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Displaying 1901 – 1925 of 2211 Awards
Company: Program Development, Training Agency/Program/Year/Phase: HHS / SBIR / 1994 / 1
Abstract: This research develops, tests, and disseminates a curriculum-based program which is effectivein preventing the onset of substance use and abuse among adolescents. The program is delivered in theinitial year to middle or junior high school by trained specialists. Programmatic focus addressesmediating… more
Company: 4pi Analysis, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1993 / 1
Abstract: N/A
Company: ALDERON BIOSCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 1993 / 1
Abstract: N/A
Company: ALDERON BIOSCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 1993 / 2
Abstract: N/A
Company: Biotherm, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1993 / 2
Abstract: A TEST SYSTEM FOR RAPID SCREENING OF PATIENTS PRIOR TO INITIATION OF THROMBOLYTIC THERAPY WILL BE DEVELOPED. THIS SYSTEM WILL BE BASED ON A NOVEL DRY REAGENT ASSAY TECHNOLOGY WHICH RECENTLY HAS BEEN APPLIED SUCCESSFULLY TO PT AND ACTIVATED PTT TESTS. INTRODUCTION OF A RAPID CONVENIENT TEST OF… more
Company: BORON BIOLOGICALS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1993 / 2
Abstract: USE OF NUCLEOSIDE PHOSPHATES AS ANTITUMOR AND ANTIVIRAL AGENTS HAS BEEN LIMITED BY THEIR INABILITY TO PENETRATE CELL MEMBRANES AS WELL AS THEIR HIGH SUSCEPTIBILITY TO ENZYMES SUCH AS PHOSPHATASES, NUCLEOTIDASES, ETC. MODIFICATION OF THE PHOSPHATE GROUP (BY REPLACING ONE OF THE NONBRIDGING OXYGENS… more
Company: BORON BIOLOGICALS, INC. Agency/Program/Year/Phase: DOE / SBIR / 1993 / 2
Abstract: NEUTRON CAPTURE THERAPY IS A VERY PROMISING THERAPY FOR CERTAIN TUMORS, SUCH AS GLIOMAS AND MELANOMAS. SEVERAL NUCLEI HAVE HIGH CROSS SECTIONS FOR THERMAL NEUTRONS, OF WHICH BORON-10 ((10)B) AND GADOLINIUM-157 ((157)GD) HAVE BEEN SHOWN TO BE VERY PROMISING. (10)B HAS A HIGH CROSS SECTION FOR THERMAL… more
Company: BORON BIOLOGICALS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1993 / 1
Abstract: The main objective of the research is to develop a new class of topoisomerase II (Topo II) inhibitors as antineoplastic agents. In preliminary studies, heterocyclic amine-carboxyboranes have been shown to possess cytotoxic activity against a number of murine and human tumor tissue culture lines, e.… more
Company: BORON BIOLOGICALS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1993 / 1
Abstract: We will design and synthesize novel nucleic acid base derivatives containing cyanoborane group attached to a pyridine-type nitrogen atom of the purine or the pyrimidine cycle. The cyanoboronated bases may be designed to be more membrane soluble than the respective 2'- deoxyribonucleosides of known… more
Company: BORON BIOLOGICALS, INC. Agency/Program/Year/Phase: HHS / SBIR / 1993 / 1
Abstract: A major problem with the use of nucleoside phosphates as antiviral and antitumor drugs has been their inability to penetrate cell membranes. Additionally, nucleoside phosphates are susceptible to phosphatases and nucleases, which reduce their in vivo life time. Replacement of the charged phosphate… more
Company: Carolinian Systems Research Agency/Program/Year/Phase: DOD / SBIR / 1993 / 1
Abstract: A new approach to signal detection and classification is applied to the problem of ASW and torpedo defense for shallow-water environments. The approach is particularly appropriate for applications where the statistics of the signal and the noise are unknown and highly variable. The primary goal is a… more
Company: CREE RESEARCH, INC. Agency/Program/Year/Phase: DOD / SBIR / 1993 / 2
Abstract: There is an increasing need in many military systems to have solid state microwave devices with higher power capability, higher reliability, and higher operating temperatures. These devices would be important for airborne radar systems, electronic warfare and countermeasure systems, and airborne and… more
Company: CREE RESEARCH, INC. Agency/Program/Year/Phase: DOD / SBIR / 1993 / 2
Abstract: Silicon carbide possesses a unique combination of properties, not available from other more common semiconductors, which allow it to operate in certain severe environments. These properties include a wide bandgap, a high melting point, high breakdown electric field, and high thermal conductivity, as… more
Company: CREE RESEARCH, INC. Agency/Program/Year/Phase: NSF / SBIR / 1993 / 1
Abstract: BETA-SIC HAS BEEN KNOWN FOR MANY YEARS TO HAVE EXCELLENT THEORETICAL PROPERTIES FOR THE PRODUCTION OF HIGH POWER MICROWAVE DEVICES. THE COMBINATION OF ITS WIDE BANDGAP (2.2 EV @ 27 DEGREES CENTIGRADE), HIGH SATURATED ELECTRON DRIFT VELOCITY (2.5x10(7) CM/SEC), HIGH BREAKDOWN ELECTRIC FIELD (4x10(6)… more
Company: CREE RESEARCH, INC. Agency/Program/Year/Phase: NASA / SBIR / 1993 / 2
Abstract: N/A
Company: CREE RESEARCH, INC. Agency/Program/Year/Phase: DOD / SBIR / 1993 / 1
Abstract: N/A
Company: ELCATECH, INC. Agency/Program/Year/Phase: HHS / SBIR / 1993 / 1
Abstract: N/A
Company: Ftc Acquisition Corp Agency/Program/Year/Phase: DOD / SBIR / 1993 / 1
Abstract: This program will demonstrate the applicability of the freeze crystallization (FC) process dirctly to U.S. Air Force environmental managers by, in phase I, (1) finding applications that are well served by this technology, (2) demonstrating the capabilities of the FC process by processing wastes in… more
Company: Ftc Acquisition Corp Agency/Program/Year/Phase: DOD / SBIR / 1993 / 1
Abstract: When loading nitrogen tetroxide before launching the space shuttle, fugitive N2O4 is absorbed into caustic solutions in a two stage scrubber solution. The second stage of the scrubber has sodium sulfite added to the alkaline scrubbing solution to act as an oxidant scavenger, to improve scrubbing… more
Company: Higher Power Engineering Agency/Program/Year/Phase: DOD / SBIR / 1993 / 1
Abstract: N/A
Company: Instatherm Co Agency/Program/Year/Phase: DOE / SBIR / 1993 / 1
Abstract: THE PROVISION OF ACCEPTABLE LEVELS OF OCCUPANT COMFORT IN AN ELECTRIC VEHICLE (EV) ADDS CONSIDERABLY TO THE LOAD ON THE BATTERY SYSTEM. BATTERIES BARELY STORE ENOUGH ENERGY TO PROVIDE AN ADEQUATE RANGE WITHOUT ANY AUXILIARY LOAD. THE ADDITION OF MAJOR POWER-CONSUMING OPTIONS, SUCH AS AIR… more
Company: Integrated Silicon Systems Agency/Program/Year/Phase: DOD / SBIR / 1993 / 1
Abstract: N/A
Company: Novel Pharmaceuticals Agency/Program/Year/Phase: HHS / SBIR / 1993 / 1
Abstract: The intent is to create an artificial intelligence software system which accurately predicts chemical toxicity. The system will use a neural network to recognize patterns and correlation between chemical structure/substructures, physicochemical properties, and toxicologic/carcinogenic findings. An… more
Displaying 1901 – 1925 of 2211 Awards
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