Abstract:THE REQUIREMENTS OF COMPLEX SAMPLE MONITORING PRESENT A GROWING NEED FOR A NEW GENERATION OF HIGHLY SPECIFIC ENZYME ELETRODES WITH MULTI-ANALYTE, MULTI-SIGNAL CAPABILITY. THIS PROJECT'S OBJECTIVE IS TO ESTABLISH THE FEASIBILITY OF NOVEL ELECTROCHEMICAL SENSORS BASED ON THE COMBINATION OF… more
Abstract:At this time it is very difficult to distinguish viral infections from bacterial infections. Published results suggest that some subtypes of interferon-alpha (INF-a) are present in viral infections and are not detected in bacterial infections but no clinically useful assay for this potential marker… more
Abstract:The requirements of complex sample monitoring present a growing need for a new generation of highlyenzyme electrodes that operate in non-processed or raw samples and have multi-analyte capability. This to establish the feasibility of novel colloidal gold/immobilized enzyme based raw… more
Abstract:This Phase I effort will investigate the feasibility of basic concepts for a hillside straddle tractor. A true straddle tractor for tall crops on hillsides does not currently exist. This straddle tractor, the Smart Mountain Mule (SMM), will be designed as a tool for Christmas tree farms in hilly… more
Abstract:The contract will develop a Shoulder Launched unmanned Reconnaissance System (SLURS) that can be carried, launched and flown by a single soldier. The system consists of a Reconnaissance Air Vehicle (RAV), Launcher, a Ground Control Subsystem (GCS), and several Individual observer Units (IOU). A… more
Abstract:Phase I is directed at the development of a rapid and quantitative diagnostic immunoassay for acuteinjury. This immunoassay will utilize a proven dry chemistry test system incorporating a cardiac-spechemically conjugated to active-site inactivated coagulation factor Xa. The test principle… more
Abstract:The major impediment to the wide implementation of DNA diagnostic methods is their cost. Technologisimplify current DNA diagnostic methods and to make them cost competitive with antibody based assaysdesirable. Our new selective silver staining technology could dramatically enhance the… more
Abstract:Boron Neutron Capture Therapy (BNCT) is a very promising therapy for certain tumors, such as gliomamelanomas. p-Boronophenylalanine (BPA), an analog of phenylalanine, is one of the leading BNCT agentundergoing clinical trials in the U.S. for the treatment of gliomas and melanomas. It has already… more
Abstract:The rapid development of the technology for producing high quality single crystal SiC wafers and thin films presents the opportunity to fabricate solid-state devices with power-temperature capability far greater than devices currently available. While conventional silicon power devices are already… more
Abstract:Gallium Nitride has been known for many years to have excellent physical and electronic properties which are well suited to the production of electronic devices that can emit radiation in the blue-to-green region of the spectrum, detect UV radiation, and operate at significantly higher temperatures… more
Abstract:THE PURPOSE OF THE PROPOSED RESEARCH IS TO DEVELOP A DATABASE OF MATERIALS COMMONLY FOUND IN LUGGAGE. THIS WOULD INCLUDE DATA ON WHAT TYPES OF ARTICLES ARE TYPICALLY FOUND IN LUGGAGE AND DATA ON THE ELEMENTAL COMPOSITION AND PHYSICAL PROPERTIES OF THESE ARTICLES. THE DATABASE WOULD BE USED IN THE… more
Abstract:The detection of specific DNA sequences for the diagnosis of genetic diseases, cancer, and infectious disease is becoming increasingly widespread. A number of innovative techniques have been employed, including the oligonucleotide ligation assay and reverse dot-blot hybridization. The end-point, and… more
Abstract:Recombinant cytokines could be used to augment immune responses during periods of bird production such as the embryonic/early posthatch stage when birds are most susceptible to disease. However, only seven avian cytokines have been cloned and no recombinant avian cytokines are presently available… more
Abstract:A system for the accurate localization and fixation of the prostate during the planning and treatmecancer using radiation therapy is to be developed. The visualization of the prostate gland is achievtransrectal ultrasonography. During treatment planning, the precise position of the prostate gland… more
Abstract:THE RECENT ADVENT OF A DIGITAL, BROADHAND, HAND-HELD ELECTROMAGNETIC (EM) SENSOR PROVIDES AN OPPURTUNITY FOR A SIGNIFICANT ADVANCE IN RAPID AND MEANINGFUL SITE CHARACTERIZATION FOR DEPTH RANGES AND CONDITIONS WHERE GROUND PENETRATING RADAR (GPR) IS INEFFECTIVE. THIS PROPOSAL PRESENTS A FEASIBILITY… more
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