCRIPTION (provided by applicant): Invasive aspergillosis (IA) caused by the fungus Aspergillus fumigatus is the most frequent fungal cause of death in immunocompromised patients. The number of patients at risk for developing IA is steadily increasing due to advances in medicine. Early and… more
Abstract:DESCRIPTION (provided by applicant): This Phase I Small Business Innovation Research (SBIR) proposal seeks to develop an innovative, inexpensive, and reliable system, called the Tummy-Time Motivator (TTM), to motivate children to improve postural control.Postural control is the foundation for the… more
Abstract:DESCRIPTION (provided by applicant): The objective of this Phase I SBIR application is the proof-of-principle for an innovative and reliable subdermal electroencephalogram (EEG) monitor. The EEG is the most widely-used monitor of brain function. Over a fifth of the population suffers from brain… more
Abstract:DESCRIPTION (provided by applicant): The SCID is the 'gold standard' for all research-based mental health diagnoses in the United States and for CNS clinical trials worldwide. But, it has been expensive and cumbersome to administer. In Phase I and II of this project we successfully… more
Abstract:DESCRIPTION (provided by applicant): The human inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis, affect over one million Americans and significant unmet medical needs still exist. Activation of NF??B transcription factors are central events in the initiation and… more
Abstract:Purpose: Students with high functioning autism spectrum disorders (HF-ASD) face unique challenges with social skills and social relationships, often experiencing heightened levels of social isolation and exclusion from social opportunities. Without intervention, these social difficulties can… more
Abstract:DESCRIPTION: In the medical device industry, silicone oil is a ubiquitous lubricant used in the manufacture, assembly of medical components, and also as the terminal lubricant for proper device operation. In prefilled syringes, problems arise when micro-droplets of silicone oil migrate into the… more
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