Abstract:A group of chemotactic cytokines belonging to the "chemokine" family have recently beenidentified and molecularly cloned. These include the archetypal alpha and beta subfamily membersinterleukin-8, a neutrophil selective chemoattractant and the monocyte chemoattractant protein-1(MCP-1). Chemotactic… more
Abstract:This proposed effort utilizes an existing DoD technology, known as a traveling wave tube (TWT), as a broadband, high-power plasma source. The TWT will permit optimization of processing parameters over a frequency range larger and wider than has previously been examined and will allow optimum,… more
Abstract:The proposed project is to develop a microwave processing system for variable frequency processing of thermosetting polymer matrix composites (PMCs). Combining an existing production technology with an innovative application of DoD Traveling Wave Tube (TWT) technology will enable an increase in the… more
Abstract:Our company will develop a method of automatically programming neural-networks to extractneeded information from databases of biological and chemical information. We will pursue the creationof a framework for training a neural network to predict the toxic and carcinogenic properties ofchemicals… more
Abstract:RCS Technologies, Inc. (hereafter referred to as RCS) has developed a method for producing fine grained transparent spinel ceramics (hereafter referred to as "RCS spinel") that offer significant cost savings over traditional hard optical materials. RCS spinel holds the promise of producing infrared… more
Abstract:We will construct and evaluate a PC-based test of alcohol-induced impairment that will bedistributed to research laboratories throughout the United States. We will develop a normative databasefor computerized impairment testing. The Phase l project produces a low cost, software test derivedfrom a… more
Abstract:A HIGHLY EFFICIENT TWO STAGE POROUS MEDIA COMBUSTOR IS PLANNED WHICH WILL ALLOW CLEAN COMBUSTION OF LOW BTU COAL GAS. EXPERIMENTS IN PHASE I WILL DEMONSTRATE THE TECHNICAL AND ECONOMIC FEASIBILITY OF THE TECHNOLOGY. SEVERAL POROUS MEDIA WHICH ARE SUITABLE FOR THIS APPLICATION WILL BE INVESTIGATED… more
Abstract:Discovery of new drugs depends largely upon random screening directed towards specificenzyme targets. Protein kinase C (PKC), a family of serine/threonine-specific protein kinases, is criticalin the control of multiple cellular responses, including gene expression, proliferation, differentiation… more
Abstract:Lithium thermal batteries offer superior properties, such as long shelf life, high power capacity, high reliability, and ability to operate in a wide temperature range, as well as in dynamic environments. These properties make the lithium thermal battery a viable candidate for the expendable 35 kW… more
Abstract:Nickel hydrogen batteries are well established for use in satellite applications, due to their excellent cycle life, no maintenance and high reliability. These excellent characteristics are mitigated by the use of high pressure vessels for hydrogen storage. Nickel/metal hydride batteries have same… more
Abstract:This proposed Phase I program focuses on the development of a novel solid electrolyte that is low cost and has the potential of yielding high conductivity for lithium ion.s These novel materials have stable crystal structures and are quite robust up to temperatures of 560 degrees celcius. Objectives… more
Abstract:NASA requires a safe, long-cycle-life lithium battery that is rechargeable, efficient and reliable for powering space electronics. A solid polymer electrolyte for lithium batteries will allow placement of the electrodes in close proximity, bipolar cell construction, retardation of undesirable… more
Abstract:2D real-time phased array ultrasound has become a dominant medical imaging modality due to low costs, high efficacy and the absence of ionizing radiation. The total worldwide market for diagnostic ultrasound is $2 billion annually. Real-time phased array volumetric scanning systems (often called "4D… more
Abstract:This Phase I program will investigate the potential for paraffinic phase change materials (PCMs) to provide a light, passive, and non-burdensome body undergarment theraal manageaent system for the USMC. Based on Biaterials and technologies developed under eight previous SBIE prograBis for NASA, USAF… more
Abstract:FIELD PROGRAMMABLE GATE ARRAYS (FPGAS) AND FIELD PROGRAMMABLE INTERCONNECT DEVICES (FPIDS) HAVE THE ABILITY TO INTEGRATE THOUSANDS OF LOGIC GATES ON A SMALL BOARD IN WHICH THE INTERCONNECTIONS CAN BE COMPLETELY REARRANGED WITHIN MILLISECONDS WITHOUT MANUAL EFFORT. USING FPGAS AND FPIDS, IT IS NOW… more
Abstract:This research develops, tests, and disseminates a curriculum-based program which is effectivein preventing the onset of substance use and abuse among adolescents. The program is delivered in theinitial year to middle or junior high school by trained specialists. Programmatic focus addressesmediating… more
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